THBD | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 78 results for "THBD"
i
  1. Gene expression in Mouse thrombomoudlin+ and thrombomodulin- dendritic cell BioProject

    ID: PRJNA195538

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Crystal Structure of Na-free Thrombin in Complex with Thrombomodulin PDB

    ID: PDB:3GIS

    Description: Prothrombin (E.C.3.4.21.5), Thrombomodulin

  3. Crystal structure of thrombin mutant W215A/E217A fused to EGF456 of thrombomodulin via a 31-residue linker and bound to PPACK PDB

    ID: PDB:5TO3

    Description: Prothrombin (E.C.3.4.21.5), Prothrombin,Thrombomodulin (E.C.3.4.21.5)

  4. Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal T cells via TGF-β ArrayExpress

    ID: E-GEOD-43184

    Description: s and humanized mice, the role of human CD1c+ and CD141+ DCs in determining the type of CD8+ T cell immunity to live-attenuated influenza virus (LAIV) vaccine. We found that both lung DC subsets acquired influenza antigens in vivo and expanded specific cytotoxic CD8+ T cells in vitro. However, lung-tissue-resident CD1c+ DCs but not ...

  5. NMR STRUCTURE OF THROMBOMODULIN EGF(4-5) PDB

    ID: PDB:1DQB

    Description: THROMBOMODULIN

  6. TRBM_MOUSE UniProt:Swiss-Prot

    ID: P15306

    Description: Thrombomodulin Extracellular Helical Cytoplasmic C-type lectin EGF-like 1 EGF-like 2 EGF-like 3; calcium-binding EGF-like 4 EGF-lik...

  7. FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, 14 STRUCTURES PDB

    ID: PDB:1ADX

    Description: THROMBOMODULIN

  8. Transcriptome profiles of mouse and human monocyte and dendritic cell subsets (human data) ArrayExpress

    ID: E-GEOD-35457

    Description: . Although recent evidence points to human blood CD141+ DCs as the functional equivalent of CD8+ DC, the precise identity of the human migratory cross-presenting DC has remained elusive. We performed phenotypic and functional analyses to interrogate the DC compartment of human non-lymphoid tissues and identified three distinct subsets: i) CD141high DCs, ii) CD1c DCs and iii) CD14+ DCs. Only CD141high DCs were capable of cross-presenting soluble antigen. Comparative transcriptome analysis of steady state monocyte and DC subsets between mouse ...

  9. Crystal structure of the thrombin-thrombomodulin complex PDB

    ID: PDB:1DX5

    Description: THROMBIN LIGHT CHAIN (E.C.3.4.21.5), THROMBIN INHIBITOR GLU-GLY-ARG-0QE, THROMBOMODULIN, THROMBIN HEAVY CHAIN (E.C.3.4.21.5)

  10. FOURTH EGF-LIKE DOMAIN OF THROMBOMODULIN, NMR, 12 STRUCTURES PDB

    ID: PDB:1ZAQ

    Description: THROMBOMODULIN

  11. Modular expression analysis reveals functional conservation between human Langerhans Cells and mouse cross-priming dendritic cells ArrayExpress

    ID: E-GEOD-66355

    Description: signature specific to the blood cross-presenting CD141/BDCA-3+ DCs, the proposed equivalent to mouse CD8α+ DCs. Consistent with our analysis, LCs were highly adept at inducing primary CTL responses. Thus, our study suggests that the function of LCs may not be conserved between mouse and human and supports human LCs as an especially relevant therapeutic target. RNA from sorted populations was purified using TRIzol. RNA was processed, amplified, labeled and hybridized at Washington University Core Facility (GTAC) with Illumina HumanHT-12 v4 Expression BeadChip. Data were background subtracted and quantile normalized....

  12. FIFTH EGF-LIKE DOMAIN OF THROMBOMODULIN (TMEGF5), NMR, MINIMIZED AVERAGE STRUCTURE PDB

    ID: PDB:2ADX

    Description: THROMBOMODULIN

  13. Human CD1c+ dendritic cells drive the differentiation of CD103+ CD8+ mucosal T cells via TGF-β BioProject

    ID: PRJNA184857

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: s and humanized mice, the role of human CD1c+ and CD141+ DCs in determining the type of CD8+ T cell immunity to live-attenuated influenza virus (LAIV) vaccine. We found that both lung DC subsets acquired influenza antigens in vivo and expanded specific cytotoxic CD8+ T cells in vitro. However, lung-tissue-resident CD1c+ DCs but not ...
  14. Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses BioProject

    ID: PRJNA380875

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: erature-reported marker profiles. This revealed a CD141+ DC subets, a CD1c+ DC subset, and a macrophage subset that clustered separately and was found to be enriched in the lesion as compared to other macrophage subsets. Overall design: Using singlet, CD45+ DAPI- CD3- CD19- gating, over 1100 cells from a human stage IA lung adenocarcinoma lesion and over 700 cells from the non-involved lung were sorted into individual wells of a 384-well plate, then processed by MARS-Seq....
  15. Transcriptome profiles of mouse and human monocyte and dendritic cell subsets (mouse data) ArrayExpress

    ID: E-GEOD-35458

    Description: . Although recent evidence points to human blood CD141+ DCs as the functional equivalent of CD8+ DC, the precise identity of the human migratory cross-presenting DC has remained elusive. We performed phenotypic and functional analyses to interrogate the DC compartment of human non-lymphoid tissues and identified three distinct subsets: i) CD141high DCs, ii) CD1c DCs and iii) CD14+ DCs. Only CD141high DCs were capable of cross-presenting soluble antigen. Comparative transcriptome analysis of steady state monocyte and DC subsets between mouse ...

  16. Gene array analysis of human adult lung antigen presenting cells. BioProject

    ID: PRJNA344911

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nocytes (CD14+ cells), classical dendritic cells (CD141+DC and CD1c+ DC) and pDC. Upon stimulation, APC migrate from peripheral organs to lymph nodes, where they drive T cell specific lineage fate, that is towards immune activation or suppression. APC in human tissues...
  17. Gene array analysis of human adult skin and spleen antigen presenting cells. BioProject

    ID: PRJNA338144

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: nocytes (CD14+ cells), classical dendritic cells (CD141+DC and CD1c+ DC) and pDC. Upon stimulation, APC migrate from peripheral organs to lymph nodes, where they drive T cell specific lineage fate, that is towards immune activation or suppression. APC in human tissues ...
  18. TRBM_BOVIN UniProt:Swiss-Prot

    ID: P06579

    Description: Thrombomodulin Extracellular Helical Cytoplasmic EGF-like 1 EGF-like 2 EGF-like 3; calcium-binding EGF-like 4 EGF-like 5 EGF-like 6...

  19. TRBM_CANLF UniProt:Swiss-Prot

    ID: Q5W7P8

    Description: Thrombomodulin Extracellular Helical Cytoplasmic C-type lectin EGF-like 1 EGF-like 2 EGF-like 3; calcium-binding EGF-like 4 EGF-lik...

  20. Transcriptome profiles of mouse and human monocyte and dendritic cell subsets (human data) BioProject

    ID: PRJNA155831

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: . Although recent evidence points to human blood CD141+ DCs as the functional equivalent of CD8+ DC, the precise identity of the human migratory cross-presenting DC has remained elusive. We performed phenotypic and functional analyses to interrogate the DC compartment of human non-lymphoid tissues and identified three distinct subsets: i) CD141high DCs, ii) CD1c DCs and iii) CD14+ DCs. Only CD141high DCs were capable of cross-presenting soluble antigen. Comparative transcriptome analysis of steady state monocyte and DC subsets between mouse ...

Displaying 20 of 78 results for "THBD"