SUMO4 | bioCADDIE Data Discovery Index
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Displaying 6 of 6 results for "SUMO4"
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  1. SUMO4_PIG UniProt:Swiss-Prot

    ID: A7WLI0

    Description: Small ubiquitin-related modifier 4 Ubiquitin-<

  2. SUMO4_ARATH UniProt:Swiss-Prot

    ID: Q9FKC5

    Description: Putative small ubiquitin-related modifier 4 Ubiquitin-<

  3. COMPLEX STRUCTURE OF OSYCHF1 WITH AMP-PNP PDB

    ID: PDB:5EE3

    Description: Small ubiquitin-related modifier,Obg-like ATPase 1 (E.C.3.6.5.-)

  4. IGR_MITF_STUDY_BBRB ArrayExpress

    ID: E-TABM-1198

    Description: frequency in melanoma + RCC patients (p = 1.3x10-4), melanoma -only patients (p = 7.8 x10-5), and RCC-only patients (p = 0.008). Overall, p.E318K substitution carriers had a higher than fivefold increased risk of developing melanoma, RCC or both cancers (odds-ratio = 5.55, 95% confidence interval = 2.59 to 12.91). Codon 318 falls in the second MITF-conserved, small-ubiquitin like modifier (SUMO)-1 consensus binding site (YKXE) and the p.E318K substitution severely impairs SUMOylation of MITF. MITF p.E318K binds more efficiently to the HIF1A promoter and increases its activation compared to the wild type MITF. In RCC cell line, transcriptomic approach identifies a MITF p.E318K signature related to cell growth, proliferation and inflammation. MITF p.E318K is more p...

  5. IGR_MITF_STUDY_BBRB OmicsDI

    ID: E-TABM-1198

    Date Released: 05-02-2014

    Description: frequency in melanoma + RCC patients (p = 1.3x10-4), melanoma -only patients (p = 7.8 x10-5), and RCC-only patients (p = 0.008). Overall, p.E318K substitution carriers had a higher than fivefold increased risk of developing melanoma, RCC or both cancers (odds-ratio = 5.55, 95% confidence interval = 2.59 to 12.91). Codon 318 falls in the second MITF-conserved, small-ubiquitin like modifier (SUMO)-1 consensus binding site (YKXE) and the p.E318K substitution severely impairs SUMOylation of MITF. MITF p.E318K binds more efficiently to the HIF1A promoter and increases its activation compared to the wild type MITF. In RCC cell line, transcriptomic approach identifies a MITF p.E318K signature related to cell growth, proliferation and inflammation. MITF p.E318K is more p...

  6. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells OmicsDI

    ID: PXD000716

    Date Released: 12-09-2014

    Description: dification involving covalent attachment of SUMO (Small Ubiquitin-like Modifier) polypeptides to specific lysine residues in the target protein. In human cells, there are...


Displaying 6 of 6 results for "SUMO4"