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Displaying 20 of 291 results for "TLR7"
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  1. Crystal structure of monkey TLR7 in complex with loxoribine and polyU PDB

    ID: PDB:5GMG

    Description: Toll-like receptor 7/RNA Complex

  2. Crystal structure of monkey TLR7 in complex with guanosine and polyU PDB

    ID: PDB:5GMF

    Description: Toll-like receptor 7/RNA Complex

  3. Crystal structure of monkey TLR7 in complex with R848 PDB

    ID: PDB:5GMH

    Description: Toll-like receptor 7

  4. Toll-like receptor 7 is a primary sensor of malaria infection BioProject

    ID: PRJNA177224

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Toll-like receptor 7 is a primary sensor of malaria infection ArrayExpress

    ID: E-GEOD-41496

    Description: amplified total splenic RNA isolated from TLR9-, TLR7-, UNC93b1- or MYD88- deficient mice or their C57BL/6 controls 24h after mock infection or infection with Plasmodium chabaudi. 4 independent replicate...

  6. Dysregulated TLR7 signaling drives anemia via development of hemophagocytic macrophages ArrayExpress

    ID: E-GEOD-70520

    Description: us Erythematosus (SLE) is closely associated with Toll-like receptor (TLR) 7 and type I interferon (IFN) activity in humans and in murine SLE-like diseas...

  7. Dysregulated TLR7 signaling drives anemia via development of hemophagocytic macrophages BioProject

    ID: PRJNA288944

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Dysregulated TLR7 signaling drives anemia via development of hemophagocytic macrophages OmicsDI

    ID: E-GEOD-70520

    Date Released: 07-11-2016

    Description: us Erythematosus (SLE) is closely associated with Toll-like receptor (TLR) 7 and type I interferon (IFN) activity in humans and in murine SLE-like diseas...

  9. Sustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B ArrayExpress

    ID: E-GEOD-67935

    Description: ure. We evaluated whether the oral small molecule toll-like receptor (TLR7) agonist GS-9620 could induce durable anti-viral efficacy in woodchucks chronically infected with woodchuck hepatitis virus (WHV), a hepadnavirus closely related to human hep...

  10. Sustained Efficacy and Seroconversion with the Toll-Like Receptor 7 Agonist GS-9620 in the Woodchuck Model of Chronic Hepatitis B BioProject

    ID: PRJNA281246

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Suppression of molecular inflammatory pathways by Toll-like Receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation ArrayExpress

    ID: E-GEOD-50400

    Description: ent evidence suggests that abnormal activation of Toll-like receptors (TLRs) 7, 8 and 9 contributes to the initiation and maintenance of psoriasis. We have evaluated the effects of TLR antagonists on the gene expression profile in an IL-23-induced skin in...

  12. Suppression of molecular inflammatory pathways by Toll-like Receptor 7, 8, and 9 antagonists in a model of IL-23-induced skin inflammation BioProject

    ID: PRJNA217418

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. Gene expression profile of human antigen presenting cells with a tolerogenic phenotype BioProject

    ID: PRJNA385188

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: an early encounter of isolated monocytes with the Toll-like receptor 7/8 ligand R848 mediates a switch of pro-inflammatory to immunosupressive properties. We were strongly interested in the identification of factors that are involved in the differentiation of these t...
  14. Bruton's Tyrosine Kinase Regulates TLR9 but not TLR7 Signaling in Human pDCs BioProject

    ID: PRJNA178243

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. TLR signaling in C57BL/6J TLR7-tolerant CD3+ T-cells over B6 TLR7 null CD3+ T-cells. BioProject

    ID: PRJNA319333

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Bruton's Tyrosine Kinase Regulates TLR9 but not TLR7 Signaling in Human pDCs ArrayExpress

    ID: E-GEOD-41825

    Description: yrosine kinase (Btk) to the activation of pDCs by TLR7 and TLR9 stimulation by using a selective Btk inhibitor RN486. Stimulation of TLR7 and 9 with their respective agonist, namely, gardiquimod and type A CpG ODN2216, resulted in the activation of human pDCs, as demonstrated by the expression of activation markers (CD69, CD40, and CD86), elevated production of IFN-alpha and other inflammatory cytokines, as well as up-regulation of numerous genes including IFN-alpha-inducible genes and activation of interferon regulatory factor 7 (IRF7) and N...

  17. Crystal structure of human TLR8 in complex with DS-802 PDB

    ID: PDB:4QBZ

    Description: Toll-like receptor 8

  18. Crystal structure of human TLR8 in complex with XG-1-236 PDB

    ID: PDB:4QC0

    Description: Toll-like receptor 8

  19. Treatment of human monocytes with TLR7 or TLR8 agonists BioProject

    ID: PRJNA271093

    Keywords: Transcriptome or Gene expression

    Access Type: download

  20. Toll-like receptor 7 is a primary sensor of malaria infection OmicsDI

    ID: E-GEOD-41496

    Date Released: 06-02-2014

    Description: amplified total splenic RNA isolated from TLR9-, TLR7-, UNC93b1- or MYD88- deficient mice or their C57BL/6 controls 24h after mock infection or infection with Plasmodium chabaudi. 4 independent replicate...


Displaying 20 of 291 results for "TLR7"