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  1. Increased DNA Methylation of Dnmt3b-Targets Impairs Leukemogenesis (expression) ArrayExpress

    ID: E-GEOD-71040

    Description: Here, we analyzed global gene expression changes that were associated with over expression of Dnmt3b in MLL-AF9 induced leukemias using the Affymetrix...

  2. Alternative cleavage and polyadenylation in spermatogenesis coordinates chromatin regulation and post-transcriptional control ArrayExpress

    ID: E-GEOD-73973

    Description: Most mammalian genes display alternative cleavage and polyadenylation (APA). Previous studies have indicated preferential expression of APA isoforms w...

  3. Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphoma ArrayExpress

    ID: E-GEOD-63265

    Description: Aggressive double and triple hit (DH/TH) DLBCL feature activation of Hsp90 stress pathways. Herein, we show that Hsp90 controls post-transcriptional ...

  4. The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Dot1l ko RNA-seq] ArrayExpress

    ID: E-GEOD-76748

    Description: Purpose: To characterize transcriptional changes associated with homozygous inactivation of Dot1l or Mll1 in MN1 driven AML Methods: We sequenced mRNA...

  5. MDM33 overexpression suppressor screen ArrayExpress

    ID: E-GEOD-49580

    Description: We performed a genome-wide screen for genetic MDM33 interaction partners. Using the opposite approach of the well known synthetic dosage lethality (sc...


Displaying 5 of 2,122,125 results for " "