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Displaying 13 of 13 results for "SVIL"
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  1. Solution Structure of Human Supervillin Headpiece PDB

    ID: PDB:2K6M

    Description: Supervillin

  2. Solution Structure of Human Supervillin Headpiece, Minimized Average PDB

    ID: PDB:2K6N

    Description: Supervillin

  3. The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation [ChIP-Seq] BioProject

    ID: PRJNA251753

    Keywords: Epigenomics

    Access Type: download

    dataset.description: ng H3K9 repressive histone marks. We identify the supervillin protein (SVIL) as a LSD1+8a interacting partner and demonstrate that SVIL protein regulates neuronal maturation by controlling LSD1+8a mediated H3K9 demethylation. Thus, our results show that alternative splicing provides a genius mechanism by which LSD1 isoforms can acquire a dual specificity (H3K9 vs H3K4) and therefore differentially control specific gene expression patterns during brain development. Overall design: Examination of 2 different LSD1 isoforms LSD1 and LSD1+8a, LSD1+8a's cofactor SVIL, H3K9me2 in SH-SY5Y cells infected with control or LSD1+8a shRNA during neuronal maturation induced with BNDF at Day0(B0) and Day3(B3).ChIP-seq datas were generated by de...
  4. SVIL_BOVIN UniProt:Swiss-Prot

    ID: O46385

    Description: Supervillin Gelsolin-like 1 Gelsolin-like 2 Gelsolin-like 3 Gelsolin-like 4 Gelsolin-like 5 HP Interaction with MYLK Interaction wi...

  5. The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation [Affymetrix] ArrayExpress

    ID: E-GEOD-63097

    Description: ng H3K9 repressive histone marks. We identify the supervillin protein (SVIL) as a LSD1+8a interacting partner and demonstrate that SVIL protein regulates neuronal maturation by controlling LSD1+8a mediated H3K9 demethylation. Thus, our results show that alternative splicing provides a genius mechanism by which LSD1 isoforms can acquire a dual specificity (H3K9 vs H3K4) and therefore differentially control specific gene expression patterns during brain development. In order to find some LSD1+8a regulated genes at differentiated SH-SY5Y cell lines, we infected SH-SY5Y with control or LSD1+8a shRNA, then induced differentiation with RA and BDNF, (Retinoic acid (RA) (Sigma) was added at a final concentration of 10 μM the next day after plating. After...

  6. The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation [Affymetrix] OmicsDI

    ID: E-GEOD-63097

    Date Released: 06-13-2015

    Description: ng H3K9 repressive histone marks. We identify the supervillin protein (SVIL) as a LSD1+8a interacting partner and demonstrate that SVIL protein regulates neuronal maturation by controlling LSD1+8a mediated H3K9 demethylation. Thus, our results show that alternative splicing provides a genius mechanism by which LSD1 isoforms can acquire a dual specificity (H3K9 vs H3K4) and therefore differentially control specific gene expression patterns during brain development. In order to find some LSD1+8a regulated genes at differentiated SH-SY5Y cell lines, we infected SH-SY5Y with control or LSD1+8a shRNA, then induced differentiation with RA and BDNF, (Retinoic acid (RA) (Sigma) was added at a final concentration of 10 μM the next day after plating. After...

  7. The LSD1/KDM1A neuro-specific isoform regulates neuronal differentiation through H3K9 demethylation [Affymetrix] BioProject

    ID: PRJNA266613

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ng H3K9 repressive histone marks. We identify the supervillin protein (SVIL) as a LSD1+8a interacting partner and demonstrate that SVIL protein regulates neuronal maturation by controlling LSD1+8a mediated H3K9 demethylation. Thus, our results show that alternative splicing provides a genius mechanism by which LSD1 isoforms can acquire a dual specificity (H3K9 vs H3K4) and therefore differentially control specific gene expression patterns during brain development. Overall design: In order to find some LSD1+8a regulated genes at differentiated SH-SY5Y cell lines, we infected SH-SY5Y with control or LSD1+8a shRNA, then induced differentiation with RA and BDNF, (Retinoic acid (RA) (Sigma) was added at a final concentration of 10 μM the next day afte...
  8. Congenital scolisis may be associated with both of rare mutation and allele-specific methylation BioProject

    ID: PRJNA248908

    Keywords: Epigenomics

    Access Type: download

    dataset.description: ele-specific-methylation between the twins in the SVIL gene which has functions in categories relevant to this disease, which raises the possibility of a novel mechanism promoting CS pathogenesis. Overall design: DNA was extracted from peripheral blood of a monozygotic twin pair that was discordant for CS, with T-P affected with CS and T-H non-affected. Followed by MeDIP-seq and exome-seq....
  9. Trichloroethylene-induced mRNA expression changes in B6C3F1 mouse liver ArrayExpress

    ID: E-GEOD-58819

    Description: changed genes, viz., Jun, Cdkn1a, Rad51b, Uhrf1, Svil and Ihh. Six B6C3F1 male mice were oral administrated with either corn oil or TCE (dissolved in corn oil, 1000mg/kg b.w per day) for 5 days. The expression changes of mRNAs in TCE exposured mouse liver were screened by whole genome microarray expression profiling and were validated by qPCR....

  10. Trichloroethylene-induced mRNA expression changes in B6C3F1 mouse liver OmicsDI

    ID: E-GEOD-58819

    Date Released: 11-28-2014

    Description: changed genes, viz., Jun, Cdkn1a, Rad51b, Uhrf1, Svil and Ihh. Six B6C3F1 male mice were oral administrated with either corn oil or TCE (dissolved in corn oil, 1000mg/kg b.w per day) for 5 days. The expression changes of mRNAs in TCE exposured mouse liver were screened by whole genome microarray expression profiling and were validated by qPCR....

  11. Trichloroethylene-induced mRNA expression changes in B6C3F1 mouse liver BioProject

    ID: PRJNA253683

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: changed genes, viz., Jun, Cdkn1a, Rad51b, Uhrf1, Svil and Ihh. Overall design: Six B6C3F1 male mice were oral administrated with either corn oil or TCE (dissolved in corn oil, 1000mg/kg b.w per day) for 5 days. The expression changes of mRNAs in TCE exposured mouse liver were screened by whole genome microarray expression profiling and were validated by qPCR....
  12. red region of the cytoskeleton-regulatory protein supervillin contains Myosin II- and F-actin-binding sites... Figshare

    ID: doi:10.6084/M9.FIGSHARE.825696

    Release Date: 03-10-2016

    Description:

  13. red region of the cytoskeleton-regulatory protein supervillin contains Myosin II- and F-actin-binding sites... Figshare

    ID: doi:10.6084/M9.FIGSHARE.825696.V1

    Release Date: 03-10-2016

    Description:


Displaying 13 of 13 results for "SVIL"