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Displaying 20 of 78,352 results for " "
  1. Vascular niche induction of hematopoietic progenitors from pluripotent stem cells OmicsDI

    ID: E-GEOD-64644

    Date Released: 01-01-2016

    Description: Pluripotent stem cells (PSC) represent an alternative source of hematopoietic stem cells (HSCs). Clinical translation is impeded by limited engraftmen...

  2. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (II) OmicsDI

    ID: E-GEOD-70613

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  3. Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [hMSC microarray] OmicsDI

    ID: E-GEOD-73601

    Date Released: 01-02-2016

    Description: The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. Here we report that Mdm2 is required for the ...

  4. Models of Human Core Transcriptional Regulatory Circuitries OmicsDI

    ID: E-GEOD-76181

    Date Released: 12-27-2015

    Description: A small set of core transcription factors (TFs) dominates control of the gene expression program in embryonic stem cells and other well-studied cellul...

  5. G72 overexpression in U87 cells OmicsDI

    ID: E-GEOD-67704

    Date Released: 01-01-2016

    Description: G72 is a susceptible gene for schizophrenia. No matter genetic variation or serum levels, G72 has been recognized as a biomarker for schizophrenia. In...

  6. The effects of aging on circadian patterns of gene expression in the human prefrontal cortex OmicsDI

    ID: E-GEOD-71620

    Date Released: 01-02-2016

    Description: With aging, significant changes in circadian rhythms occur, including a shift in phase toward a “morning” chronotype and a loss of rhythmicity in ...

  7. ERK activation, gene dysregulations and cell transformation at submicromolar doses of Cr6+ in C3H10T1/2 and BALB/c 3T3 cells: interaction with Lipoic ... OmicsDI

    ID: E-GEOD-43156

    Date Released: 01-02-2016

    Description: The molecular mechanism of Cr6+ carcinogenicity is not well understood. Studies advocate a key involvement of the altered cytogenomics and dysregulate...

  8. The homeobox transcription factor Nkx2-1 regulates microRNAs controlling downstream gene silencing in lung epithelial cells (mRNA) OmicsDI

    ID: E-GEOD-47054

    Date Released: 12-26-2015

    Description: Cell-specific gene expression is achieved by a combination of mechanisms including transcriptional and post-transcriptional regulation. The transcript...

  9. Synergistic activity of BET protein antagonist-based combinations in Mantle Cell Lymphoma cells sensitive or resistant to ibrutinib OmicsDI

    ID: E-GEOD-70651

    Date Released: 01-02-2016

    Description: To determine the global transcriptome changes in mantle cell lymphoma cells following treatment with the BET bromodomain antagonist, JQ1 Mantle Cell L...

  10. Hormetic shifting of redox environment by the ROS-producing polyphenol resveratrol protects cells from oxidative stress OmicsDI

    ID: E-GEOD-72119

    Date Released: 01-02-2016

    Description: Resveratrol is a natural product that has gained tremendous interest due to multiple reported health-beneficial effects. However, the underlying mecha...

  11. CodeLink Mouse Whole Genome Bioarray data from hematopoietic stem cells (HSCs) of miR-125a (+/+) wild-type and miR-125a knockout mice with myeloprolif... OmicsDI

    ID: E-GEOD-69621

    Date Released: 01-01-2016

    Description: miR-125a knockout mice develop myeloproliferative disorder (MPD). To investigate the molecular mechanisms of MPD induced by the loss of miR-125a, gene...

  12. Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells OmicsDI

    ID: E-GEOD-66796

    Date Released: 12-26-2015

    Description: The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined the promoter methylome of purified and uncultured...

  13. Gene expression of 7 day combinatorial yohimbine and imipramine treated rat hippocampi OmicsDI

    ID: E-GEOD-61301

    Date Released: 01-03-2016

    Description: Rats treated on 7 consecutive days with either 2 injections of vehicle (Ctl) (DMSO for yohimbine, saline for imipramine) or Y+I (2mg/kg Yohimbine + 20...

  14. Cumulative low doses of the organic pesticide rotenone in the adult rat substantia nigra pars compacta OmicsDI

    ID: E-GEOD-22364

    Date Released: 01-02-2016

    Description: Adult male Sprague Dawley rats (5 month-old at the beginning of the study) were subcutaneously exposed to 0.5 rotenone or the corresponding so...

  15. Global Analysis of the Transcriptional Response of Chinese cabbage (Brassica rapa ssp. pekinensis) to Methyl Jasmonate Reveals JA Signaling on Enhance... OmicsDI

    ID: E-GEOD-51363

    Date Released: 01-03-2016

    Description: We conducted a RNA-Seq analysis of MeJA-treated Chinese cabbage leaf transcriptome. Total 14,619,469 sequence reads were generated to produce 27,461 d...

  16. Gene expression changes in Apc-mutant mouse intestinal organoids 7 and 20 days after the induction of the Apc deletion OmicsDI

    ID: E-GEOD-47569

    Date Released: 01-02-2016

    Description: We isolated and selected intestinal adenoma organoids from Lgr5-EGFP-IRES-CreER; Apcflox/flox mice and added tamoxifen to induce the deletion of the A...

  17. 5-Day Gavage Study of Propylene glycol phenyl ether (PPH; CASRN 770-35-4) in Male Harlan Sprague Dawley Rats OmicsDI

    ID: E-GEOD-75656

    Date Released: 01-02-2016

    Description: The goal of this study was to characterize the potential toxicity and genomic benchmark dose of propylene glycol phenyl etherl in liver and kidney of...

  18. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (I) OmicsDI

    ID: E-GEOD-70611

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  19. Genome-wide mapping of TEL-AML1 targets in acute leukemia OmicsDI

    ID: E-GEOD-67519

    Date Released: 01-03-2016

    Description: Around 20-25% of childhood acute lymphoblastic leukemias carry the TEL-AML1 (TA) fusion gene. It is a fusion of two central hematopoietic transcriptio...

  20. Transcription profiling by high throughput sequencing of Arabidopsis estradiol-inducible tor-es mutant OmicsDI

    ID: E-MTAB-4132

    Date Released: 01-04-2016

    Description: To validate that the transcriptional program rapidly activated by PP242, WYE354, KU63794 and Torin2 was specifically associated with the complete inhi...

Displaying 20 of 78,352 results for " "