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  1. Microarray analysis of gene expression changes in human A549 lung cancer cells upon siRNA knockdown of FAM60A and SDS3 OmicsDI

    ID: E-GEOD-39733

    Date Released: 08-18-2015

    Description: The Sin3 histone deacetylase (HDAC) complex is a 1.2 MDa chromatin modifying complex that can repress transcription by binding to gene promoters and d...

  2. Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of Trophoblast Stem Cells OmicsDI

    ID: E-MTAB-3565

    Date Released: 08-18-2015

    Description: Derivation and maintenance of TS cells depends on the presence of Fgf signalling. Numerous gene knock-out experiments identified the mitogen activated...

  3. Expression data from breast cancer tumor-initiating cells OmicsDI

    ID: E-GEOD-32526

    Date Released: 08-14-2015

    Description: We have generated tumorigenic (S2N) and non-tumorigenic (S2), normal-like to basal-like breast cancer cell lines from primary tumors. At high in vivo ...

  4. Expression data from knockdown of G9a in MDA-MB231 cells OmicsDI

    ID: E-GEOD-34925

    Date Released: 08-17-2015

    Description: G9a is an H3K9m2 methyltransferase, which is critical in controlling gene suppression and DNA methylation. We used microarray analysis to identify the...

  5. High-throughput sequencing of mouse liver transcriptome in Clock mutant animals OmicsDI

    ID: E-GEOD-41082

    Date Released: 08-19-2015

    Description: Circadian profile of polyA RNA by RNA-Seq, collected from ClockΔ19 mouse liver at CT22, CT28, CT34, CT40. RNA from three livers pooled per time point...

  6. RNA-Seq profiling of single bovine oocyte transcript abundance and its modulation by cytoplasmic polyadenylation OmicsDI

    ID: E-GEOD-61717

    Date Released: 08-19-2015

    Description: Polyadenylated RNA from individual germinal vesicle and metaphase II ooyctes was amplified and processed for Illumina sequencing. Increases in polyade...

  7. Molecular anatomy of palate development OmicsDI

    ID: E-GEOD-67525

    Date Released: 08-19-2015

    Description: Background: The FACEBASE consortium was established in part to create a central resource for craniofacial researchers. One purpose is to provide a mol...

  8. Transciptional response to acute thermal stress in Chinook salmon OmicsDI

    ID: E-GEOD-59756

    Date Released: 08-19-2015

    Description: Thermal stress is a serious and growing challenge facing Chinook salmon (Oncorhynchus tshawytscha) living in the southern portion of their native rang...

  9. Interactions of melanoma cells with distal keratinocytes trigger metastasis via Notch signaling inhibition of MITF OmicsDI

    ID: E-GEOD-69403

    Date Released: 08-19-2015

    Description: The most critical stage in initiation of melanoma metastasis is the radial to vertical growth transition, yet the triggers of this transition remain e...

  10. A Myc transcriptional program that is independent of EMT drives a poor prognosis tumor-propagating phenotype in HER2+ breast cancer OmicsDI

    ID: E-GEOD-43730

    Date Released: 08-19-2015

    Description: The HER2 (ERBB2) and MYC genes are commonly amplified genes in breast cancer, yet little is known about their molecular and clinical interaction. Usin...

  11. Gene expression alterations in human colon cancer xenograft treated with anti-VEGF antibody OmicsDI

    ID: E-GEOD-47087

    Date Released: 08-18-2015

    Description: Recent randomized clinical trial revealed the additional effect of bevacizumab, a humanized monoclonal antibody against vascular endothelial growth fa...

  12. Molecular changes induced in melanoma cells by stromal cells and anti-BRAF therapy. OmicsDI

    ID: E-GEOD-67637

    Date Released: 08-19-2015

    Description: Tumor-associated stromal cells can enable cancer cells to become insensitive to therapy. They can promote aggressive phenotype in cancer cells, which ...

  13. Expression profile of U373 cells over-expressing DTX1 and cells expressing a dominant negative form of MAML1 OmicsDI

    ID: E-GEOD-22772

    Date Released: 08-10-2015

    Description: Glioblastoma multiforme (GBM) is the most malignant and most common tumor of the central nervous system characterized by rapid growth and extensive ti...

  14. Networking of differentially expressed genes in human MCF7 breast cancer cells resistant to methotrexate OmicsDI

    ID: E-GEOD-16070

    Date Released: 08-06-2015

    Description: A summary of the work associated to these microarrays is the following: The need for an integrated view of all data obtained from high-throughput tec...

  15. Expression data from human skin exposed to solar-simulated radiation with or without sunscreen OmicsDI

    ID: E-GEOD-22083

    Date Released: 08-10-2015

    Description: Despite widespread use of sunscreens that minimize erythema by blocking ultraviolet B (UVB) radiation, incidence rates of melanoma continue to rise. ...

  16. A Randomized, Placebo-Controlled Study to Evaluate SRT2104, a Selective SIRT1 Activator, in Patients with Moderate to Severe Psoriasis OmicsDI

    ID: E-GEOD-50614

    Date Released: 08-07-2015

    Description: Activation of Sirtuin (silent mating type information regulation 2 homolog) 1, or SIRT1, is an unexplored therapeutic approach for treatment of inflam...

  17. Networking of differentially expressed genes in human K562 erythtoblastic leukemia cells resistant to methotrexate OmicsDI

    ID: E-GEOD-16085

    Date Released: 08-06-2015

    Description: A summary of the work associated to these microarrays is the following: The need for an integrated view of all data obtained from high-throughput tec...

  18. Transcriptional profiling of A549 lung adenocarcinoma cells in response to overexpression or supression of X-ray responsive microRNAs to identify regu... OmicsDI

    ID: E-GEOD-30131

    Date Released: 08-12-2015

    Description: 'MicroRNA (miRNA) is a type of non-coding RNA that regulates the expression of its target genes by interacting with the complementary sequence of the ...

  19. Expression data of MCF7/ADR cells treated with MC70, an ABC transporters inhibitor OmicsDI

    ID: E-GEOD-26250

    Date Released: 08-12-2015

    Description: A major limitation in the cancer treatment is the ability of cancer cells to become resistant to chemotherapeutic drugs, by multidrug establishment. H...

  20. Profiling of p53-responsive genes in human breast cancer cells harboring endogenous ts-p53 E285K OmicsDI

    ID: E-GEOD-35006

    Date Released: 08-17-2015

    Description: The ts-p53 E285K protein is a rare p53 mutant with temperature-sensitive (ts) loss of function characteristics. In cancer cells, which express ts-p53 ...

  21. Expression data from cultured human lung tissue-derived fibroblasts and human vascular adventitial fibroblasts OmicsDI

    ID: E-GEOD-26146

    Date Released: 08-12-2015

    Description: In order to find the difference between human lung tissue-derived fibroblasts and human vascular adventitial fibroblasts for enhancing tumor formation...

  22. Expression profile of MDA-MB-231 and MCF7 cells stably transfected with GFP-Numb4, GFP-Numb5, GFP-Numb6 OmicsDI

    ID: E-GEOD-29137

    Date Released: 08-12-2015

    Description: Numb has 4 known variants and we are reporting two novel Numb variants, Numb5 and Numb6 in this study. The metastaticability variations between the nu...

  23. Expression data from MCF7 cells treated with Neuregulin (NRG) at different times OmicsDI

    ID: E-GEOD-69540

    Date Released: 08-05-2015

    Description: To gain insights into the mechanism responsible for the protumorigenic actions of NRG we performed gene expression analyses of MCF7 cells treated with...

  24. Expression data from MCF-7 cells stimulated by Estrogen or IGF-I OmicsDI

    ID: E-GEOD-26834

    Date Released: 08-11-2015

    Description: Although estrogen receptor (ER) and insulin-like growth factor (IGF) signaling are important for normal mammary development and breast cancer, cross-t...

  25. Networking of differentially expressed genes in human MDA-MB-468 breast cancer cells resistant to methotrexate OmicsDI

    ID: E-GEOD-16080

    Date Released: 08-06-2015

    Description: A summary of the work associated to these microarrays is the following: The need for an integrated view of all data obtained from high-throughput tec...

  26. Candidate genes for the recurrence of glioblastoma multiforme identified by microarray OmicsDI

    ID: E-GEOD-13276

    Date Released: 08-06-2015

    Description: Background: Glioblastoma multiforme (GBM) is the most aggressive and most lethal primary malignant brain tumor, correlated with survival rates of less...

  27. Genome-Wide Expression Profiling of human tumor-infiltrating microglia/macrophages stimulated by Toll-like receptor 3 agonist poly (I:C) OmicsDI

    ID: E-GEOD-25289

    Date Released: 08-10-2015

    Description: Microglia isolated from glioma patients gain anti-tumor activities upon poly (I:C) stimulation. Expression profiles of human tumor-infiltrating microg...

  28. Microarray characterization of gene expression changes in blood during acute ethanol exposure OmicsDI

    ID: E-GEOD-20489

    Date Released: 08-07-2015

    Description: As part of the civil aviation safety program to define the adverse effects of ethanol on flying performance, we present results of our DNA microarray ...

  29. Defining the Genomic Signature of the Parous Breast OmicsDI

    ID: E-GEOD-26457

    Date Released: 08-11-2015

    Description: It is widely accepted that a woman’s lifetime risk of developing breast cancer at menopause is reduced by early full term pregnancy and multiparity....

  30. Mutant p53 Disrupts Mammary Acinar Morphogenesis via the Mevalonate Pathway OmicsDI

    ID: E-GEOD-31812

    Date Released: 08-13-2015

    Description: p53 is a frequent target for mutation in human tumors and previous studies have revealed that these missense mutant proteins can actively contribute t...

  31. SIN3A-regulated LIF-responsive genes in MCF7 cells OmicsDI

    ID: E-GEOD-35696

    Date Released: 08-17-2015

    Description: Tyrosine phosphorylation is a hallmark for activation of Signal Transducer and Activator of Transcription (STAT) proteins, but their transcriptional a...

  32. Transcription profiling by array of human MCF10A cells over-expressing HRas or MEK1 OmicsDI

    ID: E-GEOD-12764

    Date Released: 08-12-2015

    Description: MCF10A cells were then transfected with MEK1(S217S221), HRAS(G12V), and null control vectors; Cells were lysed 24 hours post-transfection with collect...

  33. Claudin 1 mediates TNF alpha-induced gene expression and cell migration in human lung carcinoma cells OmicsDI

    ID: E-GEOD-32254

    Date Released: 08-14-2015

    Description: Epithelial-mesenchymal transition (EMT) is an important mechanism in carcinogenesis. To determine the mechanisms that are involved in the regulation o...

  34. Innate lymphoid cell development requires TOX-dependent generation of a common ILC progenitor OmicsDI

    ID: E-GEOD-65850

    Date Released: 08-05-2015

    Description: Subtypes of innate lymphoid cells (ILC), defined by effector function and transcription factor expression, have recently been identified. In the adul...

  35. Expression data from breast tumors and reduction mammoplasty explants OmicsDI

    ID: E-GEOD-25407

    Date Released: 08-10-2015

    Description: Breast tumorigenesis involves modulation of gene expression. We used microarrays to detail the global program of gene expression underlying breast tum...

  36. DNA Methylation Profiling of Glioblastoma: Impact on Gene Expression and Clinical Outcome (Agilent Expression Study) OmicsDI

    ID: E-GEOD-22866

    Date Released: 08-07-2015

    Description: Genome-scale measurements of DNA methylation levels are necessary to decipher the epigenetic events involved in glioblastoma aggressive phenotype, and...

  37. Gene expression signatures of symptomatic respiratory viral infection in adults OmicsDI

    ID: E-GEOD-17156

    Date Released: 08-10-2015

    Description: Diagnosis of acute respiratory viral infection is currently based on clinical symptoms and pathogen detection. Use of host peripheral blood gene expr...

  38. gene expression profiling of three type of grade II gliomas OmicsDI

    ID: E-GEOD-21354

    Date Released: 08-07-2015

    Description: In this study we performed gene expression profiling of 14 cases of grade II gliomas. The results of these analysis were used in unsupervised analyses...

  39. S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells [HG-U133_Plus_2] OmicsDI

    ID: E-GEOD-19278

    Date Released: 08-06-2015

    Description: We and others have shown that S100P is highly upregulated during the progression of pancreatic cancer. We used microarrays to look at the target genes...

  40. Transcription profiling by array of human glioblastoma mulitforme tumors after dendritic cell vaccination OmicsDI

    ID: E-GEOD-11100

    Date Released: 08-05-2015

    Description: Human Glioblastoma Multiforme tumors taken before dendritic cell vaccination, the recurrent tumors taken after vaccination and control GBM tumors from...

  41. Expression data from human PBMC induced by mixed Congeners of PCBs at Human equivalence OmicsDI

    ID: E-GEOD-22668

    Date Released: 08-05-2015

    Description: Exposure to Polychlorobiphenyls (PCBs) is known to cause serious health effects in human but the gene expression profiles leading to development of di...

  42. Transcription profiling by array of human cancer cell lines resistant to methotrexate OmicsDI

    ID: E-GEOD-16648

    Date Released: 08-06-2015

    Description: This SuperSeries is composed of the following subset Series:; GSE11440: Role of Caveolin 1, E-Cadherin, Enolase 2 and PKCa on resistance to methotrexa...

  43. Characterization of protoporphytin IX effects on X-ray irradiation in Hela cells in vitro OmicsDI

    ID: E-GEOD-61805

    Date Released: 08-05-2015

    Description: Hela cells were used to evaluate the protoporphytin IX (PpIX) effects on X-ray irradiation. Treatment conditions were (1) control group (untreated cel...

  44. Resveratrol induces downregulation of DNA repair genes in MCF7 human breast cancer cells. OmicsDI

    ID: E-GEOD-25412

    Date Released: 08-10-2015

    Description: Breast cancer is a worlwide health problem. One of the factors involved in carcinogenesis is diet. Several studies indicate that resveratrol, a polyph...

  45. Expression data from MDA-MB-231 cells treated with vehicle or YW3-56 OmicsDI

    ID: E-GEOD-46590

    Date Released: 08-05-2015

    Description: PAD4 is overexpressed in many cancer cells. We developed PAD inhibitors that efficiently inhibit the cancer cell growth. One inhibitor YW3-56 could ef...

  46. mRNA expression data from BCR-ABL, MYC and CD22DE12 transgenic mouse models OmicsDI

    ID: E-GEOD-58872

    Date Released: 06-26-2015

    Description: Leukemic splenocytes from these commercial transgenic mice that developed fatal leukemia with massive splenomegaly were isolated at the time of the ne...

  47. caArray_hanas-00078: Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis OmicsDI

    ID: E-GEOD-70231

    Date Released: 06-26-2015

    Description: Astrocytomas are heterogeneous intracranial glial neoplasms ranging from the highly aggressive malignant glioblastoma multiforme (GBM) to the indolent...

  48. Human Calu-3 cell transcriptome response to human interferon α [miRNA] OmicsDI

    ID: E-GEOD-70220

    Date Released: 06-26-2015

    Description: The purpose is to obtain samples for mRNA and miRNA analysis with and without interferon α treatment; in parallel, to obtain cell pellets to forward ...

  49. Large scale analysis of apple mealiness within IM apple progeny OmicsDI

    ID: E-GEOD-59947

    Date Released: 06-26-2015

    Description: Based on sensorial analysis over 4 years, 6 apple genotypes with contrasted fruit texture (mealy or not) were selected among a progeny. Apple samples ...

  50. Comprehensive genomic analysis of relapse neuroblastoma [arrayCGH] OmicsDI

    ID: E-GEOD-65304

    Date Released: 06-27-2015

    Description: Relapse neuroblastoma were characterized by sequencing, gene expression, arrayCGH and genome-wide methylation. This data set contains the aCGH data. A...


Displaying 50 of 78,272 results for " "