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Displaying 4 of 4 results for "ZNF532"
  1. Identification of FOXO3 and PRDM1 as tumor suppressor gene candidates in NK cell neoplasms by the combination of genomic and functional analyses -CGH ArrayExpress

    ID: E-MEXP-3002

    Description: Array-CGH analysis of NK cell neoplasm (clinical samples + cell lines)

    dataAcquisition.name: Agilent Human Genome CGH Microarray 4x44K G4426B 014950 (85 rows x 532 cols)
  2. Classification of a frameshift/extended and a stop mutation in WT1 as gain of function mutations which activate cell cycle genes and promote Wilms tum... ArrayExpress

    ID: E-GEOD-54635

    Description: The Wilms tumor 1 (WT1) gene encodes a zinc finger transcription factor important for normal kidney development. WT1 is a suppressor for Wilms tumor de...

  3. CpG islands recruit a histone H3 lysine 36 demethylase [Agilent data] ArrayExpress

    ID: E-GEOD-21201

    Description: y depleted of this modification. KDM2A utilizes a zinc finger CxxC (ZF-CxxC) domain that specifically recognizes non-methylated CpG DNA and binding is blocked when the CpG DNA is methylated, thus constraining KDM2A to nonmethylated CpG islands. These data expose a remarkably straightforward mechanism through which KDM2A delineates a unique architecture that differentiates CpG island chromatin from bulk chromatin. Two cell lines were used in this study: a control line (LMP) with wildtype levels of KDM2A, and a KDM2A knockdown line (RNAi) in which KDM2A levels were depleted by approximately 60% using an shRNA-based approach. For each cell line, RNA was extracted from cells collected on two different dates (rep1 and rep2)....

  4. Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease ArrayExpress

    ID: E-GEOD-23766

    Description: enriched on chrY and chr19, where 11 male-biased zinc-finger KRAB-repressor domain genes are distributed in six clusters. Top biological functions and diseases significantly enriched in sex-biased genes include transcription, chromatin organization and modification, sexual reproduction, lipid metabolism and cardiovascular disease. Notably, sex-biased genes are enriched at loci associated with polygenic dyslipidemia and coronary artery disease in genome-wide association studies. Moreover, of the 8 sex-biased genes at these loci, 4 have been dir...

Displaying 4 of 4 results for "ZNF532"