TAF7L | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 19 of 19 results for "TAF7L"
i
  1. Taf7l cooperates with Trf2 to regulate spermiogenesis BioProject

    ID: PRJNA219062

    Keywords: Other

    Access Type: download

  2. Expression data from wild type and Taf7l mutant testes BioProject

    ID: PRJNA96071

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Taf7l cooperates with Trf2 to regulate spermiogenesis OmicsDI

    ID: E-GEOD-50807

    Date Released: 10-24-2013

    Description: Taf7l (a paralogue of Taf7) and Trf2 (a TBP-related protein) are components of the core promoter complex required for gene/tissue-s...

  4. Taf7l cooperates with Trf2 to regulate spermiogenesis ArrayExpress

    ID: E-GEOD-50807

    Description: Taf7l (a paralogue of Taf7) and Trf2 (a TBP-related protein) are components of the core promoter complex required for gene/tissue-s...

  5. Taf7l Modulates Brown Adipose Tissue Formation BioProject

    ID: PRJNA241016

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Taf7l Modulates Brown Adipose Tissue Formation ArrayExpress

    ID: E-GEOD-55797

    Description: at the TATA-binding protein Associated Factor 7L (Taf7l) is an important regulator of white adipose tissue (WAT) differentiation. Here, we show that Taf7l also serves as a molecular switch between brown fat and muscle lineages in vivo and in vitro. In adipose tissue, Taf7l containing TFIID complexes associate with PPAR´ü...

  7. Dual Functions of TAF7L in Adipocyte Differentiation OmicsDI

    ID: E-GEOD-41937

    Date Released: 05-03-2014

    Description: ue remains poorly understood. Here we report that TAF7L, a paralogue of TFIID subunit TAF7, is enriched in adipocytes and mouse white fat tissue (WAT). Depletion of TAF7L reduced adipocyte-specific gene expression and compromised adipocyte differentiation as well as WA...

  8. Dual Functions of TAF7L in Adipocyte Differentiation BioProject

    ID: PRJNA178771

    Keywords: Other

    Access Type: download

  9. Dual Functions of TAF7L in Adipocyte Differentiation ArrayExpress

    ID: E-GEOD-41937

    Description: ue remains poorly understood. Here we report that TAF7L, a paralogue of TFIID subunit TAF7, is enriched in adipocytes and mouse white fat tissue (WAT). Depletion of TAF7L reduced adipocyte-specific gene expression and compromised adipocyte differentiation as well as WA...

  10. Transcription profiling of mouse wild type and Taf7l mutant testes OmicsDI

    ID: E-GEOD-5510

    Date Released: 03-27-2012

    Description: f most protein-coding genes by RNA polymerase II. TAF7L is an X-linked germ cell-specific paralogue of TAF7, which is a generally expressed component of TFIID. Here we report the generation of Taf7l mutant mice by homologous recom...

  11. Taf7l Modulates Brown Adipose Tissue Formation OmicsDI

    ID: E-GEOD-55797

    Date Released: 09-08-2014

    Description: at the TATA-binding protein Associated Factor 7L (Taf7l) is an important regulator of white adipose tissue (WAT) differentiation. Here, we show that Taf7l also serves as a molecular switch between brown fat and muscle lineages in vivo and in vitro. In adipose tissue, Taf7l containing TFIID complexes associate with PPAR´ü...

  12. Transcription profiling of mouse wild type and Taf7l mutant testes ArrayExpress

    ID: E-GEOD-5510

    Description: f most protein-coding genes by RNA polymerase II. TAF7L is an X-linked germ cell-specific paralogue of TAF7, which is a generally expressed component of TFIID. Here we report the generation of Taf7l mutant mice by homologous recom...

  13. High-throughput sequencing of mouse liver transcriptome in Clock mutant animals ArrayExpress

    ID: E-GEOD-41082

    Description: Circadian profile of polyA RNA by RNA-Seq, collected from ClockΔ19 mouse liver at CT22, CT28, CT34, CT40. RNA from three livers pooled per time point...

  14. High-throughput sequencing of mouse liver transcriptome in Clock mutant animals BioProject

    ID: PRJNA175697

    Keywords: Transcriptome or Gene expression

    Access Type: download

  15. Taf7l deficiency effect on the testis GEO

    ID: geo.datasets:GDS2857

    Description: Analysis of testes of animals lacking Taf7l. TAF7L is an X-linked germ cell-specific paralog of TAF7, which is a generally expressed component of TFII...

    Types: Expression profiling by array

    Instrument: GPL1261

  16. Gene expression signature of HPV in head and neck squamous cell carcinoma GEMMA

    ID: 2638

    Keywords: functional genomics

    Description: 16INK4A, p18 and CDK2) and transcription factors (TAF7L, RFC4, RPA2 and TFDP2). The microarray data were also investigated using DIGMap to map genes by chromosomal location. A large number of genes on chromosome 3q24-qter was found to be overrepresented in HPV(+) tumors. Conclusion: The gene expression profile associated with HPV reflects alterations in cell cycle and proliferation signals. Further investigation of differentially expressed genes may reveal the unique pathways in HPV(+) tumors that may explain the different natural history and biological properties of these tumors. These properties may be exploited as a target of novel therapeutic agents in HNSCC treatment. Last Updated (by provider): Jan 12 2011 Contributers: Christine H Chung Yajun Yi Anthony J Cmelak Kim Ely Jesse Carter Yu Shyr Amy Evjen Barbara M Murphy Brian B Burkey Robbert Slebos Wendell G Yarbrough Xueqiong Zhang Shawn Levy James L Netterville Includes GDS1667. Update date: Sep 01 2006. Dataset description GDS1667: Analysis of 8 head and neck squamous cell carcinoma (HNSCC) tumors positive for human papilloma virus (HPV). 28 HNSCC HPV negative tumors examined. Between 15% and 35% of HNSCCs harbor HPV DNA. Results provide insight into the effect of HPV infection in HNSCC.....

  17. Transcription profiling of human head and neck squamous cell carcinomas that are positive or negative for Human Papilloma Virus ArrayExpress

    ID: E-GEOD-3292

    Description: 16INK4A, p18 and CDK2) and transcription factors (TAF7L, RFC4, RPA2 and TFDP2). The microarray data were also investigated using DIGMap to map genes by chromosomal location. A large number of genes on chromosome 3q24-qter was found to be overrepresented in HPV(+) tumors. Conclusion: The gene expression profile associated with HPV reflects alterations in cell cycle and proliferation signals. Further investigation of differentially expressed genes may reveal the unique pathways in HPV(+) tumors that may explain the different natural history and biological properties of these tumors. These properties may be exploited as a target of novel therapeutic agents in HNSCC treatment. Experiment Overall Design: Patient selection and specimen collection. Thirty-six freshly frozen tumor samples were prospectively collected from patients undergoing surgery or biopsy for HNSCC at the University of North Carolina (UNC) at Chapel Hill (21 patients) and Vanderbilt University (15 patients). All tissues were snap-frozen in liquid nitrogen within 30 minutes of surgical resection or biopsy, and kept at -80oC until further processing. All patients consented to participation in this study under protocols approved by IRB at the two institutions. Experiment Overall Design: HPV detection and DNA sequencing. Tumor DNAs were tested for the presence of HPV DNA using a previously established PCR-based method [11]. This method employs degenerate PCR primers (MY09 and MY11, WD72/76 and WD66/67/154) that are designed to represent highly conserved HPV L1 ...

  18. Transcription profiling of human head and neck squamous cell carcinomas that are positive or negative for Human Papilloma Virus OmicsDI

    ID: E-GEOD-3292

    Date Released: 05-04-2014

    Description: 16INK4A, p18 and CDK2) and transcription factors (TAF7L, RFC4, RPA2 and TFDP2). The microarray data were also investigated using DIGMap to map genes by chromosomal location. A large number of genes on chromosome 3q24-qter was found to be overrepresented in HPV(+) tumors. Conclusion: The gene expression profile associated with HPV reflects alterations in cell cycle and proliferation signals. Further investigation of differentially expressed genes may reveal the unique pathways in HPV(+) tumors that may explain the different natural history and biological properties of these tumors. These properties may be exploited as a target of novel therapeutic agents in HNSCC treatment. Experiment Overall Design: Patient selection and specimen collection. Thirty-six freshly frozen tumor samples were prospectively collected from patients undergoing surgery or biopsy for HNSCC at the University of North Carolina (UNC) at Chapel Hill (21 patients) and Vanderbilt University (15 patients). All tissues were snap-frozen in liquid nitrogen within 30 minutes of surgical resection or biopsy, and kept at -80oC until further processing. All patients consented to participation in this study under protocols approved by IRB at the two institutions. Experiment Overall Design: HPV detection and DNA sequencing. Tumor DNAs were tested for the presence of HPV DNA using a previously established PCR-based method [11]. This method employs degenerate PCR primers (MY09 and MY11, WD72/76 and WD66/67/154) that are designed to represent highly conserved HPV L1 ...

  19. Gene expression signature of HPV in head and neck squamous cell carcinoma BioProject

    ID: PRJNA92797

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: 16INK4A, p18 and CDK2) and transcription factors (TAF7L, RFC4, RPA2 and TFDP2). The microarray data were also investigated using DIGMap to map genes by chromosomal location. A large number of genes on chromosome 3q24-qter was found to be overrepresented in HPV(+) tumors. Conclusion: The gene expression profile associated with HPV reflects alterations in cell cycle and proliferation signals. Further investigation of differentially expressed genes may reveal the unique pathways in HPV(+) tumors that may explain the different natural history and biological properties of these tumors. These properties may be exploited as a target of novel therapeutic agents in HNSCC treatment. Keywords: HPV, HNSCC, head and neck cancer, human, human papilloma virus Overall design: Patient selection and specimen collection. Thirty-six freshly frozen tumor samples were prospectively collected from patients undergoing surgery or biopsy for HNSCC at the University of North Carolina (UNC) at Chapel Hill (21 patients) and Vanderbilt University (15 patients). All tissues were snap-frozen in liquid nitrogen within 30 minutes of surgical resection or biopsy, and kept at -80oC until further processing. All patients consented to participation in this study under protocols approved by IRB at the two institutions. HPV detection and DNA sequencing. Tumor DNAs were tested for the presence of HPV DNA using a previously established PCR-based method [11]. This method employs degenerate PCR primers (MY09 and MY11, WD72/76 and WD66/67/154) that are designed to r...

Displaying 19 of 19 results for "TAF7L"