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Displaying 20 of 31 results for "STIM1"
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  1. NMR structure of calcium-loaded STIM1 EF-SAM PDB

    ID: PDB:2K60

    Description: Stromal interaction molecule 1

  2. The Structure of CC1-IH in human STIM1. PDB

    ID: PDB:4O9B

    Description: Stromal interaction molecule 1

  3. Solution Structure of the STIM1 CC1-CC2 homodimer. PDB

    ID: PDB:2MAJ

    Description: Stromal interaction molecule 1

  4. Crystal structure of SOAR domain PDB

    ID: PDB:3TEQ

    Description: Stromal interaction molecule 1

  5. Solution structure of the STIM1 CC1-CC2 homodimer in complex with two Orai1 C-terminal domains. PDB

    ID: PDB:2MAK

    Description: Stromal interaction molecule 1, Calcium release-activated calcium channel ...

  6. Store operated Ca2+ entry (SOCE) controls ameloblast cell function and enamel development BioProject

    ID: PRJNA361476

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ons in the endoplasmic reticulum (ER) Ca2+ sensor stromal interaction molecule 1 (STIM1) result is a number of disease s...
  7. Bone marrow micro-environment mediated drug resistance in Acute promyelocytic leukemia BioProject

    ID: PRJNA296065

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: data on the effect of malignant promyelocyte and stromal interaction on Arsenic trioxide (ATO) induced apoptosis. We undertook a preliminary study to evaluate the role of EM-DR to ATO in APL. In direct co-culture (contact dependent system) of malignant promyelocyte with stromal cells, the stromal cells gave a significant protective effect against ATO at different concentrations used (1
  8. Bone marrow micro-environment mediated drug resistance in Acute promyelocytic leukemia ArrayExpress

    ID: E-GEOD-73157

    Description: data on the effect of malignant promyelocyte and stromal interaction on Arsenic trioxide (ATO) induced apoptosis. We undertook a preliminary study to evaluate the role of EM-DR to ATO in APL. In direct co-culture (contact dependent system) of malignant promyelocyte with stromal cells, the stromal cells gave a significant protective effect against ATO at different concentrations used (1

  9. Epstein Barr virus Nuclear Antigen 3C regulated genes in Lymphoblastoid Cell Lines ArrayExpress

    ID: E-GEOD-24362

    Description: anscription factor for initiating and maintaining human B lymphocyte transformation to lymphoblastoid cell lines (LCLs). To comprehensively identify EBNA3C regulated cell genes in LCLs, oligonucleotide arrays were used to compare RNA abundances in 3 di...

  10. STIM1 controls T cell mediated immune regulation and inflammation in chronic infection BioProject

    ID: PRJNA278467

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Gene expression profile of STIM1 deficiency for cardiac remodeling in response to pressure overload by transverse aortic constriction (TAC) ArrayExpress

    ID: E-GEOD-38733

    Description: STIM1 is a Ca2+ sensor of intracellular Ca2+ stores and essentially activates the Ca2+ entry channels of the plasma membrane.

  12. Gene expression profile of STIM1 deficiency for cardiac remodeling in response to pressure overload by transverse aortic constriction (TAC) BioProject

    ID: PRJNA168507

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. Epstein Barr virus Nuclear Antigen 3C regulated genes in Lymphoblastoid Cell Lines BioProject

    ID: PRJNA132823

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: anscription factor for initiating and maintaining human B lymphocyte transformation to lymphoblastoid cell lines (LCLs). To comprehensively identify EBNA3C regulated cell genes in LCLs, oligonucleotide arrays were used to compare RNA abundances in 3 di...
  14. Systematic mapping of RNA-chromatin interactions in vivo BioProject

    ID: PRJNA357269

    Keywords: Other

    Access Type: download

    dataset.description: d sequencing. Using MARGI, we produced RNA-genome interaction maps for human embryonic stem (ES) cells and HEK cells. MARGI revealed hundreds of chromatin-associated RNAs (caRNA), including previously known XIST, SNHG1, NEAT1, and MALAT1, as well as each caRNA's genomic interaction loci. Using a cross-species experiment, we estimated that approximately 2.2% of MARGI identified interactions are false positives. MARGI data suggested that 80-95% of interactions are proximal, where a caRNA is connected to its nearby genomic regions, 1-2% are distal, and 5-15% are inter-chromosomal. The majority of TSSs are associated with distal or inter-chromosomal caRNAs. ChIP-seq reported H3K27ac and H3K4me3 levels ...
  15. Gene expression profile of STIM1 deficiency for cardiac remodeling in response to pressure overload by transverse aortic constriction (TAC) OmicsDI

    ID: E-GEOD-38733

    Date Released: 07-08-2014

    Description: STIM1 is a Ca2+ sensor of intracellular Ca2+ stores and essentially activates the Ca2+ entry channels of the plasma membrane.

  16. T Cell Receptor-Induced NF-kB Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-Mediated Calcium Entry BioProject

    ID: PRJNA308743

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. T Cell Receptor-Induced NF-kB Signaling and Transcriptional Activation Are Regulated by STIM1- and Orai1-Mediated Calcium Entry ArrayExpress

    ID: E-GEOD-76804

    Description: ely requires the influx of extracellular Ca2+ via STIM1-dependent CRAC/Orai channels. We further show that Ca2+ influx controls phosphorylation of the NF-κB protein p65 on Ser536 and that this post- translational modification controls its nuclear localization and transcriptional activation. Notably our data reveal that this role for Ca2+ is entirely separate from its upstream control of IκBα degradation, thereby identifying a novel Ca2+- dependent distal step in TCR-induced NF-κB activation. Finally, we demonstrate that this control of distal signaling occurs via Ca2+-dependent PKCk-mediated phosphorylation of p65. Thus, we establish the source of Ca2+ requi...

  18. CRCM1_RAT UniProt:Swiss-Prot

    ID: Q5M848

    Description: Calcium release-activated calcium channel protein 1 Cytoplasmic Helical Extracellular Helical Cytoplasmic Helical Extracellular Helical Cytoplasmic

  19. Store-operated Ca2+ entry in follicular T cells controls humoral immune responses and autoimmunity ArrayExpress

    ID: E-GEOD-79039

    Description: f both TFH and TFR cells. Conditional deletion of Stim1 and Stim2 genes in T cells or Treg cells results in spontaneous autoantibody production and humoral autoimmunity. Conversely, antibody-mediated immune responses following viral infection critically depend on SOCE in TFH cells. Mechanistically, STIM1 and STIM2 control early TFR and TFH cell differentiation through NFAT-mediated IRF4, BATF and Bcl-6 expression. SOCE plays a dual role in GC response by controlling TFH and TFR cell function, thus enabling protective B cell responses and preventing humoral autoim...

  20. Store-operated Ca2+ entry in follicular T cells controls humoral immune responses and autoimmunity BioProject

    ID: PRJNA314788

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: f both TFH and TFR cells. Conditional deletion of Stim1 and Stim2 genes in T cells or Treg cells results in spontaneous autoantibody production and humoral autoimmunity. Conversely, antibody-mediated immune responses following viral infection critically depend on SOCE in TFH cells. Mechanistically, STIM1 and STIM2 control early TFR and TFH cell differentiation through NFAT-mediated IRF4, BATF and Bcl-6 expression. SOCE plays a dual role in GC response by controlling TFH and TFR cell function, thus enabling protective B cell responses and preventing humoral autoim...

Displaying 20 of 31 results for "STIM1"