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Displaying 20 of 2,995 results for "TP53"
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  1. Data from: TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants Dryad

    DateIssued: 09-26-2016

    Description: me encodes 20 copies of the tumor suppressor gene TP53 and that the increase in TP53 copy number occurred coincident with the evolution of large body sizes, the evolution of extreme sensitivity to genotoxic stress, and a hyperactive TP53 signaling pathway in the elephant (Proboscidean) lineage. Furthermore we show that several of the TP53 retrogenes (TP53RTGs) are transcribed and likely translated. Whi...

  2. Genomic profiling of TP53 and non-TP53 Li-Fraumeni syndrome tumors reveals hits in the p53 and overlapping pathways OmicsDI

    ID: E-GEOD-8798

    Date Released: 05-02-2014

    Description: cer syndrome. Most cases are due to mutations in TP53. CHK2 is a minor predisposing locus; we recently mapped a third locus to 1q23. In both TP53 and non-TP53 LFS, there is evidence for risk heterogeneity within and between kindreds...

  3. Compare proB cells from WT, Tp53-/-, Lnk-/-, Tp53-/-Lnk-/- mice and Tp53-/-Lnk-/-B-ALL OmicsDI

    ID: E-GEOD-76940

    Date Released: 04-11-2016

    Description: d that combined loss of Lnk and tumor suppressors Tp53 in mice triggers a highly aggressive and transplantable precursor B-ALL. This study aims to investigate the molecular mechanism by which LNK regulates B-ALL development. We performed expression profiling of bone marrow proB progenitors from WT, Tp53-/-, Lnk-/- and preleukemic healthy Tp53/Lnk double knockout (DKO) mice, as well as leukemic bone marrow cells from DKO mice that have developed B-ALL. Results suggest that

  4. TP53.nex Dryad

    DateIssued: 09-26-2016

    Description: Nexus file used in MrBayes

  5. TP53.phy Dryad

    DateIssued: 09-26-2016

    Description: .phy file used in PhyML

  6. TP53.xml Dryad

    DateIssued: 09-26-2016

    Description: .xml file used for BEAST

  7. Compare proB cells from WT, Tp53-/-, Lnk-/-, Tp53-/-Lnk-/- mice and Tp53-/-Lnk-/-B-ALL BioProject

    ID: PRJNA309083

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Genomic profiling of TP53 and non-TP53 Li-Fraumeni syndrome tumors reveals hits in the p53 and overlapping pathways BioProject

    ID: PRJNA102101

    Keywords: Variation

    Access Type: download

  9. TRIAA_XENLA UniProt:Swiss-Prot

    ID: Q6INR6

    Description: TP53-regulated inhibitor of apoptosis 1-A Important for interaction with prelid3a Important for interaction with prelid3a

  10. TRIAB_XENLA UniProt:Swiss-Prot

    ID: Q6DD38

    Description: TP53-regulated inhibitor of apoptosis 1-B Important for interaction with prelid3a Important for interaction with prelid3a

  11. Additional file 2: of TP53 gene mutation analysis in chronic lymphocytic leukemia by nanopore MinION sequencing Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3639701_D2

    Release Date: 12-15-2016

    Description: Reformatted file of â gene variation IARC TP53 databaseâ to use in Galaxy workflow for variants annotation. (TXT 1603 kb)

  12. Transcription profiling of human japanese breast cancer patients to predict breast cancer prognosis by gene expression profile of TP53 status. OmicsDI

    ID: E-GEOD-5546

    Date Released: 05-03-2014

    Description: TP53 mutations are a poor prognostic factor in breast cancers. This study sets out to identify the gene set that determine expressi...

  13. TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia [aCGH] OmicsDI

    ID: E-GEOD-60852

    Date Released: 09-07-2014

    Description: plasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational status confers ad...

  14. m237i1 Dryad

    DateIssued: 02-23-2015

    Description: The m237i p53 cancer mutant gene core domain sequence.

  15. TP53 mutational status is a potential marker for risk stratification in Wilms tumour with diffuse anaplasia [expression] OmicsDI

    ID: E-GEOD-60850

    Date Released: 09-07-2014

    Description: plasia in Wilms tumours (DAWT) is associated with TP53 mutations and poor outcome. As patients receive intensified treatment, we sought to identify whether TP53 mutational status confers ad...

  16. Genome sequencing of childhood medulloblastoma brain tumors links chromothripsis with TP53 mutations OmicsDI

    ID: E-GEOD-34258

    Date Released: 05-04-2014

    Description: HH-MB) brain tumor from a patient with a germline TP53 mutation (Li-Fraumeni syndrome) revealed massive, complex rearrangements resulting from chromothripsis. Integrating TP53 status with genomic rearrangement data in additional medulloblastomas revealed a striking association between TP53 mutation and chromothripsis in SHH-MBs. Unexpectedly, five seemingly sporadic SHH-MB patients with chromothripsis harbored TP53 germline mutations – fi...

  17. T53G5_HUMAN UniProt:Swiss-Prot

    ID: Q9Y2B4

    Description: TP53-target gene 5 protein In dbSNP:rs2231616. In dbSNP:rs2231619. In dbSNP:rs2231620. In dbSNP:rs2231622. In dbSNP:rs2231623. In d...

  18. TRIA1_XENTR UniProt:Swiss-Prot

    ID: A9ULB4

    Description: TP53-regulated inhibitor of apoptosis 1 Important for interaction with prelid3a Important for interaction with prelid3a

  19. Crystal Structure a TP53-induced glycolysis and apoptosis regulator protein from Homo sapiens. PDB

    ID: PDB:3DCY

    Description: REGULATOR PROTEIN

  20. p53 haplotypes_Quina etal Dryad

    DateIssued: 05-22-2015

    Description: Sequence information of the p53 haplotypes found in Microtus duodecimcostatus and Microtus lusitanicus (Quina et al, 2015).


Displaying 20 of 2,995 results for "TP53"