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Displaying 11 of 11 results for "TUFM"
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  1. EFTU_CANLF UniProt:Swiss-Prot

    ID: P54835

    Description: Elongation factor Tu, mitochondrial

    gene.name: TUFM
  2. EFTU_RAT UniProt:Swiss-Prot

    ID: P85834

    Description: Mitochondrion Elongation factor Tu, mitochondrial tr-type G GTP GTP GTP G1 G2 G3 G4 G5 N6-acetyllysine N6-acetyllysine N6-acetyllysine Phosphothreonin...

    gene.name: Tufm
  3. EFTU_CHICK UniProt:Swiss-Prot

    ID: P84172

    Description: Mitochondrion Elongation factor Tu, mitochondrial tr-type G GTP GTP GTP G1 G2 G3 G4 G5

    gene.name: TUFM
  4. EFTU_MESAU UniProt:Swiss-Prot

    ID: P86251

    Description: Elongation factor Tu, mitochondrial GTP Phosphothreonine

    gene.name: TUFM
  5. Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence vari... ArrayExpress

    ID: E-GEOD-53351

    Description: 148 out of the GWAS-identified SNPs; for example, TUFM (P=3.3E-48) was identified for inflammatory bowel disease (early onset); ZFP90 (P=4.4E-34) for ulcerative colitis; and IDUA (P=2.2E-11) for Parkinson's disease. We identified four genes (P<2.0E-14) that might be related to three diseases and two hematological traits; each expression is regulated by trans-eQTLs on a different chromosome than the gene. The study subjects were 301 apparently healthy individuals residing in Nagahama City, Japan. Whole blood was collected from each participant when in a non-stimulated state....

  6. Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers ArrayExpress

    ID: E-GEOD-73103

    Description: 1L, ELP4, ITIH4, SEMA3G, POMC, ADCY3, SSPN, LGR4, TUFM, MIR4721, SULT1A1, SULT1A2, APOBR, CLN3, SPNS1,SH2B1, ATXN2L, and IL27). Interestingly, the associated SNPs are in known eQTLs for some of these genes. We also found that the 107 CpGs are enriched in enhancers in peripheral blood mononuclear cells. Finally, our results indicate that some of these associations are not be blood-specific as we successfully replicated four associations in skin fibroblasts. Conclusions: Our results strongly suggest that many obesity-associated SNPs are associated with proximal gene regulation, which was reflected by association of obesity risk allele genotypes with differential DNA methylation. This study highlights the importance of DNA methylation and other chromatin marks as a way to understand the molecular basis of genetic variants associated to human diseases and traits. Bisulphite converted DNA from 355 individuals aged 14-34 were hybridised to the Illumina Infinium 450k Human Methylation Beadchip....

  7. Crystal Structure of Bos taurus mitochondrial Elongation Factor Tu/Ts Complex PDB

    ID: PDB:1XB2

    Description: Mitochondrial Elongation factors Tu and Ts

    gene.name: TUFM
  8. Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence vari... BioProject

    ID: PRJNA231784

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 148 out of the GWAS-identified SNPs; for example, TUFM (P=3.3E-48) was identified for inflammatory bowel disease (early onset); ZFP90 (P=4.4E-34) for ulcerative colitis; and IDUA (P=2.2E-11) for Parkinson's disease. We identified four genes (P<2.0E-14) that might be related to three diseases and two hematological traits; each expression is regulated by trans-eQTLs on a different chromosome than the gene. Overall design: The study subjects were 301 apparently healthy individuals residing in Nagahama City, Japan. Whole blood was collected from each participant when in a non-stimulated state....
  9. Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers BioProject

    ID: PRJNA296032

    Keywords: Epigenomics

    Access Type: download

    dataset.description: 1L, ELP4, ITIH4, SEMA3G, POMC, ADCY3, SSPN, LGR4, TUFM, MIR4721, SULT1A1, SULT1A2, APOBR, CLN3, SPNS1,SH2B1, ATXN2L, and IL27). Interestingly, the associated SNPs are in known eQTLs for some of these genes. We also found that the 107 CpGs are enriched in enhancers in peripheral blood mononuclear cells. Finally, our results indicate that some of these associations are not be blood-specific as we successfully replicated four associations in skin fibroblasts. Conclusions: Our results strongly suggest that many obesity-associated SNPs are associated with proximal gene regulation, which was reflected by association of obesity risk allele genotypes with differential DNA methylation. This study highlights the importance of DNA methylation and other chromatin marks as a way to understand the molecular basis of genetic variants associated to human diseases and traits. Overall design: Bisulphite converted DNA from 355 individuals aged 14-34 were hybridised to the Illumina Infinium 450k Human Methylation Beadchip....
  10. Large-scale East-Asian eQTL mapping reveals novel candidate genes for LD mapping and the genomic landscape of transcriptional effects of sequence vari... OmicsDI

    ID: E-GEOD-53351

    Date Released: 06-28-2014

    Description: 148 out of the GWAS-identified SNPs; for example, TUFM (P=3.3E-48) was identified for inflammatory bowel disease (early onset); ZFP90 (P=4.4E-34) for ulcerative colitis; and IDUA (P=2.2E-11) for Parkinson's disease. We identified four genes (P<2.0E-14) that might be related to three diseases and two hematological traits; each expression is regulated by trans-eQTLs on a different chromosome than the gene. The study subjects were 301 apparently healthy individuals residing in Nagahama City, Japan. Whole blood was collected from each participant when in a non-stimulated state....

  11. Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers OmicsDI

    ID: E-GEOD-73103

    Date Released: 09-19-2015

    Description: 1L, ELP4, ITIH4, SEMA3G, POMC, ADCY3, SSPN, LGR4, TUFM, MIR4721, SULT1A1, SULT1A2, APOBR, CLN3, SPNS1,SH2B1, ATXN2L, and IL27). Interestingly, the associated SNPs are in known eQTLs for some of these genes. We also found that the 107 CpGs are enriched in enhancers in peripheral blood mononuclear cells. Finally, our results indicate that some of these associations are not be blood-specific as we successfully replicated four associations in skin fibroblasts. Conclusions: Our results strongly suggest that many obesity-associated SNPs are associated with proximal gene regulation, which was reflected by association of obesity risk allele genotypes with differential DNA methylation. This study highlights the importance of DNA methylation and other chromatin marks as a way to understand the molecular basis of genetic variants associated to human diseases and traits. Bisulphite converted DNA from 355 individuals aged 14-34 were hybridised to the Illumina Infinium 450k Human Methylation Beadchip....


Displaying 11 of 11 results for "TUFM"