ZBTB7A | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 20 results for "ZBTB7A"
i
  1. KLF1 directly activates expression of the novel fetal globin repressor, ZBTB7A/LRF, in erythroid cells BioProject

    ID: PRJNA382629

    Keywords: Epigenomics

    Access Type: download

  2. The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin BioProject

    ID: PRJNA302116

    Keywords: Other

    Access Type: download

  3. Effects of Lrf (encoded by Zbtb7a) deletion on gene expression in mouse embryonic fibroblast (MEF) BioProject

    ID: PRJNA289350

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Expression data from control and LRF (leukemia/lymphoma related factor)-deficient mouse LT-HSCs OmicsDI

    ID: E-GEOD-41839

    Date Released: 11-08-2012

    Description: LRF, which is encoded by the ZBTB7A gene and formerly known as POKEMON (POK erythroid myeloid ontogenic factor), was originally identified as a PLZF (promyelocy...

  5. Effects of Lrf (encoded by Zbtb7a) deletion on gene expression in mouse embryonic fibroblast (MEF) ArrayExpress

    ID: E-GEOD-70680

    Description: LRF is reported as a transcription repressor, but its transcription target genes are not completely known We compared the gene expression difference b...

  6. The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin ArrayExpress

    ID: E-GEOD-74977

    Description: not fully understood. Here, we show that the LRF/ZBTB7A transcription factor is a potent repressor of HbF production. LRF inactivation derepresses embryonic/fetal _-globin expression in mouse and human adult erythroid cells. We employed genome-wide analysis of the transcriptome, chromatin accessibility and LRF occupancy sites, and demonstrate that LRF occupies the _-globin loci and maintains nucleosome density necessary for _-globin silencing. L...

  7. Expression data from control and LRF (leukemia/lymphoma related factor)-deficient mouse LT-HSCs ArrayExpress

    ID: E-GEOD-41839

    Description: LRF, which is encoded by the ZBTB7A gene and formerly known as POKEMON (POK erythroid myeloid ontogenic factor), was originally identified as a PLZF (promyelocy...

  8. Expression data from control and LRF (leukemia/lymphoma related factor)-deficient mouse LT-HSCs BioProject

    ID: PRJNA178296

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: LRF, which is encoded by the ZBTB7A gene and formerly known as POKEMON (POK erythroid myeloid ontogenic factor), was originally identified as a PLZF (promyelocy...
  9. The LRF/ZBTB7A transcription factor is a BCL11A-independent repressor of fetal hemoglobin OmicsDI

    ID: E-GEOD-74977

    Date Released: 01-24-2016

    Description: not fully understood. Here, we show that the LRF/ZBTB7A transcription factor is a potent repressor of HbF production. LRF inactivation derepresses embryonic/fetal _-globin expression in mouse and human adult erythroid cells. We employed genome-wide analysis of the transcriptome, chromatin accessibility and LRF occupancy sites, and demonstrate that LRF occupies the _-globin loci and maintains nucleosome density necessary for _-globin silencing. L...

  10. Effects of Lrf (encoded by Zbtb7a) deletion on gene expression in mouse embryonic fibroblast (MEF) OmicsDI

    ID: E-GEOD-70680

    Date Released: 08-20-2015

    Description: LRF is reported as a transcription repressor, but its transcription target genes are not completely known We compared the gene expression difference b...

  11. Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis ArrayExpress

    ID: E-GEOD-16594

    Description: . Moreover, we show that the transcription factor Zbtb7a occupies GATA-1-bound regions of some direct GATA-1 target genes, that the presence of SCL/TAL1 helps distinguish transcriptional activation versus repression, and that polycomb repressive complex 2 (PRC2) is involved in epigenetic silencing of a subset of GATA-1-repressed genes. These data provide insights into GATA-1-mediated gene regulation in vivo. Keywords: Gene regulation Examination of GATA-1 occupancy in MEL cell line....

  12. Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis BioProject

    ID: PRJNA116159

    Keywords: Epigenomics

    Access Type: download

    dataset.description: . Moreover, we show that the transcription factor Zbtb7a occupies GATA-1-bound regions of some direct GATA-1 target genes, that the presence of SCL/TAL1 helps distinguish transcriptional activation versus repression, and that polycomb repressive complex 2 (PRC2) is involved in epigenetic silencing of a subset of GATA-1-repressed genes. These data provide insights into GATA-1-mediated gene regulation in vivo. Keywords: Gene regulation Overall design: Examination of GATA-1 occupancy in MEL cell line....
  13. Crystal structure of the BTB domain from the LRF/ZBTB7 transcriptional regulator PDB

    ID: PDB:2NN2

    Description: Zinc finger and BTB domain-containing protein 7A

    gene.name: ZBTB7A, FBI1, LRF, ZBTB7
  14. Structure of the POZ domain of human LRF, a master regulator of oncogenesis PDB

    ID: PDB:2IF5

    Description: Zinc finger and BTB domain-containing protein 7A

    gene.name: ZBTB7A, FBI1, LRF, ZBTB7
  15. Genes Differentially Expressed as a Result of Enforced Pokemon Expression in MCF-7 cell ArrayExpress

    ID: E-GEOD-27442

    Description: Pokmeon is an oncogenic transcription factor involved in cell growth, differentiation, and oncogenesis,but its regulatory network in breast cancer cel...

  16. Effect of Th-POK deficiency on global gene expression in liver Va14i NKT cells ArrayExpress

    ID: E-GEOD-34179

    Description: We sought to identify genes regulated by the transcription factor Th-POK (Zbtb7b) in liver Va14i NKT cells, by RNA microarray analysis of global gene ...

  17. Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis OmicsDI

    ID: E-GEOD-16594

    Date Released: 05-01-2014

    Description: . Moreover, we show that the transcription factor Zbtb7a occupies GATA-1-bound regions of some direct GATA-1 target genes, that the presence of SCL/TAL1 helps distinguish transcriptional activation versus repression, and that polycomb repressive complex 2 (PRC2) is involved in epigenetic silencing of a subset of GATA-1-repressed genes. These data provide insights into GATA-1-mediated gene regulation in vivo. Keywords: Gene regulation Examination of GATA-1 occupancy in MEL cell line....

  18. Effect of Th-POK deficiency on global gene expression in liver Va14i NKT cells BioProject

    ID: PRJNA149691

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Genes Differentially Expressed as a Result of Enforced Pokemon Expression in MCF-7 cell BioProject

    ID: PRJNA137065

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. Nexus and data files for Pokemon Evolutionary Phylogeny Zenodo

    ID: doi:10.5281/ZENODO.61631

    Release Date: 09-06-2016

    Description: Data files associated with the following publication: Matan Shelomi, Andrew Richards, Ivana Li, Yukinari Okido. (2012) “A Phylogeny and Evolutionar...


Displaying 20 of 20 results for "ZBTB7A"