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  1. Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity ArrayExpress

    ID: E-GEOD-61991

    Description: Circular RNAs (circRNAs), formed by the atypical head-to-tail splicing of exons, have re-emerged as a potentially interesting RNA species given recent...

  2. Widespread rearrangement of 3D chromatin organization underlies Polycomb-mediated stress-induced silencing [Hi-C] ArrayExpress

    ID: E-GEOD-63515

    Description: Chromosomes of metazoan organisms are partitioned in the interphase nucleus into discrete topologically associating domains (TADs). Borders between TA...

  3. Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression ArrayExpress

    ID: E-GEOD-66177

    Description: Akt is a robust oncogene that plays key roles in the development and progression of many cancers, including glioma. We evaluated the differential prop...

  4. Transcriptional response in mouse thyroid tissue after 211At administration: effects of absorbed dose, initial dose-rate and time after administration ArrayExpress

    ID: E-GEOD-66089

    Description: Transcriptomic profiling of normal mouse thyroid tissue following 211At irradiation Introduction The cellular response to stimuli can be studied on ...

  5. Role of Notch receptors in ozone induced lung injury in mice ArrayExpress

    ID: E-GEOD-58244

    Description: Ozone is a highly toxic air pollutant and global health concern. Mechanisms of genetic susceptibility to ozone-induced lung inflammation are not comp...

  6. Overexpression of miR-155 enhances B-cell lymphoma growth by targeting TBRG1 ArrayExpress

    ID: E-GEOD-64484

    Description: MYC regulates the expression of multiple microRNA (miRNA) genes and defines the Burkitt lymphoma (BL) miRNA signature. Here, we investigate the role o...

  7. Effects of thyroxine on the Craniosynostotic Phenotype ArrayExpress

    ID: E-GEOD-66149

    Description: Thyroid hormone is know to effect growth and development. However little is know about the hormone thyroxine's effect on craniofacial growth and sutur...

  8. Affymetrix SNP array data for NF1-associated glioma risk ArrayExpress

    ID: E-GEOD-62215

    Description: We performed whole genome SNP profiling on DNA samples from 236 patients with NF1, 123 with glimoa tumors and 113 without; 117 females and 119 males, ...

  9. Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice ArrayExpress

    ID: E-GEOD-65993

    Description: Calorie restriction is known to extend lifespan among organisms by a debating mechanism underlying nitric oxide-driven mitochondrial biogenesis. We re...

  10. Expression data from MDA-MB-231 breast cancer cell lines exposed to DMSO control and UF010 ArrayExpress

    ID: E-GEOD-56823

    Description: Breast cancer cell line MDA-MB-231 was treated with DMSO or UF010, a novel HDAC inhibitor for 24 hours. The impact of UF010 treatment on global gene e...

  11. High-throughput RNA sequencing of methanosarcina grown on methylated sulfur compounds ArrayExpress

    ID: E-GEOD-64349

    Description: Methylated sulfur compounds, including dimethylsulfide (DMS), methylmercaptopropionic acid (MMPA) and methylsulfide (MeSH), are well-documented to pla...

  12. Scml2 establshes germline-sepcific epigenome ArrayExpress

    ID: E-GEOD-55060

    Description: we identify Scml2, a subunit of a germ cell-specific polycomb repressive complex 1 (PRC1), as a critical epigenetic modifier that establishes the germ...

  13. The Nicotinic alpha6 Subunit Gene Determines Variability in Chronic Pain Sensitivity and Nicotine Anti- allodynia via Cross-inhibition of P2X2/3 Recep... ArrayExpress

    ID: E-GEOD-65997

    Description: We used microarray-based expression genomics in 25 inbred mouse strains to identify dorsal root ganglion (DRG)-expressed genetic contributors to mecha...

  14. Transgenerational Gene Expression Changes Caused by Exposing Fetal Germ Cells to Endocrine Disruptors ArrayExpress

    ID: E-GEOD-58642

    Description: We treated gestating female mice with vinclozolin (VZ), bisphenol A (BPA), di-(2-ethylhexyl) phthalate (DEHP), or control oil, during the time when th...

  15. Genome-wide profiling of miRNA expression dynamics in monocyte-derived dendritic cells following infection with a panel of intra-cellular bacteria ArrayExpress

    ID: E-GEOD-64142

    Description: We report the application of RNA sequencing to assess the expression dynamics of miRNAs and their isoforms over time upon infection with a panel of si...

  16. Identification of active transcriptional regulatory elements with GRO-seq ArrayExpress

    ID: E-GEOD-66031

    Description: Transcriptional regulatory elements (TREs), including enhancers and promoters, determine the transcription levels of associated genes. We have recent...

  17. Transcription factor binding dynamics during human ES cell differentiation ArrayExpress

    ID: E-GEOD-61475

    Description: Pluripotent stem cells provide a powerful system to dissect the underlying molecular dynamics that regulate cell fate changes during mammalian develop...

  18. The mammalian germline corrects deleterious effects of endocrine disruptors ArrayExpress

    ID: E-GEOD-59543

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  19. Gene expression analysis in differentiated day 3 cells from mouse ESC under the treatment of DMSO and histone deacetylase inhibitors (TSA) [expression... ArrayExpress

    ID: E-GEOD-66026

    Description: Based on the cDNA microarrays performed with the RNAs prepared from the differentiated cells at day 3 with or without 24 hrs TSA treatment initiated a...

  20. U937 scramble vs shHDAC2 upon SAHA (Vorinostat; suberoylanilide hydroxamic acid) treatment ArrayExpress

    ID: E-GEOD-37529

    Description: Transcriptional profiling of U937 scramble vs shHDAC2 before and after SAHA treatment at 5µM concentration for 6 and 24 hours. Different Experimental...


Displaying 20 of 2,122,300 results for " "