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  1. Natural Variation in Fish Transcriptomes: Comparative Analysis of the Fathead Minnow (Pimephales promelas) and Zebrafish (Danio rerio) OmicsDI

    ID: E-GEOD-60202

    Date Released: 08-19-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  2. Dazl is required for TET-mediated reprogramming to a naïve pluripotent state (I) OmicsDI

    ID: E-GEOD-69055

    Date Released: 08-19-2015

    Description: Embryonic stem cell (ESC) cultures display a heterogeneous gene expression profile, ranging from a pristine naïve pluripotent state to a primed epibl...

  3. Gata6 potently initiates reprogramming of pluripotent and differentiated cells to extraembryonic endoderm stem cells [time-course microarray] OmicsDI

    ID: E-GEOD-69321

    Date Released: 08-19-2015

    Description: Transcription factor-mediated reprogramming is a powerful method to study cell fate changes. In this work, we demonstrate that the transcription facto...

  4. E. histolytica and E. invadens OmicsDI

    ID: E-GEOD-67232

    Date Released: 08-19-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  5. Expression data from primary human mammary fibroblasts purified from disease-free women of low and high mammographic density OmicsDI

    ID: E-GEOD-38506

    Date Released: 08-18-2015

    Description: Although high mammographic density (MD) is considered one of the strongest risk factors for invasive breast cancer, the genes involved in modulating t...

  6. Gene expression profile of hemocytes from Manila clam (Venerupis philippinarum) after a Perkinsus olseni challenge using an immune-enriched oligo-micr... OmicsDI

    ID: E-GEOD-59399

    Date Released: 08-19-2015

    Description: Parasites of the genus Perkinsus spp. cause high mortalities and economic losses to the most noticeable bivalves produced in the worldwide aquaculture...

  7. A DNA Hypomethylation Signature Predicts Novel Anti-Tumor Activity of LSD1 Inhibitors in SCLC (ChIP-Seq) OmicsDI

    ID: E-GEOD-66297

    Date Released: 08-19-2015

    Description: Epigenetic dysregulation has emerged as an important mechanism in cancer. Alterations in epigenetic machinery have become a major focus for new targe...

  8. Tbx3 controls Dppa3 levels to regulate exit from pluripotency towards mesodermal lineage OmicsDI

    ID: E-GEOD-60066

    Date Released: 08-19-2015

    Description: Tbx3, a member of the T-box family, plays important roles in development, stem cells, nuclear reprogramming and cancer. Loss of Tbx3 induces different...

  9. Aberrant ERK signaling causes resistance to EGFR kinase inhibitors OmicsDI

    ID: E-GEOD-37699

    Date Released: 08-18-2015

    Description: The clinical efficacy of EGFR kinase inhibitors is limited by the development of drug resistance. The irreversible EGFR kinase inhibitor WZ4002 is eff...

  10. Gene expression profiling of human Ewing sarcoma cells after knockdown of EGR2 or EWSR1-FLI1. OmicsDI

    ID: E-GEOD-62090

    Date Released: 08-19-2015

    Description: To get insight in the functional role of EGR2 for Ewing sarcoma, we performed a transcriptional profiling of Ewing sarcoma cells after knockdown of EG...

  11. Effect of type 2 diabetes on transcriptional signatures during exercise and recovery OmicsDI

    ID: E-GEOD-59363

    Date Released: 08-19-2015

    Description: We performed gene expression microarray analysis of skeletal muscle biopsies from normal glucose tolerant subjects and type 2 diabetes subjects obtain...

  12. Expression data analyzed with LPIA in A549 lung carcinoma cells treated with geldanamycin. OmicsDI

    ID: E-GEOD-26525

    Date Released: 08-11-2015

    Description: The statsitcal model, latent pathway identification analysis (LPIA), was implemented for the analysis of A549 lung carcinoma cells treated with geldan...

  13. Exon expression for NCI Sarcoma cell line panel OmicsDI

    ID: E-GEOD-68591

    Date Released: 08-19-2015

    Description: Characterization of 68 cell lines derived from human sarcoma and 5 normal counterpart cells, including drug sensitivity testing, gene expression prof...

  14. System-Wide Analysis Reveals a Complex Network of Tumor-Fibroblast Interactions Involved in Tumorigenicity OmicsDI

    ID: E-GEOD-41678

    Date Released: 08-19-2015

    Description: We’ve undertaken a genome-wide approach to identify and test genes in fibroblasts that are both induced upon interaction with basal breast cancer ce...

  15. Conversion of MyoD to a neurogenic factor: binding site specificity determines lineage [RNA-seq] OmicsDI

    ID: E-GEOD-64622

    Date Released: 08-19-2015

    Description: MyoD and NeuroD2 are master regulators of myogenesis and neurogenesis and bind to a "shared" E-box sequence (CAGCTG) and a "private&quo...

  16. Small RNAs during E. histolytica stress response OmicsDI

    ID: E-GEOD-67230

    Date Released: 08-19-2015

    Description: We analyzed ~27nt small RNAs from Entamoeba histolytica trophozoites in basal conditions and after heat shock or oxidative stress E. histolytica troph...

  17. Genome-wide expression of the leukemic cells with different sensitivity to AraC OmicsDI

    ID: E-GEOD-59420

    Date Released: 08-19-2015

    Description: To examine the molecular alterations in cells with different sensitivity, genome-wide expression of the leukemic cells was profiled, revealing that ov...

  18. CGH analyses for the Chinese indigenous pig breeds and commercial pig breeds [Agilent] OmicsDI

    ID: E-GEOD-49299

    Date Released: 08-19-2015

    Description: Since CNVs play a vital role in genomic studies, it is an imperative need to develop a comprehensive, more accurate and higher resolution porcine CNV ...

  19. Germline duplication of ATG2B and GSKIP predisposes to familial essential thrombocythemia rapidly progressing to acute leukemia OmicsDI

    ID: E-GEOD-67938

    Date Released: 08-19-2015

    Description: No major predisposing gene for familial myeloproliferative neoplasms (MPN) has been identified. Here, we demonstrate that the autosomal dominant trans...

  20. Integrative ‘omic analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from SIRS OmicsDI

    ID: E-GEOD-59075

    Date Released: 08-19-2015

    Description: Rationale: Sepsis is a leading cause of morbidity and mortality; early diagnosis and prediction of progression is difficult to determine. The integrat...

  21. Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias [Patient samples] OmicsDI

    ID: E-GEOD-66291

    Date Released: 08-19-2015

    Description: Multiple myeloma (MM) is a malignant disorder characterized by the clonal proliferation of plasma cells (PCs) in the bone marrow (BM). The genetic bac...

  22. Assessment of MEK-ERK pathway targeting by BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias [U266 human myeloma cell line] OmicsDI

    ID: E-GEOD-66292

    Date Released: 08-19-2015

    Description: Multiple myeloma (MM) is a malignant disorder characterized by the clonal proliferation of plasma cells (PCs) in the bone marrow (BM). The genetic bac...

  23. Gene expression profile in MCF7 breast cancer cells after siRNA knock down of estrogen receptor alpha (ESR1) OmicsDI

    ID: E-GEOD-37820

    Date Released: 08-18-2015

    Description: Affymetrix microarray data was generated from MCF7 breast cancer cells treated in vitro with siRNAs against estrogen receptor alpha (ESR1). Gene expre...

  24. CD8 in vitro CD2-costimulation OmicsDI

    ID: E-MTAB-3470

    Date Released: 08-12-2015

    Description: Purified primary human CD8 T cells were stimulated in vitro in parallel using a magnetic bead conjugated to either anti-CD3/28 or anti-CD2/3/28 antibo...

  25. Hepatic miRNA profiles and thyroid hormone homeostasis in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS) [miRNA] OmicsDI

    ID: E-GEOD-69521

    Date Released: 08-19-2015

    Description: Perfluorooctanesulfonate (PFOS) has been widely used in a variety of industrial and commercial applications as a surfactant and stain repellent. PFOS ...

  26. Fitness of natural Saccharomyces cerevisiae strains [Expression] OmicsDI

    ID: E-GEOD-49549

    Date Released: 08-19-2015

    Description: To characterize the ecological interactions among S. cerevisiae strains coming from the same geographical area, we examined the fitness of two natural...

  27. Lung adenocarcinoma metastasis is suppressed by the alveolar lineage transcription factors GATA6 and HOPX. OmicsDI

    ID: E-GEOD-39121

    Date Released: 08-18-2015

    Description: Molecular programs that mediate normal cell differentiation are required for oncogenesis and tumor cell survival in certain types of cancers. How cell...

  28. Micro-array analysis of the anterior vaginal wall from premenopausal patients with Pelvic Organ Prolapse (POP) OmicsDI

    ID: E-GEOD-53868

    Date Released: 08-19-2015

    Description: Pelvic organ prolapse (POP) is a common multifactorial disease in a heterogeneous population of women. Due to this heterogeneity, the underlying molec...

  29. Expression data from MDA-MB-231 cell line treated with Zoledronate, or Fluvastatin, or mock-treated control cells. OmicsDI

    ID: E-GEOD-33552

    Date Released: 08-17-2015

    Description: Statins and bisphosponates (BPs) are two distinct classes of isoprenoid pathway inhibitors targeting HMG-CoA reductase (upstream enzyme) and Farnesyl-...

  30. Transcriptional profiling of clinically relevant SERMs and SERM/estradiol complexes in a cellular model of breast cancer OmicsDI

    ID: E-GEOD-35428

    Date Released: 08-17-2015

    Description: In this study, we have utilized microarray analysis to directly compare a subset of structurally distinct, clinically relevant SERMs in the presence a...

  31. Expression profile of A1-2 cells treated with 100 nM Dexamethasone or ethanol vehicle for 8h OmicsDI

    ID: E-GEOD-30592

    Date Released: 08-12-2015

    Description: A1-2 cells treated with 100 nM Dexamethasone or ethanol vehicle for 8h. The ability of steroid hormone receptors to initiate a genetic program is tigh...

  32. Transcription profiling by 3'-end sequencing of whole blood from pancreatic ductal adenocarcinoma (PDAC) patients and healthy controls for PDAC diagno... OmicsDI

    ID: E-MTAB-3823

    Date Released: 08-14-2015

    Description: We sequenced the transcriptomes using massive analysis of cDNA ends (MACE) of whole blood samples from 25 healthy volunteers and 47 PDAC patients to i...

  33. MeCP2 binds to mCH as neurons mature, influencing transcription and onset of Rett syndrome [Mnase-Seq] OmicsDI

    ID: E-GEOD-66869

    Date Released: 08-19-2015

    Description: The postnatal neurodevelopmental disorder Rett syndrome (RTT) is caused by mutations in the gene encoding Methyl-CpG-binding Protein 2 (MeCP2). Despit...

  34. Epigenomic Evolution of Diffuse Large B-cell Relapse OmicsDI

    ID: E-GEOD-66329

    Date Released: 08-19-2015

    Description: Here we characterize an association between disease progression and DNA methylation in Diffuse Large B cell Lymphoma (DLBCL). By profiling genome-wide...

  35. LEF-1 and TCF-1 orchestrate T follicular helper (Tfh) cell differentiation by regulating Tfh differentiation circuits upstream of Bcl6 OmicsDI

    ID: E-GEOD-67336

    Date Released: 08-19-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  36. Microarray analysis of gene expression changes in human A549 lung cancer cells upon siRNA knockdown of FAM60A and SDS3 OmicsDI

    ID: E-GEOD-39733

    Date Released: 08-18-2015

    Description: The Sin3 histone deacetylase (HDAC) complex is a 1.2 MDa chromatin modifying complex that can repress transcription by binding to gene promoters and d...

  37. Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of Trophoblast Stem Cells OmicsDI

    ID: E-MTAB-3565

    Date Released: 08-18-2015

    Description: Derivation and maintenance of TS cells depends on the presence of Fgf signalling. Numerous gene knock-out experiments identified the mitogen activated...

  38. Expression data from breast cancer tumor-initiating cells OmicsDI

    ID: E-GEOD-32526

    Date Released: 08-14-2015

    Description: We have generated tumorigenic (S2N) and non-tumorigenic (S2), normal-like to basal-like breast cancer cell lines from primary tumors. At high in vivo ...

  39. Expression data from knockdown of G9a in MDA-MB231 cells OmicsDI

    ID: E-GEOD-34925

    Date Released: 08-17-2015

    Description: G9a is an H3K9m2 methyltransferase, which is critical in controlling gene suppression and DNA methylation. We used microarray analysis to identify the...

  40. High-throughput sequencing of mouse liver transcriptome in Clock mutant animals OmicsDI

    ID: E-GEOD-41082

    Date Released: 08-19-2015

    Description: Circadian profile of polyA RNA by RNA-Seq, collected from ClockΔ19 mouse liver at CT22, CT28, CT34, CT40. RNA from three livers pooled per time point...

  41. RNA-Seq profiling of single bovine oocyte transcript abundance and its modulation by cytoplasmic polyadenylation OmicsDI

    ID: E-GEOD-61717

    Date Released: 08-19-2015

    Description: Polyadenylated RNA from individual germinal vesicle and metaphase II ooyctes was amplified and processed for Illumina sequencing. Increases in polyade...

  42. Molecular anatomy of palate development OmicsDI

    ID: E-GEOD-67525

    Date Released: 08-19-2015

    Description: Background: The FACEBASE consortium was established in part to create a central resource for craniofacial researchers. One purpose is to provide a mol...

  43. Transciptional response to acute thermal stress in Chinook salmon OmicsDI

    ID: E-GEOD-59756

    Date Released: 08-19-2015

    Description: Thermal stress is a serious and growing challenge facing Chinook salmon (Oncorhynchus tshawytscha) living in the southern portion of their native rang...

  44. Interactions of melanoma cells with distal keratinocytes trigger metastasis via Notch signaling inhibition of MITF OmicsDI

    ID: E-GEOD-69403

    Date Released: 08-19-2015

    Description: The most critical stage in initiation of melanoma metastasis is the radial to vertical growth transition, yet the triggers of this transition remain e...

  45. A Myc transcriptional program that is independent of EMT drives a poor prognosis tumor-propagating phenotype in HER2+ breast cancer OmicsDI

    ID: E-GEOD-43730

    Date Released: 08-19-2015

    Description: The HER2 (ERBB2) and MYC genes are commonly amplified genes in breast cancer, yet little is known about their molecular and clinical interaction. Usin...

  46. Gene expression alterations in human colon cancer xenograft treated with anti-VEGF antibody OmicsDI

    ID: E-GEOD-47087

    Date Released: 08-18-2015

    Description: Recent randomized clinical trial revealed the additional effect of bevacizumab, a humanized monoclonal antibody against vascular endothelial growth fa...

  47. Molecular changes induced in melanoma cells by stromal cells and anti-BRAF therapy. OmicsDI

    ID: E-GEOD-67637

    Date Released: 08-19-2015

    Description: Tumor-associated stromal cells can enable cancer cells to become insensitive to therapy. They can promote aggressive phenotype in cancer cells, which ...

  48. Expression profile of U373 cells over-expressing DTX1 and cells expressing a dominant negative form of MAML1 OmicsDI

    ID: E-GEOD-22772

    Date Released: 08-10-2015

    Description: Glioblastoma multiforme (GBM) is the most malignant and most common tumor of the central nervous system characterized by rapid growth and extensive ti...

  49. Networking of differentially expressed genes in human MCF7 breast cancer cells resistant to methotrexate OmicsDI

    ID: E-GEOD-16070

    Date Released: 08-06-2015

    Description: A summary of the work associated to these microarrays is the following: The need for an integrated view of all data obtained from high-throughput tec...

  50. Expression data from human skin exposed to solar-simulated radiation with or without sunscreen OmicsDI

    ID: E-GEOD-22083

    Date Released: 08-10-2015

    Description: Despite widespread use of sunscreens that minimize erythema by blocking ultraviolet B (UVB) radiation, incidence rates of melanoma continue to rise. ...


Displaying 50 of 78,256 results for " "