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Displaying 20 of 25 results for "SPATA8"
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  1. Additional file 8: Table S5. of Functional changes in mRNA expression and alternative pre-mRNA splicing associated with the effe... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3661790_D3

    Release Date: 01-10-2017

    Description: Identification of alternative splicing events with Tophat2 software. (XLSX 1164 kb)

  2. Expression changes in mRNA expression associated with the effects of nutrition on apoptosis and spermatogenesis in the adult testis BioProject

    ID: PRJNA282344

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. mRNA expression and alternative pre-mRNA splicing associated with the effects of nutrition on apoptosis and spermatogenesis in the adult testis... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3661790_D7

    Release Date: 01-10-2017

    Description: in testis from sheep fed a low or high diet (N = 8 for each treatment). Note: Fold change (FC) = CPM of low diet group/CPM of high diet group. CPM (Counts per million) = (mRNAs reads number/total reads number p...

  4. Exposure of Feathead Minnows to Municipal Wastewater Effluent Inhibits the Canonical Wnt Signaling Pathway in the Liver ArrayExpress

    ID: E-GEOD-52693

    Description: increased hepatic vitellogenin, intersex, delayed spermatogenesis and altered immune function. Few studies have examined genome-wide effects associated with municipal effluent exposure in fish to decipher the mechanisms of toxicity. The present objective was to identify hepatic cellular signaling pathways ...

  5. Roles of small RNAs in the effects of nutrition on apoptosis and spermatogenesis in the adult testis BioProject

    ID: PRJNA265167

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Exposure of Feathead Minnows to Municipal Wastewater Effluent Inhibits the Canonical Wnt Signaling Pathway in the Liver BioProject

    ID: PRJNA229819

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: increased hepatic vitellogenin, intersex, delayed spermatogenesis and altered immune function. Few studies have examined genome-wide effects associated with municipal effluent exposure in fish to decipher the mechanisms of toxicity. The present objective was to identify hepatic cellular signaling pathways ...
  7. Promoter targeted bisulfite sequencing reveals DNA methylation profiles associated with low sperm motility in asthenozoospermia BioProject

    ID: PRJNA284240

    Keywords: Epigenomics

    Access Type: download

  8. The acute effects of methoxyacetic acid exposure on testis gene expression GEMMA

    ID: 766

    Keywords: functional genomics

    Description: isms by which 2-methoxyacetic acid (MAA) disrupts spermatogenesis using high density microarrays. Levels of mRNA transcripts were determined in total RNA isolated from testes of MAA-treated (650 mg/kg i.p.) or co...

  9. Exposure of Feathead Minnows to Municipal Wastewater Effluent Inhibits the Canonical Wnt Signaling Pathway in the Liver OmicsDI

    ID: E-GEOD-52693

    Date Released: 09-07-2014

    Description: increased hepatic vitellogenin, intersex, delayed spermatogenesis and altered immune function. Few studies have examined genome-wide effects associated with municipal effluent exposure in fish to decipher the mechanisms of toxicity. The present objective was to identify hepatic cellular signaling pathways ...

  10. The human AlkB homologue 4 interacts with proteins associated with transcription (expression) BioProject

    ID: PRJNA170065

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. Germ cell nuclear factor regulates gametogenesis in developing gonads ArrayExpress

    ID: E-GEOD-57506

    Description: ls correlates with the expression of pluripotency-associated genes, such as Oct4, Sox2, and Nanog, as well as the early meiotic marker gene Stra8. To elucidate the role of Gcnf during mouse germ cell differentiation, we generated an ex vivo Gcnf-knockdown model in combination with a regulated CreLox mutation of Gcnf. Lack of Gcnf impairs normal spermatogenesis and oogenesis in vivo, as well as the derivation of germ cells from embryonic stem cells (ESCs) in vitro. Inactivation of the Gcnf gene in vivo leads to loss of repression of Oct4 expression in both male and female gonads. For RNA isolation, PGCs were sorted by FACS, collected by centrifugation, lyse...

  12. Transcription profiling of cerebellum from Mecp2 mutant mice to identify pathways mis-regulated by MeCP2 deficiency in Rett Syndrome ArrayExpress

    ID: E-SMDB-4087

    Description: and seizures. Most mutations occur de novo during spermatogenesis. Located at Xq28, MECP2 is subject to X inactivation, and affected females are mosaic. Rare hemizygous males suffer from a severe congenital encephalopathy. Methods To identify pathways mis-regulated by MeCP2 deficiency, microarray-based global gene expression studies were carried out on cerebellum of Mecp2 mutant mice. We compared transcript levels in mutant/wildtype male sibs of two different MeCP2-deficient mouse models at 2, 4 and 8 weeks of age. Increased transcript levels were evaluated by real-time quan...

  13. Cerebellar gene expression profiles of mouse models for Rett Syndrome reveal MeCP2 targets ArrayExpress

    ID: E-GEOD-8774

    Description: and seizures. Most mutations occur de novo during spermatogenesis. Located at Xq28, MECP2 is subject to X inactivation, and affected females are mosaic. Rare hemizygous males suffer from a severe congenital encephalopathy. Methods To identify pathways mis-regulated by MeCP2 deficiency, microarray-based global gene expression studies were carried out on cerebellum of Mecp2 mutant mice. We compared transcript levels in mutant/wildtype male sibs of two different MeCP2-deficient mouse models at 2, 4 and 8 weeks of age. Increased transcript levels were evaluated by real-time quan...

  14. The human AlkB homologue 4 interacts with proteins associated with transcription (expression) ArrayExpress

    ID: E-GEOD-39127

    Description: nism. Humans possess nine AlkB homologues (ALKBH1-8 and FTO). ALKBH2 and ALKBH3 display demethylase activities corresponding to that of AlkB, and both ALKBH8 and FTO are RNA modification enzymes. The biochemical functions of the rest of the homologues are still unknown. To increase our knowledge on the functions of ALKBH4 and ALKBH7 we have here performed ...

  15. The human AlkB homologue 4 interacts with proteins associated with transcription (methylation) ArrayExpress

    ID: E-GEOD-39126

    Description: nism. Humans possess nine AlkB homologues (ALKBH1-8 and FTO). ALKBH2 and ALKBH3 display demethylase activities corresponding to that of AlkB, and both ALKBH8 and FTO are RNA modification enzymes. The biochemical functions of the rest of the homologues are still unknown. To increase our knowledge on the functions of ALKBH4 and ALKBH7 we have here performed ...

  16. The human AlkB homologue 4 interacts with proteins associated with transcription (methylation) BioProject

    ID: PRJNA170062

    Keywords: Epigenomics

    Access Type: download

  17. Cerebellar gene expression profiles of mouse models for Rett Syndrome reveal MeCP2 targets BioProject

    ID: PRJNA102063

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: and seizures. Most mutations occur de novo during spermatogenesis. Located at Xq28, MECP2 is subject to X inactivation, and affected females are mosaic. Rare hemizygous males suffer from a severe congenital encephalopathy. Methods To identify pathways mis-regulated by MeCP2 deficiency, microarray-based global gene expression studies were carried out on cerebellum of Mecp2 mutant mice. We compared transcript levels in mutant/wildtype male sibs of two different MeCP2-deficient mouse models at 2, 4 and 8 weeks of age. Increased transcript levels were evaluated by real-time quan...
  18. The human AlkB homologue 4 interacts with proteins associated with transcription (expression) OmicsDI

    ID: E-GEOD-39127

    Date Released: 06-02-2014

    Description: nism. Humans possess nine AlkB homologues (ALKBH1-8 and FTO). ALKBH2 and ALKBH3 display demethylase activities corresponding to that of AlkB, and both ALKBH8 and FTO are RNA modification enzymes. The biochemical functions of the rest of the homologues are still unknown. To increase our knowledge on the functions of ALKBH4 and ALKBH7 we have here performed ...

  19. The human AlkB homologue 4 interacts with proteins associated with transcription (methylation) OmicsDI

    ID: E-GEOD-39126

    Date Released: 06-02-2014

    Description: nism. Humans possess nine AlkB homologues (ALKBH1-8 and FTO). ALKBH2 and ALKBH3 display demethylase activities corresponding to that of AlkB, and both ALKBH8 and FTO are RNA modification enzymes. The biochemical functions of the rest of the homologues are still unknown. To increase our knowledge on the functions of ALKBH4 and ALKBH7 we have here performed ...

  20. Germ cell nuclear factor regulates gametogenesis in developing gonads BioProject

    ID: PRJNA246563

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ls correlates with the expression of pluripotency-associated genes, such as Oct4, Sox2, and Nanog, as well as the early meiotic marker gene Stra8. To elucidate the role of Gcnf during mouse germ cell differentiation, we generated an ex vivo Gcnf-knockdown model in combination with a regulated CreLox mutation of Gcnf. Lack of Gcnf impairs normal spermatogenesis and oogenesis in vivo, as well as the derivation of germ cells from embryonic stem cells (ESCs) in vitro. Inactivation of the Gcnf gene in vivo leads to loss of repression of Oct4 expression in both male and female gonads. For RNA isolation, PGCs were sorted by FACS, collected by centrifugation, lyse...

Displaying 20 of 25 results for "SPATA8"