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Displaying 14 of 14 results for "TCF7L1"
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  1. HCT116 TCF7L1 knockdown Microarray BioProject

    ID: PRJNA357593

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Genome-wide maps of TCF7L1 binding during early adipogenesis BioProject

    ID: PRJNA145073

    Keywords: Epigenomics

    Access Type: download

  3. Genome-wide maps of TCF7L1 binding during early adipogenesis ArrayExpress

    ID: E-GEOD-31867

    Description: we show through genome-wide binding studies that transcription factor 7-like 1 (TCF7L1) r...

  4. Genome-wide maps of TCF7L1 binding during early adipogenesis OmicsDI

    ID: E-GEOD-31867

    Date Released: 04-03-2013

    Description: we show through genome-wide binding studies that transcription factor 7-like 1 (TCF7L1) r...

  5. Circulating miRNA Associated with Posttraumatic Stress Disorder in a Cohort of Military Combat Veterans BioProject

    ID: PRJNA347370

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: owth cones. The PTSD associated miRNAs related to transcription factors, including Transcription factor 7 (T-cell specific, HMG-box), Transcription factor 7 like 1, and Transcription factor 7 like 2. Conclusions: PTSD is associated with miRNAs that regulate biological functions that include neuronal activities, suggesting that they play a role in PTSD symptomatology. Overall design: miRNA profiling of 24 human blood samples at two time points to study PTSD...
  6. Wnt and Tcf3-mediated regulation of gene expression in mouse embryonic stem cells ArrayExpress

    ID: E-GEOD-27455

    Description: The observation that Tcf3 (MGI name: Tcf7l1) bound the same genes as core stem cell transcription factors, Oct4 (MGI name:Pou5f1),...

  7. DCT1A_XENLA UniProt:Swiss-Prot

    ID: Q8JJ48

    Description: Dapper 1-A Interaction with tcf7l1-A PDZ-binding Abrogates binding to dvl2

  8. Wnt and Tcf3-mediated regulation of gene expression in mouse embryonic stem cells BioProject

    ID: PRJNA138473

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: The observation that Tcf3 (MGI name: Tcf7l1) bound the same genes as core stem cell transcription factors, Oct4 (MGI name:Pou5f1),...
  9. Control of breast cancer growth and initiation by the stem cell-associated transcription factor TCF3 ArrayExpress

    ID: E-GEOD-38893

    Description: Regulatory factors controlling stem cell identity and self-renewal are often active in aggressive cancers and are thought to promote their growth and progression. TCF3...

  10. Wnt and Tcf3-mediated regulation of gene expression in mouse embryonic stem cells OmicsDI

    ID: E-GEOD-27455

    Date Released: 05-03-2014

    Description: The observation that Tcf3 (MGI name: Tcf7l1) bound the same genes as core stem cell transcription factors, Oct4 (MGI name:Pou5f1),...

  11. Control of breast cancer growth and initiation by the stem cell-associated transcription factor TCF3 BioProject

    ID: PRJNA169317

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Control of breast cancer growth and initiation by the stem cell-associated transcription factor TCF3 OmicsDI

    ID: E-GEOD-38893

    Date Released: 10-29-2012

    Description: Regulatory factors controlling stem cell identity and self-renewal are often active in aggressive cancers and are thought to promote their growth and progression. TCF3...

  13. Smoking-induced Wnt pathway downregulation ArrayExpress

    ID: E-GEOD-19407

    Description: ay downstream targets β-catenin (p<0.05) and the transcription factor 7-like 1 were down-regulated in healthy smokers, and smokers with COPD, as were a number of Wnt target genes, including VEGFA, CCND1, MMP7, CLDN1, SOX9, RHOU (all p<0.05 compared to healthy nonsmokers). As a mechanism to explain this broad, smoking-induced suppression of the Wnt pathway, we assessed expression of the DKK and SFRP families, extracellular regulators that suppress the Wnt pathway. Among these, secreted frizzled-related protein 2 (SFRP2), was up-regulated 4.3-fold (p<0.0001) in healthy smokers and 4.9-fold (p<0.0001) in COPD smokers, an observation confirmed by TaqMan Real-time PCR. AT the protein levels, Western analysis demonstrated SFRP2 up-regulation, and immunohistochemistry demonstrated that the smoking-induced SFRP2 upregulation occurred in differentiated ciliated cells. Finally, cigarette smoke extract mediated up-regulation of SFRP2 and downregulation of Wnt target genes in airway epithelial cells in vitro. These observations ...

  14. Smoking-induced Wnt pathway downregulation BioProject

    ID: PRJNA121779

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ay downstream targets β-catenin (p<0.05) and the transcription factor 7-like 1 were down-regulated in healthy smokers, and smokers with COPD, as were a number of Wnt target genes, including VEGFA, CCND1, MMP7, CLDN1, SOX9, RHOU (all p<0.05 compared to healthy nonsmokers). As a mechanism to explain this broad, smoking-induced suppression of the Wnt pathway, we assessed expression of the DKK and SFRP families, extracellular regulators that suppress the Wnt pathway. Among these, secreted frizzled-related protein 2 (SFRP2), was up-regulated 4.3-fold (p<0.0001) in healthy smokers and 4.9-fold (p<0.0001) in COPD smokers, an observation confirmed by TaqMan Real-time PCR. AT the protein levels, Western analysis demonstrated SFRP2 up-regulation, and immunohistochemistry demonstrated that the smoking-induced SFRP2 upregulation occurred in differentiated ciliated cells. Finally, cigarette smoke extract mediated up-regulation of SFRP2 and downregulation of Wnt target genes in airway epithelial cells in vitro. These observations ...

Displaying 14 of 14 results for "TCF7L1"