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Displaying 9 of 9 results for "SYNGR3"
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  1. SNG3_BOVIN UniProt:Swiss-Prot

    ID: A2VE58

    Description: Synaptogyrin-3 Helical Helical Helical Helical MARVEL N-acetylmethionine

  2. Transcription profiling by array of human chromophobe renal cell carcinoma and oncocytoma samples ArrayExpress

    ID: E-GEOD-19982

    Description: with 94% accuracy. Parafibromin, aquaporin 6, and synaptogyrin 3 were novel immunohistochemical markers effectively discriminating the two pathologic entities. Conclusion : Gene expression profiles and pathway analysis effectively distinguish chRCC from oncocytoma. We have generated a novel transcript predictor that is able to discriminate between the two entities accurately, and which has been validated both in an internal and an independent data-set, implying generalizability. We have identified a series of immunohistochemical markers that are clinically useful in discriminating chRCC and oncocytoma. 30 mRNA profiling samples (15 chromophobe RCC, 15 oncocytoma)...

  3. Gene expression discriminates chromophobe renal cell carcinoma and oncocytoma BioProject

    ID: PRJNA120139

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: with 94% accuracy. Parafibromin, aquaporin 6, and synaptogyrin 3 were novel immunohistochemical markers effectively discriminating the two pathologic entities. Conclusion : Gene expression profiles and pathway analysis effectively distinguish chRCC from oncocytoma. We have generated a novel transcript predictor that is able to discriminate between the two entities accurately, and which has been validated both in an internal and an independent data-set, implying generalizability. We have identified a series of immunohistochemical markers that are clinically useful in discriminating chRCC and oncocytoma. Overall design: 30 mRNA profiling samples (15 chromophobe RCC, 15 oncocytoma)...
  4. Gene expression discriminates chromophobe renal cell carcinoma and oncocytoma GEMMA

    ID: 2322

    Keywords: functional genomics

    Description: with 94% accuracy. Parafibromin, aquaporin 6, and synaptogyrin 3 were novel immunohistochemical markers effectively discriminating the two pathologic entities. Conclusion : Gene expression profiles and pathway analysis effectively distinguish chRCC from oncocytoma. We have generated a novel transcript predictor that is able to discriminate between the two entities accurately, and which has been validated both in an internal and an independent data-set, implying generalizability. We have identified a series of immunohistochemical markers that are clinically useful in discriminating chRCC and oncocytoma. Last Updated (by provider): Dec 15 2010 Contributers: Bin T Teh Min H Tan...

  5. Transcription profiling by array of human chromophobe renal cell carcinoma and oncocytoma samples OmicsDI

    ID: E-GEOD-19982

    Date Released: 05-02-2014

    Description: with 94% accuracy. Parafibromin, aquaporin 6, and synaptogyrin 3 were novel immunohistochemical markers effectively discriminating the two pathologic entities. Conclusion : Gene expression profiles and pathway analysis effectively distinguish chRCC from oncocytoma. We have generated a novel transcript predictor that is able to discriminate between the two entities accurately, and which has been validated both in an internal and an independent data-set, implying generalizability. We have identified a series of immunohistochemical markers that are clinically useful in discriminating chRCC and oncocytoma. 30 mRNA profiling samples (15 chromophobe RCC, 15 oncocytoma)...

  6. Transcription profiling of human brain samples from HIV infected individuals with HIV encephalitis vs controls ArrayExpress

    ID: E-GEOD-3489

    Description: naptic plasticity and transmission (ion channels, synaptogyrin, synapsin II), cell cycle (p35, p39, CDC-L2, CDC42, PAK1) and signaling molecules (PI3K, Ras-Raf-MEK1), transcription factors and cytoskeletal components (MAP-1B, MAP-2, tubulin, adducin-2). Upregulated genes included those involved in neuroimmune (IgG, MHC, ?2microglobulin) and anti-viral responses (interferon-inducible molecules), transcription (STAT1, OLIG2, Pax-6) and signaling modulation (MEK3, EphB1) of the cytoskeleton (myosin, aduccin-3, radixin, dystrobrevin). Taken together, this study suggests that HIV proteins released from infected macrophages might not only induce a neuroinflammatory response, but also may promote neurodegeneration by interfering with neuronal transcription of genes involved in regulating signaling and cytoskeletal molecules important in maintaining synapto-dendritic functioning and integrity. RNA was obtained from brain slabs that are rapidly frozen after removal and stored at ?80 °C for subsequent molecular and biochemical analysis. ...

  7. Transcription profiling of human brain samples from HIV infected individuals with HIV encephalitis vs controls OmicsDI

    ID: E-GEOD-3489

    Date Released: 03-27-2012

    Description: naptic plasticity and transmission (ion channels, synaptogyrin, synapsin II), cell cycle (p35, p39, CDC-L2, CDC42, PAK1) and signaling molecules (PI3K, Ras-Raf-MEK1), transcription factors and cytoskeletal components (MAP-1B, MAP-2, tubulin, adducin-2). Upregulated genes included those involved in neuroimmune (IgG, MHC, ?2microglobulin) and anti-viral responses (interferon-inducible molecules), transcription (STAT1, OLIG2, Pax-6) and signaling modulation (MEK3, EphB1) of the cytoskeleton (myosin, aduccin-3, radixin, dystrobrevin). Taken together, this study suggests that HIV proteins released from infected macrophages might not only induce a neuroinflammatory response, but also may promote neurodegeneration by interfering with neuronal transcription of genes involved in regulating signaling and cytoskeletal molecules important in maintaining synapto-dendritic functioning and integrity. RNA was obtained from brain slabs that are rapidly frozen after removal and stored at ?80 °C for subsequent molecular and biochemical analysis. ...

  8. Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis GEMMA

    ID: 18

    Keywords: functional genomics

    Description: naptic plasticity and transmission (ion channels, synaptogyrin, synapsin II), cell cycle (p35, p39, CDC-L2, CDC42, PAK1) and signaling molecules (PI3K, Ras-Raf-MEK1), transcription factors and cytoskeletal components (MAP-1B, MAP-2, tubulin, adducin-2). Upregulated genes included those involved in neuroimmune (IgG, MHC, ?2microglobulin) and anti-viral responses (interferon-inducible molecules), transcription (STAT1, OLIG2, Pax-6) and signaling modulation (MEK3, EphB1) of the cytoskeleton (myosin, aduccin-3, radixin, dystrobrevin). Taken together, this study suggests that HIV proteins released from infected macrophages might not only induce a neuroinflammatory response, but also may promote neurodegeneration by interfering with neuronal transcription of genes involved in regulating signaling and cytoskeletal molecules important in maintaining synapto-dendritic functioning and integrity.. Date GSE3489 Last Updated: Mar 07 2006 Contributers: Eleanor S Roberts Dianne Langford Anthony Adame Edward Rockenstein Leslie Crews Howard S F...

  9. Patterns of gene dysregulation in the frontal cortex of patients with HIV encephalitis BioProject

    ID: PRJNA93309

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: naptic plasticity and transmission (ion channels, synaptogyrin, synapsin II), cell cycle (p35, p39, CDC-L2, CDC42, PAK1) and signaling molecules (PI3K, Ras-Raf-MEK1), transcription factors and cytoskeletal components (MAP-1B, MAP-2, tubulin, adducin-2). Upregulated genes included those involved in neuroimmune (IgG, MHC, β2microglobulin) and anti-viral responses (interferon-inducible molecules), transcription (STAT1, OLIG2, Pax-6) and signaling modulation (MEK3, EphB1) of the cytoskeleton (myosin, aduccin-3, radixin, dystrobrevin). Taken together, this study suggests that HIV proteins released from infected macrophages might not only induce a neuroinflammatory response, but also may promote neurodegeneration by interfering with neuronal transcription of genes involved in regulating signaling and cytoskeletal molecules important in maintaining synapto-dendritic functioning and integrity. Keywords: HIVE, HIV, AIDS, Microarray, neuroimmunity, neuroinflammatory, neurodegeneration Overall design: RNA was obtained from brain slabs that...

Displaying 9 of 9 results for "SYNGR3"