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  1. Vascular niche induction of hematopoietic progenitors from pluripotent stem cells OmicsDI

    ID: E-GEOD-64644

    Date Released: 01-01-2016

    Description: Pluripotent stem cells (PSC) represent an alternative source of hematopoietic stem cells (HSCs). Clinical translation is impeded by limited engraftmen...

  2. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (II) OmicsDI

    ID: E-GEOD-70613

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  3. Mdm2 enhances stemness-promoting chromatin modifications through the Polycomb Repressor Complex 2 in a p53-Independent Manner [hMSC microarray] OmicsDI

    ID: E-GEOD-73601

    Date Released: 01-02-2016

    Description: The Mdm2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. Here we report that Mdm2 is required for the ...

  4. Models of Human Core Transcriptional Regulatory Circuitries OmicsDI

    ID: E-GEOD-76181

    Date Released: 12-27-2015

    Description: A small set of core transcription factors (TFs) dominates control of the gene expression program in embryonic stem cells and other well-studied cellul...

  5. G72 overexpression in U87 cells OmicsDI

    ID: E-GEOD-67704

    Date Released: 01-01-2016

    Description: G72 is a susceptible gene for schizophrenia. No matter genetic variation or serum levels, G72 has been recognized as a biomarker for schizophrenia. In...

  6. The effects of aging on circadian patterns of gene expression in the human prefrontal cortex OmicsDI

    ID: E-GEOD-71620

    Date Released: 01-02-2016

    Description: With aging, significant changes in circadian rhythms occur, including a shift in phase toward a “morning” chronotype and a loss of rhythmicity in ...

  7. ERK activation, gene dysregulations and cell transformation at submicromolar doses of Cr6+ in C3H10T1/2 and BALB/c 3T3 cells: interaction with Lipoic ... OmicsDI

    ID: E-GEOD-43156

    Date Released: 01-02-2016

    Description: The molecular mechanism of Cr6+ carcinogenicity is not well understood. Studies advocate a key involvement of the altered cytogenomics and dysregulate...

  8. The homeobox transcription factor Nkx2-1 regulates microRNAs controlling downstream gene silencing in lung epithelial cells (mRNA) OmicsDI

    ID: E-GEOD-47054

    Date Released: 12-26-2015

    Description: Cell-specific gene expression is achieved by a combination of mechanisms including transcriptional and post-transcriptional regulation. The transcript...

  9. Synergistic activity of BET protein antagonist-based combinations in Mantle Cell Lymphoma cells sensitive or resistant to ibrutinib OmicsDI

    ID: E-GEOD-70651

    Date Released: 01-02-2016

    Description: To determine the global transcriptome changes in mantle cell lymphoma cells following treatment with the BET bromodomain antagonist, JQ1 Mantle Cell L...

  10. Hormetic shifting of redox environment by the ROS-producing polyphenol resveratrol protects cells from oxidative stress OmicsDI

    ID: E-GEOD-72119

    Date Released: 01-02-2016

    Description: Resveratrol is a natural product that has gained tremendous interest due to multiple reported health-beneficial effects. However, the underlying mecha...

  11. CodeLink Mouse Whole Genome Bioarray data from hematopoietic stem cells (HSCs) of miR-125a (+/+) wild-type and miR-125a knockout mice with myeloprolif... OmicsDI

    ID: E-GEOD-69621

    Date Released: 01-01-2016

    Description: miR-125a knockout mice develop myeloproliferative disorder (MPD). To investigate the molecular mechanisms of MPD induced by the loss of miR-125a, gene...

  12. Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells OmicsDI

    ID: E-GEOD-66796

    Date Released: 12-26-2015

    Description: The human liver contains multiple cell types whose epigenetic patterns are undetermined. We examined the promoter methylome of purified and uncultured...

  13. Gene expression of 7 day combinatorial yohimbine and imipramine treated rat hippocampi OmicsDI

    ID: E-GEOD-61301

    Date Released: 01-03-2016

    Description: Rats treated on 7 consecutive days with either 2 injections of vehicle (Ctl) (DMSO for yohimbine, saline for imipramine) or Y+I (2mg/kg Yohimbine + 20...

  14. Cumulative low doses of the organic pesticide rotenone in the adult rat substantia nigra pars compacta OmicsDI

    ID: E-GEOD-22364

    Date Released: 01-02-2016

    Description: Adult male Sprague Dawley rats (5 month-old at the beginning of the study) were subcutaneously exposed to 0.5 mg.kg/d rotenone or the corresponding so...

  15. Global Analysis of the Transcriptional Response of Chinese cabbage (Brassica rapa ssp. pekinensis) to Methyl Jasmonate Reveals JA Signaling on Enhance... OmicsDI

    ID: E-GEOD-51363

    Date Released: 01-03-2016

    Description: We conducted a RNA-Seq analysis of MeJA-treated Chinese cabbage leaf transcriptome. Total 14,619,469 sequence reads were generated to produce 27,461 d...

  16. Gene expression changes in Apc-mutant mouse intestinal organoids 7 and 20 days after the induction of the Apc deletion OmicsDI

    ID: E-GEOD-47569

    Date Released: 01-02-2016

    Description: We isolated and selected intestinal adenoma organoids from Lgr5-EGFP-IRES-CreER; Apcflox/flox mice and added tamoxifen to induce the deletion of the A...

  17. 5-Day Gavage Study of Propylene glycol phenyl ether (PPH; CASRN 770-35-4) in Male Harlan Sprague Dawley Rats OmicsDI

    ID: E-GEOD-75656

    Date Released: 01-02-2016

    Description: The goal of this study was to characterize the potential toxicity and genomic benchmark dose of propylene glycol phenyl etherl in liver and kidney of...

  18. Integrating high-dimensional transcriptomics and image analysis tools into early safety screening (I) OmicsDI

    ID: E-GEOD-70611

    Date Released: 01-02-2016

    Description: In this paper we demonstrated the potential to flag toxicity issues by utilizing data from exploratory experiments which are typically generated for t...

  19. Genome-wide mapping of TEL-AML1 targets in acute leukemia OmicsDI

    ID: E-GEOD-67519

    Date Released: 01-03-2016

    Description: Around 20-25% of childhood acute lymphoblastic leukemias carry the TEL-AML1 (TA) fusion gene. It is a fusion of two central hematopoietic transcriptio...

  20. Transcription profiling by high throughput sequencing of Arabidopsis estradiol-inducible tor-es mutant OmicsDI

    ID: E-MTAB-4132

    Date Released: 01-04-2016

    Description: To validate that the transcriptional program rapidly activated by PP242, WYE354, KU63794 and Torin2 was specifically associated with the complete inhi...


Displaying 20 of 78,352 results for " "