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Displaying 20 of 35 results for "SRRM2"
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  1. A systematic characterization of Cwc21, the yeast ortholog of the human spliceosomal protein SRm300 BioProject

    ID: PRJNA118835

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. BioProject

    ID: PRJNA323919

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. T cell Activation is Regulated by Assembly of an RNA-binding Interactome Centered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP ArrayExpress

    ID: E-GEOD-62923

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  4. tered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [total RNA-array]... ArrayExpress

    ID: E-GEOD-62921

    Description: cific U2AF2 interacting partners (U2AF1, SYNCRIP, SRRM2, ILF2) selectively affects cytokine secretion and expression of activation markers. Furthermore, the expression and/or alternative splicing of transcripts important for immune cell function are also affected by knocking down these U2AF2 interacting proteins. U2AF1 and SYNCRIP knockdowns affect the proteins and transcripts bound to U2AF2, altering the transcriptome. Our work highlights the importance of RNA binding protein complexes in regulating the differential expression and alternative splicing that defines T cell activation. HTA 2.0 microarray results of total from a primary CD4 T cell culture after treatment with siRNAs (Control,...

  5. ofiling by array of budding yeast with or without cwc21 knockout after shift to 37°C from 30°C for 0, 30 and 60 minutes to study the effect of the deletion on pre-mRNA processing... ArrayExpress

    ID: E-MTAB-3240

    Description: he effects of deletion of the gene coding for the cwc21 protein in the budding yeast Saccharomyces cerevisiae. This was performed after shift to 37°C from 30°C at 0, 30 and 60 minutes after shift. The p...

  6. tered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [total RNA-array]... OmicsDI

    ID: E-GEOD-62921

    Date Released: 12-02-2015

    Description: cific U2AF2 interacting partners (U2AF1, SYNCRIP, SRRM2, ILF2) selectively affects cytokine secretion and expression of activation markers. Furthermore, the expression and/or alternative splicing of transcripts important for immune cell function are also affected by knocking down these U2AF2 interacting proteins. U2AF1 and SYNCRIP knockdowns affect the proteins and transcripts bound to U2AF2, altering the transcriptome. Our work highlights the importance of RNA binding protein complexes in regulating the differential expression and alternative splicing that defines T cell activation. HTA 2.0 microarray results of total from a primary CD4 T cell culture after treatment with siRNAs (Control,...

  7. tered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [RIP-seq]... ArrayExpress

    ID: E-GEOD-62919

    Description: cific U2AF2 interacting partners (U2AF1, SYNCRIP, SRRM2, ILF2) selectively affects cytokine secretion and expression of activation markers. Furthermore, the expression and/or alternative splicing of transcripts important for immune cell function are also affected by knocking down these U2AF2 interacting proteins. U2AF1 and SYNCRIP knockdowns affect the proteins and transcripts bound to U2AF2, altering the transcriptome. Our work highlights the importance of RNA binding protein complexes in regulating the differential expression and alternative splicing that defines T cell activation. U2AF2 RIPseq on a primary CD4 T cell culture at rest and 48 hours after anti-CD3/CD28 bead activation...

  8. Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion ArrayExpress

    ID: E-GEOD-82070

    Description: We analysed whole PolyA+ RNA from human osteosarcoma U2OS cells depleted for human Cactin or transfected with a control shRNA. Two independent shRNAs ...

  9. tered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [RNA-seq]... ArrayExpress

    ID: E-GEOD-62920

    Description: cific U2AF2 interacting partners (U2AF1, SYNCRIP, SRRM2, ILF2) selectively affects cytokine secretion and expression of activation markers. Furthermore, the expression and/or alternative splicing of transcripts important for immune cell function are also affected by knocking down these U2AF2 interacting proteins. U2AF1 and SYNCRIP knockdowns affect the proteins and transcripts bound to U2AF2, altering the transcriptome. Our work highlights the importance of RNA binding protein complexes in regulating the differential expression and alternative splicing that defines T cell activation. RNAseq of total RNA from a primary CD4 T cell culture at rest and 48 hours after anti-CD3/CD28 bead activat...

  10. Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) PDB

    ID: PDB:5MQF

    Description: og, Spliceosome-associated protein CWC15 homolog, Serine/arginine repetitive matrix protein 2, Pre-mRNA-splicing factor CWC22 homolog, Intron-binding protein aquarius, Peptidyl-prolyl cis-trans isomerase-like 1, U2 small nuclear ribonucleoprotein A', U2 small nuclear ribonucleoprotein B'', Small nuclear ribonucleoprotein Sm D2, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein G, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein Sm D1, Pept...

  11. tered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [RIP-array]... ArrayExpress

    ID: E-GEOD-62922

    Description: cific U2AF2 interacting partners (U2AF1, SYNCRIP, SRRM2, ILF2) selectively affects cytokine secretion and expression of activation markers. Furthermore, the expression and/or alternative splicing of transcripts important for immune cell function are also affected by knocking down these U2AF2 interacting proteins. U2AF1 and SYNCRIP knockdowns affect the proteins and transcripts bound to U2AF2, altering the transcriptome. Our work highlights the importance of RNA binding protein complexes in regulating the differential expression and alternative splicing that defines T cell activation. HTA 2.0 microarray results of U2AF2 RIP RNA from a primary CD4 T cell culture after treatment with siRNAs (...

  12. Human Cactin interacts with DHX8 and SRRM2 to assure efficient pre-mRNA splicing and sister chromatid cohesion. OmicsDI

    ID: E-GEOD-82070

    Date Released: 06-04-2016

    Description: We analysed whole PolyA+ RNA from human osteosarcoma U2OS cells depleted for human Cactin or transfected with a control shRNA. Two independent shRNAs ...

  13. The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells [to... BioProject

    ID: PRJNA266245

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ture after treatment with siRNAs (Control, U2AF1, SRRM2, SYNCRIP, and ILF2) and 24 hours after anti-CD3/CD28 bead activation Please note that the Series supplementary 'TotalRNA_HTA2_all_siRNA_100414.xslx' file has multiple worksheets containing: 1) Differentially expressed genes in ctrl siRNA vs. U2AF1 siRNA; 2) Differntially spliced genes in ctrl siRNA vs. U2AF1 siRNA; 3) Differentially spliced exons in ctrl siRNA vs. U2AF1 siRNA; 4) Differentially expressed genes in ctrl siRNA vs. SRRM2 siRNA; 5) Differntially spliced genes in ctrl siRNA vs. SRRM2 siRNA; 6) Differentially spliced exons in ctrl siRNA vs. SRRM2 siRNA; 7) Differentially expressed genes in ctrl siRNA vs. SYNCRIP siRNA; 8) Differntially spliced genes in ctrl siRNA vs. SYNCRIP siRNA; 9) Differentially spliced exons in ctrl siRNA vs. SYNCRIP siRNA; 10) Differentially expressed genes in ctrl siRNA vs. ILF2 siRNA; 11) Differntially spliced genes in ctrl siRNA vs. ILF2 siRNA; 12) Differentially spliced exons in ctrl siRNA vs. ILF2 siRNA...
  14. tered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [RNA-seq]... OmicsDI

    ID: E-GEOD-62920

    Date Released: 12-02-2015

    Description: cific U2AF2 interacting partners (U2AF1, SYNCRIP, SRRM2, ILF2) selectively affects cytokine secretion and expression of activation markers. Furthermore, the expression and/or alternative splicing of transcripts important for immune cell function are also affected by knocking down these U2AF2 interacting proteins. U2AF1 and SYNCRIP knockdowns affect the proteins and transcripts bound to U2AF2, altering the transcriptome. Our work highlights the importance of RNA binding protein complexes in regulating the differential expression and alternative splicing that defines T cell activation. RNAseq of total RNA from a primary CD4 T cell culture at rest and 48 hours after anti-CD3/CD28 bead activat...

  15. tered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP [RIP-seq]... OmicsDI

    ID: E-GEOD-62919

    Date Released: 12-02-2015

    Description: cific U2AF2 interacting partners (U2AF1, SYNCRIP, SRRM2, ILF2) selectively affects cytokine secretion and expression of activation markers. Furthermore, the expression and/or alternative splicing of transcripts important for immune cell function are also affected by knocking down these U2AF2 interacting proteins. U2AF1 and SYNCRIP knockdowns affect the proteins and transcripts bound to U2AF2, altering the transcriptome. Our work highlights the importance of RNA binding protein complexes in regulating the differential expression and alternative splicing that defines T cell activation. U2AF2 RIPseq on a primary CD4 T cell culture at rest and 48 hours after anti-CD3/CD28 bead activation...

  16. T cell Activation is Regulated by Assembly of an RNA-binding Interactome Centered on the U2AF Heterodimer that Includes ILF2, SRRM2, and SYNCRIP OmicsDI

    ID: E-GEOD-62923

    Date Released: 12-02-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  17. Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution PDB

    ID: PDB:5GMK

    Description: splicing factor SNU114, Pre-mRNA-splicing factor CWC21, Pre-mRNA-splicing factor PRP46, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor SLT11, Pre-mRNA-splicing factor CWC2, Pre-mRNA-splicing factor CWC15...

  18. Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution PDB

    ID: PDB:5GM6

    Description: 3, Prp2, Cwc22, Cwc24, Cwc27, Cef1, Hsh155, Clf1, Cwc21, Syf1, Hsh49, Syf2, Prp19, Snt309, Prp17, SmB, SmE, SmF, SmG, SmD3, SmD1, SmD2/RNA Complex...

  19. Structure of a spliceosome remodeled for exon ligation PDB

    ID: PDB:5MPS

    Description: A-splicing factor CWC15, Pre-mRNA-splicing factor CWC21, Pre-mRNA-splicing factor CLF1, Pre-mRNA-splicing factor SYF1, Pre-mRNA-splicing factor 18, Pre-mRNA-splicing factor SLU7, Pre-mRNA-processing factor 17, Unknown, Pre-mRNA-splicing factor SYF2, Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, Small nuclear ribonucle...

  20. Structure of a spliceosome remodeled for exon ligation PDB

    ID: PDB:5MQ0

    Description: A-splicing factor CWC15, Pre-mRNA-splicing factor CWC21, Pre-mRNA-splicing factor CLF1, Pre-mRNA-splicing factor SYF1, Pre-mRNA-splicing factor 18, Pre-mRNA-splicing factor SLU7, Pre-mRNA-splicing factor SYF2, Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, Small nuclear ribonucleoprotein G, ...


Displaying 20 of 35 results for "SRRM2"