KIAA1549 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search


If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on GitHub.

Displaying 2 of 2 results for "KIAA1549"
Switch View:
  1. Affymetrix SNP array data for low-grade astrocytoma samples

    ID: E-GEOD-14960

    Date Released: 05-04-2014

    Description: mour cDNA indentified a novel gene fusion between KIAA1549 and BRAF in these tumours. Copy number analysis of 21 paediatric low-grade astrocytomas using the Affymetrix GeneChip Human Mapping 250K Nsp Array. This study comprised 14 pilocytic astrocytomas, 4 diffuse astrocytomas, one pilomyxoid astrocytoma, one pilomyxoid glioma and one pleomorphic xanthoastrocytoma. Tumours were compared to the mean of...

  2. Rosette-forming glioneuronal tumour arising in the spinal cord: a case report and molecular profiling

    ID: E-GEOD-64891

    Date Released: 08-19-2015

    Description: 2) were identified. Additionally, we verified the KIAA1549-BRAF fusion, typically found in pilocytic astrocytomas, through aCGH, RT-PCR and FISH. Our comprehensive molecular profiling of a RGNT case suggests the existence of a unique genetic pathway for the development of these tumors: KIAA1549-BRAF fusion is a possible driver by constitutively activating MAPK pathway, and MLL2 mutation may lead to profound changes in the methylome. Taken together, these mechanisms may increase survival and/or tumorigenic capacity of cells, leading to the development of this rare entity. Two-color Agilent 8x60K array CGH (aCGH) was performed in the rosette-forming glioneuronal tumour (CY3) and reference DNA (CY5 - DNA extracted from leucocytes of the patient)....

Displaying 2 of 2 results for "KIAA1549"