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Displaying 20 of 2,122,300 results for " "
  1. Increased DNA Methylation of Dnmt3b-Targets Impairs Leukemogenesis (expression) ArrayExpress

    ID: E-GEOD-71040

    Description: Here, we analyzed global gene expression changes that were associated with over expression of Dnmt3b in MLL-AF9 induced leukemias using the Affymetrix...

  2. Alternative cleavage and polyadenylation in spermatogenesis coordinates chromatin regulation and post-transcriptional control ArrayExpress

    ID: E-GEOD-73973

    Description: Most mammalian genes display alternative cleavage and polyadenylation (APA). Previous studies have indicated preferential expression of APA isoforms w...

  3. Combinatorial targeting of nuclear export and translation of RNA inhibits aggressive B-cell lymphoma ArrayExpress

    ID: E-GEOD-63265

    Description: Aggressive double and triple hit (DH/TH) DLBCL feature activation of Hsp90 stress pathways. Herein, we show that Hsp90 controls post-transcriptional ...

  4. The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML [Mouse Dot1l ko RNA-seq] ArrayExpress

    ID: E-GEOD-76748

    Description: Purpose: To characterize transcriptional changes associated with homozygous inactivation of Dot1l or Mll1 in MN1 driven AML Methods: We sequenced mRNA...

  5. MDM33 overexpression suppressor screen ArrayExpress

    ID: E-GEOD-49580

    Description: We performed a genome-wide screen for genetic MDM33 interaction partners. Using the opposite approach of the well known synthetic dosage lethality (sc...

  6. microRNA expression in hematopoietic-associated populations differentiated from induced pluripotent stem cells ArrayExpress

    ID: E-GEOD-69503

    Description: In vitro generation of mature neutrophils from human induced pluripotent stem cells (iPSCs) requires hematopoietic progenitor development followed by ...

  7. The Histone Methyltransferases MLL1 and DOT1L Cooperate with Meningioma-1 to Induce AML ArrayExpress

    ID: E-GEOD-76750

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  8. Transcription profiling of human umbilical vein endothelial cells overexpressing constitutively active FOXO1 to identify FOXO1 target genes ArrayExpress

    ID: E-MTAB-4023

    Description: Adenoviral expression of a constitutive active FOXO1 vs. control GFP in human umbilical vein endothelial cells (HUVEC). Expression analysis 16 h after...

  9. Role of ST2 expession in regulatory Tcells on muscle regneration ArrayExpress

    ID: E-GEOD-76697

    Description: We describe the effects of Treg ST2 expression on muscle regeneration. We compare regneration from cryo-injured tibialis anterior muscle from Foxp3-C...

  10. Beta-catenin stabilization of skin fibroblasts causes fibrotic lesions by preventing adipocyte differentiation of the reticular dermis ArrayExpress

    ID: E-GEOD-76751

    Description: The Wnt/alpha-catenin pathway plays a central role in epidermal homeostasis and regeneration but how it affects fibroblast fate decisions is unknown. ...

  11. Transcriptome analysis upon SIN3 or dKDM5/LID knockdown or both under normal and paraquat induced stress conditions in Drosophila S2 cultured cells ArrayExpress

    ID: E-GEOD-68775

    Description: SIN3 the scaffold protein of a histone deacetylase complex interacts with a histone demethylase KDM5 (little imaginal discs - LID) in Drosophila. Redu...

  12. Gene expression analysis of untreated and NT-shRNA transduced kidney proximal tubular epithelial cells (PTECs) at day 6 and day 16 after transduction,... ArrayExpress

    ID: E-GEOD-72792

    Description: Primary kidney PTECs gradually became senescesince day 16, but SETD2 depletion prevented PTECs from senescence and maintained their proliferation beyo...

  13. Analysis of the role of Micu1 in maintaining functional homeostasis in mouse liver ArrayExpress

    ID: E-GEOD-69801

    Description: In this study, we analyzed global liver gene expression in MICU1 knock-down (KD) mice. To generate liver-specific MICU1 KD mice, MICU1loxp/loxp male m...

  14. The human cellular nucleic acid binding protien binds G-rich elements close to translation initiation sires and promotes translation. [RNA-Seq] ArrayExpress

    ID: E-GEOD-76627

    Description: CNBP is a eukaryote-conserved nucleic-acid binding protein required in mammals for embryonic development. It contains seven CCHC-type zinc-finger doma...

  15. Downstream genes regulated by TSHZ2 in MCF-7 cells ArrayExpress

    ID: E-GEOD-64351

    Description: To clarify downstream genes regulated by TSHZ2, MCF-7 cells were lentivirally transduced by TSHZ2 and its control LacZ and served their RNA samples fo...

  16. Expression data from rat orthotopic bladder cancer ArrayExpress

    ID: E-GEOD-76702

    Description: In the development and progression of bladder cancer, there are many genetic changes. We established a SD rat orthotopic bladder cancer model through ...

  17. Transcriptional reprogramming and resistance to colonic mucosal injury in PARP1-deficient mice ArrayExpress

    ID: E-GEOD-76658

    Description: Poly(ADP-ribose) polymerases (PARPs) synthesize and bind branched polymers of ADP-ribose to acceptor proteins using NAD as a substrate, ...

  18. Gene expression data from lung of mice infected with H5N1 or H1N1 virus ArrayExpress

    ID: E-GEOD-76719

    Description: To find the different host response during H5N1 and H1N1 infection, we have employed whole genome microarray expression profiling as a discovery platf...

  19. Identification of differentially expressed microRNAs between the fenpropathrin resistant and susceptible strains in Tetranychus cinnabarinus ArrayExpress

    ID: E-GEOD-76584

    Description: Purpose: The present study provides the firstly large-scale characterization of miRNAs in Tetranychus cinnabarinus and the comparison between fenpropa...

  20. Cell wall-deficient Mycoplasma hominis represses biofilm formation of uropathogenic Escherichia coli ArrayExpress

    ID: E-GEOD-43376

    Description: The features of Mycoplasma in human organ such lung and urinary tract are enigmatic. Here, the role of M. hominis in regard to biofilm formation of u...

Displaying 20 of 2,122,300 results for " "