TNFRSF13B | bioCADDIE Data Discovery Index
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Displaying 20 of 25 results for "TNFRSF13B"
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  1. The crystal structure of APRIL bound to TACI PDB

    ID: PDB:1XU1

    Description: Tumor necrosis factor ligand superfamily member 13,

  2. Solution structure of TACI-CRD2 PDB

    ID: PDB:1XUT

    Description: Tumor necrosis factor receptor superfamily

  3. Crystal structure of sTALL-1 and BCMA PDB

    ID: PDB:1OQD

    Description: Tumor necrosis factor ligand superfamily member

  4. Crystal structure of sTALL-1 with BAFF-R PDB

    ID: PDB:1OQE

    Description: Tumor necrosis factor ligand superfamily member

  5. Complex between BAFF and a BR3 derived peptide presented in a beta-hairpin scaffold PDB

    ID: PDB:1OSG

    Description: Tumor necrosis factor ligand superfamily member

  6. Homo sapiens : Screening of TNFRSF13B in a group of CVID and healthy controls in Sri Lanka BioProject

    ID: PRJNA268221

    Keywords: other

    Access Type: download

  7. Crystal structure of the BAFF-BAFF-R complex PDB

    ID: PDB:4V46

    Description: Tumor necrosis factor ligand superfamily member

  8. Time-course effect of APRIL on gene expression in HepG2 cells ArrayExpress

    ID: E-GEOD-29375

    Description: APRIL (TNFSF13) is a ligand of the TNF superfamily which binds to two receptors, BCMA and TACI. We have found that APRIL and its receptor

  9. microRNA-expression profile in a series of Nodal marginal zone lymphoma patients [miRNA expression] ArrayExpress

    ID: E-GEOD-32232

    Description: ls. The most highly overexpressed genes were SYK, TACI, CD74, CD82 and CDC42EP5. Genes linked to G2/M and germinal center were downregulated. Comparison of the gene expression profiles of NMZL and FL showed enriched expression of CHIT1 and TACI in NMZL, and BCL6, LMO2 and CD10 in FL. NMZL displayed increased expression of miR-223 and let-7f, while FL strongly expressed miR-494. Our study identifies new candidate diagnostic molecules for NMZL and reveals survival pathways activated in NMZL. microRNA-expression profiling was conducted in a series of 40 B-cell non-Hodgkin lymphoma patients (NMZL, and FL). Six lymph nodes with reactive lymphoid hyperplasia (RLN) were used as controls...

  10. Molecular characterization of Nodal marginal zone lymphoma [Gene Expression] BioProject

    ID: PRJNA154895

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ls. The most highly overexpressed genes were SYK, TACI, CD74, CD82 and CDC42EP5. Genes linked to G2/M and germinal center were downregulated. Comparison of the gene expression profiles of NMZL and FL showed enriched expression of CHIT1, TGFB1 and TACI in NMZL, and BCL6, LMO2 and CD10 in FL. NMZL displayed increased expression of miR-221, miR-223 and let-7f, while FL strongly expressed miR-494. Our study identifies new candidate diagnostic molecules for NMZL and reveals survival pathways activated in NMZL. Overall design: We have analyzed gene expression, miRNA profile and copy number data from 15 NMZL cases. For comparison, 16 follicular lymphomas, 9 extranodal marginal zone lymphomas, 8 reactive lymph nodes and B-cell subtypes were included. The results were validated by qRT-PCR in an independent series including 61 paraffin-embedded NMZLs...
  11. Molecular characterization of Nodal marginal zone lymphoma [CGH] ArrayExpress

    ID: E-GEOD-32436

    Description: ls. The most highly overexpressed genes were SYK, TACI, CD74, CD82 and CDC42EP5. Genes linked to G2/M and germinal center were downregulated. Comparison of the gene expression profiles of NMZL and FL showed enriched expression of CHIT1, TGFB1 and TACI in NMZL, and BCL6, LMO2 and CD10 in FL. NMZL displayed increased expression of miR-221, miR-223 and let-7f, while FL strongly expressed miR-494. Our study identifies new candidate diagnostic molecules for NMZL and reveals survival pathways activated in NMZL. Copy number alteration (CNA) was assayed with the DNA from 14 NMZL of frozen-tissue cases, extracted using the standard phenol-chloroform protocol. For CNA, the DNA was hybridized on an Agilent Human Genome CGH Microarray Kit 1 x 44K (Agilent Technologies) following the manufacturer’s instructions. Human female and male pooled gDNA (Promega) was used to normalize the CGH results. Results were consider...

  12. microRNA-expression profile in a series of Nodal marginal zone lymphoma patients [miRNA expression] BioProject

    ID: PRJNA154893

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ls. The most highly overexpressed genes were SYK, TACI, CD74, CD82 and CDC42EP5. Genes linked to G2/M and germinal center were downregulated. Comparison of the gene expression profiles of NMZL and FL showed enriched expression of CHIT1 and TACI in NMZL, and BCL6, LMO2 and CD10 in FL. NMZL displayed increased expression of miR-223 and let-7f, while FL strongly expressed miR-494. Our study identifies new candidate diagnostic molecules for NMZL and reveals survival pathways activated in NMZL. Overall design: microRNA-expression profiling was conducted in a series of 40 B-cell non-Hodgkin lymphoma patients (NMZL, and FL). Six lymph nodes with reactive lymphoid hyperplasia (RLN) were used as controls...
  13. Molecular characterization of Nodal marginal zone lymphoma [Gene Expression] ArrayExpress

    ID: E-GEOD-32231

    Description: ls. The most highly overexpressed genes were SYK, TACI, CD74, CD82 and CDC42EP5. Genes linked to G2/M and germinal center were downregulated. Comparison of the gene expression profiles of NMZL and FL showed enriched expression of CHIT1, TGFB1 and TACI in NMZL, and BCL6, LMO2 and CD10 in FL. NMZL displayed increased expression of miR-221, miR-223 and let-7f, while FL strongly expressed miR-494. Our study identifies new candidate diagnostic molecules for NMZL and reveals survival pathways activated in NMZL. We have analyzed gene expression, miRNA profile and copy number data from 15 NMZL cases. For comparison, 16 follicular lymphomas, 9 extranodal marginal zone lymphomas, 8 reactive lymph nodes and B-cell subtypes were included. The results were validated by qRT-PCR in an independent series including 61 paraffin-embedded NMZLs...

  14. Time-course effect of APRIL on gene expression in HepG2 cells BioProject

    ID: PRJNA140099

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: APRIL (TNFSF13) is a ligand of the TNF superfamily which binds to two receptors, BCMA and TACI. We have found that APRIL and its receptor
  15. Gene expression profile of the Myd88 gene depletion on mouse salivary glands ArrayExpress

    ID: E-GEOD-61339

    Description: ransduction downstream of Toll-like receptors and TACI, receptors for regulation of innate immunity and B cell responses, respectively. The surfaces of oral mucosa are protected from infections by antimicrobial proteins and natural...

  16. Classical and/or alternative NF-kB pathway activation in multiple myeloma pathogenesis BioProject

    ID: PRJNA119303

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: pathway, whereas several mutations (CYLD, NFKB1, TACI) selectively activate the classical pathway. However, most mutations affecting NIK level (NIK, TRAF2, TRAF3, cIAP1&2, CD40) activate the alternative but often both pathways. Second, we confirm the critical role of TRAF2 in regulating NIK degradation, whereas TRAF3 enhances but is not essential for cIAP1/2-mediated proteosomal degradation of NIK in MM. Third, using transfection to selectively activate the classical or alternative NFKB pathways, we show virtually identical changes in gene expression in one MMCL, whereas the changes are similar albeit non-identical in a second MMCL. Together, our results suggest that MM tumors can achieve increased auton...
  17. Molecular characterization of Nodal marginal zone lymphoma [CGH] BioProject

    ID: PRJNA154543

    Keywords: Variation

    Access Type: download

    dataset.description: ls. The most highly overexpressed genes were SYK, TACI, CD74, CD82 and CDC42EP5. Genes linked to G2/M and germinal center were downregulated. Comparison of the gene expression profiles of NMZL and FL showed enriched expression of CHIT1, TGFB1 and TACI in NMZL, and BCL6, LMO2 and CD10 in FL. NMZL displayed increased expression of miR-221, miR-223 and let-7f, while FL strongly expressed miR-494. Our study identifies new candidate diagnostic molecules for NMZL and reveals survival pathways activated in NMZL. Overall design: Copy number alteration (CNA) was assayed with the DNA from 14 NMZL of frozen-tissue cases, extracted using the standard phenol-chloroform protocol. For CNA, the DNA was hybridized on an Agilent Human Genome CGH Microarray Kit 1 x 44K (Agilent Technologies) following the manufacturer’s instructions. Human female and male pooled gDNA (Promega) was used to normalize the CGH results. Resul...
  18. Identification of stage specific genes associated with lupus nephritis and response to remission induction in NZB/W and NZM2410 mice BioProject

    ID: PRJNA215279

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: anti-CD154 (early and late after remission) or Ad-TACI-Ig+CTLA4Ig (late after remission) and NZM2410 treated with Ad-BAFF-R-Ig. Overall design: Expression data from lupus NZB/W mouse kidneys at 30 wks old and treated and from NZM2410 mouse kidneys treated. RNA from whole kidneys was extracted and processed for hybridization on Affymetrix microarrays....
  19. Gene expression profile of the Myd88 gene depletion on mouse salivary glands BioProject

    ID: PRJNA260811

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ransduction downstream of Toll-like receptors and TACI, receptors for regulation of innate immunity and B cell responses, respectively. The surfaces of oral mucosa are protected from infections by antimicrobial proteins and natural...
  20. Molecular characterization of Nodal marginal zone lymphoma [CGH] OmicsDI

    ID: E-GEOD-32436

    Date Released: 05-04-2014

    Description: ls. The most highly overexpressed genes were SYK, TACI, CD74, CD82 and CDC42EP5. Genes linked to G2/M and germinal center were downregulated. Comparison of the gene expression profiles of NMZL and FL showed enriched expression of CHIT1, TGFB1 and TACI in NMZL, and BCL6, LMO2 and CD10 in FL. NMZL displayed increased expression of miR-221, miR-223 and let-7f, while FL strongly expressed miR-494. Our study identifies new candidate diagnostic molecules for NMZL and reveals survival pathways activated in NMZL. Copy number alteration (CNA) was assayed with the DNA from 14 NMZL of frozen-tissue cases, extracted using the standard phenol-chloroform protocol. For CNA, the DNA was hybridized on an Agilent Human Genome CGH Microarray Kit 1 x 44K (Agilent Technologies) following the manufacturer’s instructions. Human female and male pooled gDNA (Promega) was used to normalize the CGH results. Results were consider...


Displaying 20 of 25 results for "TNFRSF13B"