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  1. Analysis of the oxidative stress-dependent transcriptome in mouse bone marrow-derived macrophages NURSA

    Keywords: myeloid lineage macrophages bone marrow-derived

    Description: Bone marrow derived macrophages from C57Bl/6 mice were treated for 4 h with or without (i) lipopolysaccharide; (ii) oxidative stress-derived extracell...

    ID: 10.1621/pbcLTrujND

  2. Analysis of the peroxisome proliferator activated receptor α (PPARα/Ppara)- and perfluorooctanoic acid (PFOA)-regulated transcriptomes in mouse liiv... NURSA

    Keywords: whole liver

    Description: Liver was isolated from male 129S4/SvJae-Pparatm1Gonz/J PPARα/Ppara knockout or wild type mice treated with 3 mg/kg/d PFOA or vehicle for 7 d or 10 d...

    ID: 10.1621/Z2mx7YCBjw

  3. Time course analysis of the 17β-estradiol (17βE2)-dependent transcriptome in rat vagina NURSA

    Keywords: whole vagina

    Description: Vaginas were removed from ovariectomized 9 week old Sprague Dawley rats treated with or without 20 µg/kg body weight 17βE2 for 6 h, 3 d or 5 d.

    ID: 10.1621/Fh5YpJbKia

  4. Analysis of the rosiglitazone (Rosi)-regulated transcriptome in Prdm16-depleted mouse differentiating preadipocytes NURSA

    Keywords: WAT preadipocytes inguinal 1° cells

    Description: Primary preadipocytes from inguinal white adipose tissue were infected with an adenoviral vector expressing a scrambled control shRNA or Prdm16 shRNA ...

    ID: 10.1621/dYqMBEjruH

  5. Time course analysis of the methylprednisolone (MePred)-regulated transcriptomine in rat skeletal muscle NURSA

    Keywords: gastrocnemius whole

    Description: Adrenalectomized male Wistar rats weighing 339 ± 28 grams were treated with or without 0.3 mg/kg/hr MePred via Alzet osmotic pump for a range of time...

    ID: 10.1621/SnRGxa6Pww

  6. Analysis of the human TFEB-regulated, peroxisome proliferator activated receptor-α (PPARα/Ppara)-dependent mouse hepatic transcriptome NURSA

    Keywords: whole liver

    Description: Liver was isolated from male C57BL/6 PPARα/Ppara knockout and wild-type mice injected with an adenoviral vector expressing human TFEB under control o...

    ID: 10.1621/z9Uf4gBgoY

  7. Comparison of selective estrogen receptor modulator-regulated transcriptomes in MCF-7 cells NURSA

    Keywords: epithelium MCF-7 cells

    Description: Human MCF-7 breast cancer cells were treated for 24 h with or without 10 nM 17β-estradiol (17βE2), 100 nM bazedoxifene acetate (Baz), 100 nM Fulvest...

    ID: 10.1621/AxDT4iAOyZ

  8. Mutational analysis of the aryl hydrocarbon receptor (Ahr)-regulated transcriptome in 2,3,7,8-tetrachlorodibenzodioxin (TCDD) and benzo[a]pyrene-treat... NURSA

    Keywords: epithelium Hepa-1c1c7 cells

    Description: Wild type mouse Hepa-1c1c7 hepatoma cells or Hepa-1c1c7 cells overexpressing an Ahr DNA-binding mutant were treated for 8 h with vehicle, 5 uM benzo[a...

    ID: 10.1621/VcaZL4Ue3h

  9. Analysis of the testosterone (Test)-regulated transcriptome in mouse gastrocnemius muscle NURSA

    Keywords: gastrocnemius whole

    Description: Gastrocnemius muscle was isolated from young adult CD-1 mice that had undergone castration or sham surgery and treated with or without a 2.5 mg Test p...

    ID: 10.1621/ZyfMZkn28g

  10. Analysis of the Hopx-dependent transcriptome in mouse embryoid bodies during cardiac differentiation NURSA

    Keywords: pluripotent embryoid bodies

    Description: Mouse embryonic stem cells derived from Hopx KO and Hopx HET blastocysts were cultured as embryoid bodies for 8 d.

    ID: 10.1621/f5aPqW9mLU

  11. Analysis of the retinoid orphan receptor-α (RORα/Rora) and retinoid orphan receptor -γ (RORγ/Rorg)-regulated murine hepatic transcriptome NURSA

    Keywords: whole liver

    Description: Liver was isolated from male C57Bl/6 liver-specific RORα/Rora-RORγ/Rorg double knockout and wild-type mice housed on a 12:12-hour light–dark cycle...

    ID: 10.1621/KhIRY2C9Iq

  12. Analysis of the peroxisome proliferator activated receptor-δ (PPARδ/Ppard)-regulated transcriptome in mouse bone marrow-derive macrophages NURSA

    Keywords: myeloid lineage macrophages bone marrow-derived

    Description: Bone marrow derived macrophages were isolated from PPARδ/Ppard KO and WT mice.

    ID: 10.1621/6gOjFZUwg6

  13. Analysis of the TP63-, STAT3-, and rosiglitazone (Rosi)-regulated transcriptomes in human bladder cancer cell lines NURSA

    Keywords: epithelium UM-UC-7 cells

    Description: Human urothelial cancer cells were: stably transduced with lentivirus expressing TP63 shRNA or negative control shRNA (U14 cells); stably transfected ...

    ID: 10.1621/llORkOYdMO

  14. Analysis of the retinoic acid receptor-related orphan receptor (RORγ/Rorc)-regulated transcriptome in mouse colonic lamina propria regulatory T lymph... NURSA

    Keywords: lymphoid lineage T lymphocytes regulatory colon lamina propria

    Description: Transcriptomes were compared between RORγ/Rorc +ve and RORγ/Rorc -ve colonic lamina propria Tregs, and between total colonic lamina propria and sple...

    ID: 10.1621/unaqBTdkb0

  15. Analysis of the chronic rosiglitazone (Rosi)-regulated transcriptome in stromal vascular adipocyte progenitors NURSA

    Keywords: WAT adipocytes unspecified 1° cells

    Description: GFP+ adipose progenitor cells were FACS-isolated from adult AdipoTrak mice (PPARgamma-tTA;tetO-H2B-GFP) fed for 2 mo with a diet containing 0.0075% Ro...

    ID: 10.1621/8Z7R4UyWys

  16. Comparative timecourse analysis of the white adipose tissue transcriptome from non-diabetic and diabetic rat models administered normal and high fat d... NURSA

    Keywords: WAT retroperitoneal

    Description: White adipose tissue was isolated from Goto-Kakizaki (GK) rats, a polygenic non-obese model of type 2 diabetes, and non-diabetic Wistar-Kyoto (WKY) co...

    ID: 10.1621/vwixe8FrnC

  17. Analysis of the dibutyryl-cAMP (dbcAMP)-regulated, Ppargc1a-dependent transcriptome in brown adipose tissue NURSA

    Keywords: BAT unspecified

    Description: Immortalized preadipocyte cell lines derived from the interscapular BAT of WT and Ppargc1a KO mice were differentiated into brown adipose tissue for 7...

    ID: 10.1621/kKZxgaOCNd

  18. Analysis of the estrogen-related receptor β (ERRβ/Esrrb)-dependent, sonic hedgehog (Shh)-regulated transcriptome in mouse 3T3-L1 adipocytes NURSA

    Keywords: WAT adipocytes 3T3-L1-derived

    Description: Mouse 3T3-L1 preadipocytes stably expressing a ERRβ/Esrrb expression vector were cultured for 48 h in the presence or absence of Shh conditioned medi...

    ID: 10.1621/Z2tGKt3DrO

  19. Acute and chronic time course analysis of the clofibrate (clofib)-regulated transcriptome in Female ovariectomized C57BL/6 mouse liver. NURSA

    Keywords: whole liver

    Description: Livers were isolated from mice treated for 2 - 24 h or 1 - 14 d with or without 300 mg/kg bw/d clofib.

    ID: 10.1621/tIZetW6Ie8

  20. Analysis of the Tgfb1/Smad3-regulated white adipose tissue (WAT) transcriptome in a mouse model of diet induced obesity NURSA

    Keywords: WAT epididymal

    Description: WAT was isolated from Smad3 KO and WT male mice fed a HFD (55% [w/w] fat content) or a control diet (5% [w/w] fat content) for 10 w. WAT was also isol...

    ID: 10.1621/yG7RrbFzac

  21. Analysis of the mesenteric white adipose transcriptome in a model of diet induced obesity NURSA

    Keywords: WAT mesenteric

    Description: Mesenteric white adipose tissue surrounding the pancreas was isolated from adult male Wistar rats fed a standard chow diet (supplying 8% of calories a...

    ID: 10.1621/tRuonbce2a

  22. Analysis of the murine RU486-dependent caudate putamen transcriptome in a model of LPS-induced inflammation NURSA

    Keywords: striatum putamen

    Description: Male C57Bl/6 mice 60 days of age received an i.p. injection of (1) 50 mg/kg bw RU486; an infusion of (2) 2.5 µg LPS; or (3) combinations of both. Bra...

    ID: 10.1621/JjzjzBw61o

  23. Time course analysis of the 17α-ethinylestradiol (17αEE2)-regulated transcriptome in mouse uterus NURSA

    Keywords: whole uterus

    Description: Uteri were removed from ovariectomized C57BL/6 mice treated with or without 0.1 mg/kg bw 17αEE2 via oral gavage for range of time periods between 2 h...

    ID: 10.1621/lyCqB9nmMg


Displaying 50 of 10,773 results for " "