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Displaying 20 of 56 results for "XPA"
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  1. Transcriptional changes in the absence of nth-1, xpa-1 and nth-1;xpa-1 BioProject

    ID: PRJNA116301

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Expression changes in Caenorhabditis elegans xpa-1 mutant BioProject

    ID: PRJNA170380

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Expression changes in Caenorhabditis elegans xpa-1 mutant ArrayExpress

    ID: E-GEOD-39252

    Description: scriptional profiling of NER-deficient C. elegans xpa-1 mutant showed overrepresentation of genes involved in lifespan determination and upregulation of several oxidative stress response genes (Fensgard et al. Aging 2010). However, since an independent study performed by Boyd and coworkers (Boyd et al. Mut Res 2010) showed limited number of changes in xpa-1 mutant. Therefore to independently validate that transcriptome modulation does take place in xpa

  4. Transcription profiling of liver from Csbm/m/Xpa-/- knockout mice to investigate the effect of nucleotide excision repair pathway inactivation OmicsDI

    ID: E-MEXP-835

    Date Released: 07-28-2014

    Description: ER). Here, complete inactivation of NER in Csbm/m/Xpa-/- mutants causes a phenotype that reliably mimics the human progeroid CS syndrome. Newborn Csbm/m/Xpa-/- mice display attenuated growth, progressive neurological dysfunction, retinal degeneration, cachexia, kyphosis and die before weaning. To investigate whether a disturbance in growth and metabolis...

  5. INTERACTIONS OF HUMAN NUCLEOTIDE EXCISION REPAIR PROTEIN XPA WITH RPA70 AND DNA: CHEMICAL SHIFT MAPPING AND 15N NMR RELAXATION STUDIES PDB

    ID: PDB:1D4U

    Description: NUCLEOTIDE EXCISION REPAIR PROTEIN XPA (XPA-MBD)

  6. Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (human) BioProject

    ID: PRJNA239756

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Expression changes in Caenorhabditis elegans xpa-1 mutant OmicsDI

    ID: E-GEOD-39252

    Date Released: 06-02-2014

    Description: scriptional profiling of NER-deficient C. elegans xpa-1 mutant showed overrepresentation of genes involved in lifespan determination and upregulation of several oxidative stress response genes (Fensgard et al. Aging 2010). However, since an independent study performed by Boyd and coworkers (Boyd et al. Mut Res 2010) showed limited number of changes in xpa-1 mutant. Therefore to independently validate that transcriptome modulation does take place in xpa

  8. Transcription profiling of liver from Csbm/m/Xpa-/- knockout mice to investigate the effect of nucleotide excision repair pathway inactivation ArrayExpress

    ID: E-MEXP-835

    Description: ER). Here, complete inactivation of NER in Csbm/m/Xpa-/- mutants causes a phenotype that reliably mimics the human progeroid CS syndrome. Newborn Csbm/m/Xpa-/- mice display attenuated growth, progressive neurological dysfunction, retinal degeneration, cachexia, kyphosis and die before weaning. To investigate whether a disturbance in growth and metabolis...

  9. Solution structure of a ERCC1-XPA heterodimer PDB

    ID: PDB:2JNW

    Description: DNA excision repair protein ERCC-1, DNA-repair protein complementing XP-A cells

  10. Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (mouse) ArrayExpress

    ID: E-GEOD-55485

    Description: ial dysfunction in xeroderma pigmentosum group A (XPA), a nucleotide excision DNA repair disorder with severe neurodegeneration, in silico and in vivo. XPA deficient cells show defective mitophagy with excessive cleavage of PINK1 and increased mitochondrial memb...

  11. Transcription profiling by array of mouse livers (wildtype vs Xpa-/-p53+/-) to study gene expression changes to the chemical compound benzo[a]pyrene OmicsDI

    ID: E-MTAB-1247

    Date Released: 01-26-2015

    Description: Gene expression changes to the chemical compound BaP in livers of wildtype and Xpa-/-p53+/- mice

  12. Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (mouse) OmicsDI

    ID: E-GEOD-55485

    Date Released: 06-06-2015

    Description: ial dysfunction in xeroderma pigmentosum group A (XPA), a nucleotide excision DNA repair disorder with severe neurodegeneration, in silico and in vivo. XPA deficient cells show defective mitophagy with excessive cleavage of PINK1 and increased mitochondrial memb...

  13. Defective Mitophagy in XPA via PARP1 activation and NAD+/SIRT1-depletion: Implications for neurodegeneration (mouse) BioProject

    ID: PRJNA239755

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Structural insights into the recognition of cisplatin and AAF-dG lesions by Rad14 (XPA) PDB

    ID: PDB:5A3D

    Description: DNA REPAIR PROTEIN RAD14

  15. SOLUTION STRUCTURE OF THE DNA-AND RPA-BINDING DOMAIN OF THE HUMAN REPAIR FACTOR XPA, NMR, 1 STRUCTURE PDB

    ID: PDB:1XPA

    Description: XPA

  16. Transcription profiling by array of mouse hepatocytes from wild type and Xpa-/-p53+/- strains following exposure to benzo[a]pyrene ArrayExpress

    ID: E-TABM-1139

    Description: Gene expression changes to several concentrations of benzo[a]pyrene in primary hepatocytes of wildtype and Xpa-/-p53+/- mice

  17. Transcription profiling by array of mouse hepatocytes from wild type and Xpa-/-p53+/- strains following exposure to benzo[a]pyrene OmicsDI

    ID: E-TABM-1139

    Date Released: 05-02-2014

    Description: Gene expression changes to several concentrations of benzo[a]pyrene in primary hepatocytes of wildtype and Xpa-/-p53+/- mice

  18. DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage [N2, xpa-1] BioProject

    ID: PRJNA221372

    Keywords: Transcriptome or Gene expression

    Access Type: download

  19. Transcription profiling by array of mouse livers (wildtype vs Xpa-/-p53+/-) to study gene expression changes to the chemical compound benzo[a]pyrene ArrayExpress

    ID: E-MTAB-1247

    Description: Gene expression changes to the chemical compound BaP in livers of wildtype and Xpa-/-p53+/- mice

  20. Transcriptomic response of young adult N2, xpa1, and glp1 nematodes 3h after exposure to 50 J/m2 UVC radiation at 25°C BioProject

    ID: PRJNA114931

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: radiation in widltype (N2), DNA repair-deficient (xpa-1), and germ cell-deficient (glp-1) young adult nematodes. We were interested in the wildtype response to this stressor, and postulated that the early (3h post-exposure) diff...

Displaying 20 of 56 results for "XPA"