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Displaying 7 of 7 results for "VGLL4"
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  1. The effect of VGLL4 on HCT116 colorectal cancer cell line BioProject

    ID: PRJNA322256

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. VGLL4 is a novel regulator of survival in human embryonic stem cells BioProject

    ID: PRJNA190189

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. VGLL4 is a novel regulator of survival in human embryonic stem cells ArrayExpress

    ID: E-GEOD-44590

    Description: ction of human open reading frames. We identified Vestigial-like 4 (VGLL4), a co-transcriptional regulator with no previously described function in hESCs, as a positive regulator of survival in hESCs. Specifically, VGLL4 overexpression in hESCs significantly decreases cell death in response to dissociation stress. Additionally, VGLL4 overexpression enhances hESC colony formation from single cells. These effects may be attributabl...

  4. Crystal structure of the VGLL4-TEAD4 complex PDB

    ID: PDB:4LN0

    Description: Transcriptional enhancer factor TEF-3, Transcription cofactor vestigial-like protein 4

  5. VGLL4 is a novel regulator of survival in human embryonic stem cells OmicsDI

    ID: E-GEOD-44590

    Date Released: 06-02-2014

    Description: ction of human open reading frames. We identified Vestigial-like 4 (VGLL4), a co-transcriptional regulator with no previously described function in hESCs, as a positive regulator of survival in hESCs. Specifically, VGLL4 overexpression in hESCs significantly decreases cell death in response to dissociation stress. Additionally, VGLL4 overexpression enhances hESC colony formation from single cells. These effects may be attributabl...

  6. VGLL4_MOUSE UniProt:Swiss-Prot

    ID: Q80V24

    Description: Transcription cofactor vestigial-like protein 4 Phosphoserine Phosphoserine

  7. Genome-Wide Association Study of Anorexia Nervosa dbGaP

    ID: phs000679.v1.p1

    Description: 98, 2q31.1, LRP2, 0, 8.68E-06; rs6782029, 3p25.3, VGLL4, 0, 9.04E-06; rs512089, 9p21.3, ELAVL2, 47984, 9.85E-06; rs3808986, 11q24.3, APLP2, 29217, 9.92E-6]. CNV analyses were performed on 1015 AN cases and 3532 controls. Overall frequencies of common or rare CNVs were similar between cases and controls. Specific rare and large (>500 kb, <1%) CNVs of interest included deletion of a large (~1.4Mbp) region of chr13q12 found in 2 AN samples and at a 10 fold lower frequency in a large sample (72,918) of subjects containing the genes SGCG, SACS, TNFRSF19, MIPEP, PCOTH, C1QTNF9B, SPATA13, MIR2276, and C1QTNF9, and an overlapping deletion and a duplication observed in 3 AN samples overlapping the CNTN6 and CNTN4 genes. Partially overlapping ~ 30 kb duplications were seen in 12 AN cases and in 1 control at the CDC5L gene on chromosome 6. Partially overlapping deletion of the 3' half of the PSTPIP1 gene was seen in 5 AN cases and no controls. Finally, a ~ 60 kb deletion of the PLEC1 gene was observed in 5 AN cases and in none of 3532 controls. Discussion: This is the first GWAS of AN. These preliminary results are consistent with absence of a major gene effect in AN. These results are consistent with genetic risk conveyed by multiple common alleles of small effect, as well as some uncommon CNVs of potentially larger effect. None of the implicated genes has a clear role in eating behavior. It must be emphasized that these results are preliminary and an additional ~ 400 AN cases will be analyzed as time and resources permit. These results require confirmation through study of independent populations of AN women....

    Study Types: Case-Control


Displaying 7 of 7 results for "VGLL4"