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Displaying 20 of 33 results for "TGM3"
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  1. freshwater sediment metagenome : TGE sediments BioProject

    ID: PRJNA320998

    Keywords: raw sequence reads

    Access Type: download

  2. Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme PDB

    ID: PDB:1NUF

    Description: Protein-glutamine glutamyltransferase E (E.C.2.3.2.13)

  3. Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (2 calciums, 1 Mg, inactive form) PDB

    ID: PDB:1NUG

    Description: Protein-glutamine glutamyltransferase E (E.C.2.3.2.13)

  4. Role of Calcium Ions in the Activation and Activity of the Transglutaminase 3 Enzyme (3 calciums, active form) PDB

    ID: PDB:1NUD

    Description: Protein-glutamine glutamyltransferase E (E.C.2.3.2.13)

  5. Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change structure for activation PDB

    ID: PDB:1L9M

    Description: Protein-glutamine glutamyltransferase E3 (E.C.2.3.2.13)

  6. Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions change structure for activation PDB

    ID: PDB:1L9N

    Description: Protein-glutamine glutamyltransferase E3 (E.C.2.3.2.13)

  7. Thermodesulfovibrio aggregans strain:TGE-P1 : Thermodesulfovibrio aggregans genome sequencing BioProject

    ID: PRJDB4394

    Keywords: Genome sequencing and assembly

    Access Type: download

    dataset.description: Genome sequencing of type strain (TGE-P1, JCM 13213, DSM 17283) of Thermodesulfovibrio aggregans, isolated from thermophilic sludge granules treating organic wastewa...
  8. laryngo-pharyngeal tumor RNA-seq study for both mRNA and miRNA ArrayExpress

    ID: E-GEOD-67994

    Description: teinases along with SCEL, CRNN, KRT4, SPINK5, and TGM3 among others have significantly altered expression in these tumors. Alongside gene expression, the microRNAs hsa-miR-139, hsa-miR-203 and the hsa-miR-424/503 cluster have aberrant expression in these cancers. Using target genes for these microRNAs, we found the involvement of pathways linked to cell cycle, p53 signaling, and viral carcinogenesis significant ( *P*-values 10-13, 10-9 and 10-7 respectively). Finally, using an ensemble machine-learning tool, we discovered a unique 8-gene signature for this group of cancers that differentiates the group from the other subsites of head and neck. We investigated the role of promoter methylation in one of these genes, WIF1, and found no correlation between DNA methylation and down-regulation of WIF1. We validated our findings of gene expression, 8-gene signature and promoter methylation using q-PCR, data from TCGA and q-MSP respectively. RNA-seq experiments in tumors of larynx and hypopharynx for discovery of gene and miRNA expression Please note that processed data files were not provided since they are available th...

  9. TGM3_BOVIN UniProt:Swiss-Prot

    ID: A6QP57

    Description: Protein-glutamine gamma-glutamyltransferase E 50 kDa ca...

  10. laryngo-pharyngeal tumor RNA-seq study for both mRNA and miRNA BioProject

    ID: PRJNA281942

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: teinases along with SCEL, CRNN, KRT4, SPINK5, and TGM3 among others have significantly altered expression in these tumors. Alongside gene expression, the microRNAs hsa-miR-139, hsa-miR-203 and the hsa-miR-424/503 cluster have aberrant expression in these cancers. Using target genes for these microRNAs, we found the involvement of pathways linked to cell cycle, p53 signaling, and viral carcinogenesis significant ( *P*-values 10-13, 10-9 and 10-7 respectively). Finally, using an ensemble machine-learning tool, we discovered a unique 8-gene signature for this group of cancers that differentiates the group from the other subsites of head and neck. We investigated the role of promoter methylation in one of these genes, WIF1, and found no correlation between DNA methylation and down-regulation of WIF1. We validated our findings of gene expression, 8-gene signature and promoter methylation using q-PCR, data from TCGA and q-MSP respectively. Overall design: RNA-seq experiments in tumors of larynx and hypopharynx for discovery of gene and miRNA expression Please note that processed data files were not provided since they a...
  11. Tgl - a bacterial spore coat transglutaminase - cystamine complex PDB

    ID: PDB:4PA5

    Description: Transglutaminase (E.C.2.3.2.13)

  12. Crystal structure of the GP42 transglutaminase from Phytophthora sojae PDB

    ID: PDB:3TW5

    Description: Transglutaminase elicitor (E.C.2.3.2.13)

  13. Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease BioProject

    ID: PRJNA126507

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. Dimer (II) (4040) Dryad

    DateIssued: 08-05-2015

    Description: Mass spectrometry QExactive RAW data file; tryptic digest of self-crosslinked TG2 (dimer, size exclusion fraction II)

    identifiers.ID: doi:10.5061/dryad.0j2k7/3
  15. Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease ArrayExpress

    ID: E-GEOD-21237

    Description: polyglutamine expansion in the mutant huntingtin protein (mhtt), HD pathogenesis impairs function in the cerebral cortex and in medium spiny neurons of the striatum and involves transcriptional dysregulation of a number of genes. Of these genes, silencing of genes related to mitochondrial fu...

  16. Transcription profiling by array of human sputum samples from patients with exercise-induced bronchoconstriction ArrayExpress

    ID: E-GEOD-13785

    Description: confirmed that two novel mediators trefoil factor 3 (TFF3) and transglutaminase 2 (TGM2) have increased expression in airways cells and secreted product in the airways. In vitro studies indicate that 1) TFF3 induces nitric oxide synthase in airway epithelial cells from asthmatics and 2) TGM2 augments the enzymatic activity of secreted phospholipase A2 (sPLA2) group X, an enzyme recently been implicated in asthma pathogenesis. Since PLA2 serves as the first rate-limiting step leading to eicosanoid generation, these results suggest that TGM2 may be a key initiator of the airway inflammatory cascade in asthma. EIB positive and EIB negative subjects sampled pre- an...

  17. HUMAN FACTOR XIII, MUTANT W279F ZYMOGEN PDB

    ID: PDB:1EX0

    Description: HUMAN COAGULATION FACTOR XIII (E.C. 2.3.2.13)

    datasetDistributions.storedIn: Protein Data Bank
  18. THREE-DIMENSIONAL STRUCTURE OF A TRANSGLUTAMINASE: HUMAN BLOOD COAGULATION FACTOR XIII PDB

    ID: PDB:1GGT

    Description: N FACTOR XIII (A-SUBUNIT ZYMOGEN) (E.C.2.3.2.13) (PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE A CHAIN)...

  19. Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease OmicsDI

    ID: E-GEOD-21237

    Date Released: 06-10-2011

    Description: polyglutamine expansion in the mutant huntingtin protein (mhtt), HD pathogenesis impairs function in the cerebral cortex and in medium spiny neurons of the striatum and involves transcriptional dysregulation of a number of genes. Of these genes, silencing of genes related to mitochondrial fu...

  20. Novel mediators of eicosanoid and epithelial nitric oxide production in asthma BioProject

    ID: PRJNA110615

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: confirmed that two novel mediators trefoil factor 3 (TFF3) and transglutaminase 2 (TGM2) have increased expression in airways cells and secreted product in the airways. In vitro studies indicate that 1) TFF3 induces nitric oxide synthase in airway epithelial cells from asthmatics and 2) TGM2 augments the enzymatic activity of secreted phospholipase A2 (sPLA2) group X, an enzyme recently been implicated in asthma pathogenesis. Since PLA2 serves as the first rate-limiting step leading to eicosanoid generation, these results suggest that TGM2 may be a key initiator of the airway inflammatory cascade in asthma. Overall design: EIB positive and EIB negative subjects...

Displaying 20 of 33 results for "TGM3"