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Displaying 20 of 370 results for "TET2"
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  1. Crystal structure of TET2-5fC complex PDB

    ID: PDB:5D9Y

    Description: Methylcytosine dioxygenase TET2/DNA Complex

  2. Crystal structure of TET2-5hmC complex PDB

    ID: PDB:5DEU

    Description: Methylcytosine dioxygenase TET2/DNA Complex

  3. Crystal structure of TET2-DNA complex PDB

    ID: PDB:4NM6

    Description: Methylcytosine dioxygenase TET2 (E.C.1.14.11.-)

  4. TET2 protects the genome from mutagenicity through interacting with MSH6 BioProject

    ID: PRJNA300263

    Keywords: Epigenomics

    Access Type: download

  5. TET2 mutations in acute myeloid leukemia: Results from a comprehensive genetic and clinical analysis of the AML Study Group (AMLSG) ArrayExpress

    ID: E-GEOD-32246

    Description: Purpose: The tet oncogene family member 2 (TET2) gene was recently identified mutated in myeloid disorders...

  6. Mus musculus : Concurrent depletion of Ezh2 and Tet2 propagates epigenomic alterations and accelerates development of myelodysplasia in mice BioProject

    ID: PRJDB1805

    Keywords: Other

    Access Type: download

  7. TET2 mutations in acute myeloid leukemia: Results from a comprehensive genetic and clinical analysis of the AML Study Group (AMLSG) BioProject

    ID: PRJNA147189

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. OGT, H2B S112GlcNAc, TET2 ChIP-seq results BioProject

    ID: PRJNA178017

    Keywords: Epigenomics

    Access Type: download

  9. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma BioProject

    ID: PRJNA167460

    Keywords: Epigenomics

    Access Type: download

    dataset.description: cytosine (5-hmC) by the Ten-Eleven Translocation (TET) family of DNA hydroxylases. Here we report that "loss of 5-hmC" is an epigenetic hallmark of melanoma with diagonostic and prognostic implications. Genome-wide mapping of 5-hmC in nevi and melanomas for the first time revealed loss of 5-hmC landscape in the melanoma epigenome. Downregulation of Isocitr...
  10. Tet2-mediated DNA demethylation controls T cell cytokine expression [array] BioProject

    ID: PRJNA210960

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Expression data from LPS/IFNgamma-treated Tet2-/- and Tet2+/+ mouse macrophages. BioProject

    ID: PRJNA321440

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Acetylation enhances TET2 function in protecting against abnormal DNA methylation during oxidative stress [A2780 TET2 KO - methylation] BioProject

    ID: PRJNA326928

    Keywords: Epigenomics

    Access Type: download

  13. Expression data from Tet2-/- and Tet2+/+ mouse macrophages without any stimuli. BioProject

    ID: PRJNA353395

    Keywords: Transcriptome or Gene expression

    Access Type: download

  14. 5-hydroxymethylcytosine marks promoters in colon that resist hypermethylation in cancer [Methylation450 Array] BioProject

    ID: PRJNA267708

    Keywords: Epigenomics

    Access Type: download

    dataset.description: nd cancer cells express Ten-Eleven Translocation (TET) transcripts at levels similar to normal tissues. Genome-wide analyses show that promoters marked by 5-hmC in normal tissue, and those identified as TET2 targets in colorectal cancer cells, are resistant to methylation gain in cancer. In vitro studies of TET2 in cancer cells confirm that these promoters are resistant to methylation gain independently of sustained TET2 expression. We also find that a considerable number of the meth...
  15. Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA PDB

    ID: PDB:4LT5

    Description: Naegleria Tet-like dioxygenase

  16. ChIP-seq analysis of AF9 and TET2 enrichment in day 12 neural cells BioProject

    ID: PRJNA282457

    Keywords: Epigenomics

    Access Type: download

  17. Loss of 5-hydroxymethylcytosine is an epigenetic hallmark of melanoma ArrayExpress

    ID: E-GEOD-38231

    Description: cytosine (5-hmC) by the Ten-Eleven Translocation (TET) family of DNA hydroxylases. Here we report that "loss of 5-hmC" is an epigenetic hallmark of melanoma with diagonostic and prognostic implications. Genome-wide mapping of 5-hmC in nevi and melanomas for the first time revealed loss of 5-hmC landscape in the melanoma epigenome. Downregulation of Isocitr...

  18. PRDM14 drives OCT3/4 recruitment via active demethylation in the transition from primed to naïve pluripotency BioProject

    ID: PRJNA311046

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: s was impaired by the loss of Kruppel-like factor 2 (Klf2) and ten-eleven translocation (TET) proteins. Furthermore, PRDM14 recruited OCT3/4 to the enhancer regions of naïve pluripotency genes via TET-base excision-repair-mediated demethylation. Our results provide evidence that PRDM14 establishes a transcriptional network for naïve pluripotency via active DNA demethylation. Overall design: To investigate the function of TET1/TET2 in the transition form primed to naïve pluripotency, we exploited microarray analysis using total mRNA derived from Scramble, Scramble + PRDM14, Tet1/Tet2 KD, Tet1/Tet2 KD + PRDM14 mouse ESCs and EpiLCs....
  19. OGT, H2B S112GlcNAc, TET2 ChIP-seq results ArrayExpress

    ID: E-GEOD-41720

    Description: TET2 directly interacts with OGT, which is important for the chromatin association of OGT in vivo. Although this specific interacti...

  20. Effects of miRNA-mediated TET2 in prostate cancer BioProject

    ID: PRJNA275742

    Keywords: Transcriptome or Gene expression

    Access Type: download


Displaying 20 of 370 results for "TET2"