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Displaying 20 of 38 results for "SOX5"
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  1. 3D Solution NMR Structure of the M9I Mutant of the HMG-Box Domain of the Human Male Sex Determining Factor SRY Complexed to DNA PDB

    ID: PDB:1J47

    Description: SEX-DETERMINING REGION Y PROTEIN/DNA COMPLEX

  2. 3D Solution NMR Structure of the Wild Type HMG-BOX Domain of the Human Male Sex Determining Factor Sry Complexed to DNA PDB

    ID: PDB:1J46

    Description: SEX-DETERMINING REGION Y PROTEIN/DNA COMPLEX

  3. RNA-seq of SOX5 overexpressing primary human neuronal progenitors BioProject

    ID: PRJNA350168

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis (RNA-Seq) BioProject

    ID: PRJNA287714

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis (ChIP-Seq) BioProject

    ID: PRJNA287713

    Keywords: Epigenomics

    Access Type: download

  6. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis ArrayExpress

    ID: E-GEOD-70144

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  7. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis (ChIP-Seq) ArrayExpress

    ID: E-GEOD-70143

    Description: tional activator required for chondrogenesis, and SOX5 and SOX6 are closely related DNA-binding proteins that critically enhance its function. We used RNA-seq to charatierize a rat chondrosarcoma (RCS...

  8. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis (RNA-Seq) ArrayExpress

    ID: E-GEOD-70142

    Description: tional activator required for chondrogenesis, and SOX5 and SOX6 are closely related DNA-binding proteins that critically enhance its function. We used RNA-seq to charatierize a rat chondrosarcoma (RCS...

  9. () Validation of murine Sox5 enrichment in library-transduced and polyhema-selected MDCK cells Figshare

    ID: doi:10.6084/M9.FIGSHARE.83930.V1

    Release Date: 05-22-2016

    Description: indicated. () Western blot analysis of human Sox-5 protein expression in hSOX5-transduced MDCK cells or in GFP-transduced control cells, as indicated. Anti-β-actin was used as loading control. () Growth curve of GFP- and SOX5-transduced MDCK cells on plastic (adherent) and polyhema (suspension). The -...

  10. Transcription profiling of human mesenchymal stem cells transfected with adenoviruses carrying the SOX trio or LacZ control to identify target molecul... ArrayExpress

    ID: E-MEXP-960

    Description: identify target molecules of the SOX trio (SOX9, SOX5 and SOX6). hMSC were transfected with the adenoviruses carrying the SOX trio or the LacZ-control, and total RNA was isolated after 2 weeks of culture....

  11. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis (ChIP-Seq) OmicsDI

    ID: E-GEOD-70143

    Date Released: 06-27-2015

    Description: tional activator required for chondrogenesis, and SOX5 and SOX6 are closely related DNA-binding proteins that critically enhance its function. We used RNA-seq to charatierize a rat chondrosarcoma (RCS...

  12. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis (RNA-Seq) OmicsDI

    ID: E-GEOD-70142

    Date Released: 06-27-2015

    Description: tional activator required for chondrogenesis, and SOX5 and SOX6 are closely related DNA-binding proteins that critically enhance its function. We used RNA-seq to charatierize a rat chondrosarcoma (RCS...

  13. The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis OmicsDI

    ID: E-GEOD-70144

    Date Released: 06-27-2015

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  14. SOX5_XENTR UniProt:Swiss-Prot

    ID: B3DM43

    Description: Transcription factor Sox-5 HMG box Gln-rich

  15. Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex ArrayExpress

    ID: E-GEOD-22371

    Description: ely, genes that implement caudal cortex and layer 5 identity, such as Bhlhb5 and Fezf2, were up-regulated in Tbr1 mutants. Tbr1 implements frontal identity in part by direct promoter binding and activation of Auts2, a frontal cortex gene implicated in autism. Tbr1 regulates laminar identity in part by downstream activation or maintenance of Sox5, an important transcription factor controlling neuronal migration and corticofugal axon projections. Similar to Sox5 mutants, Tbr1 mutants exhibit ectopic axon projections to the hypothalamus and cerebral peduncle. Together, our findings show that Tbr1 coordinately regulates regional and laminar identity of post...

  16. Transcription profiling of human mesenchymal stem cells transfected with adenoviruses carrying the SOX trio or LacZ control to identify target molecul... OmicsDI

    ID: E-MEXP-960

    Date Released: 05-25-2012

    Description: identify target molecules of the SOX trio (SOX9, SOX5 and SOX6). hMSC were transfected with the adenoviruses carrying the SOX trio or the LacZ-control, and total RNA was isolated after 2 weeks of culture....

  17. Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex OmicsDI

    ID: E-GEOD-22371

    Date Released: 03-27-2012

    Description: ely, genes that implement caudal cortex and layer 5 identity, such as Bhlhb5 and Fezf2, were up-regulated in Tbr1 mutants. Tbr1 implements frontal identity in part by direct promoter binding and activation of Auts2, a frontal cortex gene implicated in autism. Tbr1 regulates laminar identity in part by downstream activation or maintenance of Sox5, an important transcription factor controlling neuronal migration and corticofugal axon projections. Similar to Sox5 mutants, Tbr1 mutants exhibit ectopic axon projections to the hypothalamus and cerebral peduncle. Together, our findings show that Tbr1 coordinately regulates regional and laminar identity of post...

  18. Chondrogenic differentiation of human bone marrow-derived mesenchymal stem cells in self-gelling alginate discs reveals novel chondrogenic signature g... ArrayExpress

    ID: E-GEOD-40175

    Description: ing type II collagen (COL2), COL10, aggrecan, and SOX5, 6, and 9 were greatly elevated already at day 7, whereas COL1 and versican mRNA were gradually reduced. COL2 and aggrecan were dispersed throughout the extracellular matrix at day 21, whereas COL10 distribution was mainly intra/pericellular. COL1 seemed to be produced by only some of the cells. SOX proteins were predominantly localized in the nuclei. Then, using microarray analysis, we identified a signature cluster of extracellular matrix and transcription factor genes upregulated during chondrogenesis similar to COL2A1, and clusters of genes involved in immune responses, blood vessel development, and cell adhesion downregulated similar to the chemokine CXCL12. An...

  19. Detection of genome-wide copy number variations in two chicken lines divergently selected for abdominal fat content ArrayExpress

    ID: E-GEOD-58551

    Description: n and 27 both (i.e. loss and gain within the same region) events in the lean line, and 143 loss, 25 gain and 20 both events in the fat line. Ten CNVRs were chosen for the validation experiment using qPCR method, and all of them were confirmed in at least one qPCR assay. We found a total of 886 genes located within these CNVRs, and Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses showed they could play various roles in a number of biological processes. Integrating the results of CNVRs, known quantitative trait loci (QTL) and selective sweeps for abdominal fat content suggested that some genes (including SLC9A3, GNAL, SPOCK3, ANXA10, HELIOS, MYLK, CCDC14, SPAG9, SOX5, VSNL1, SMC6, GEN1, MSGN1 and ZPAX) may be important for abdominal fat deposition in the chicken. Conclusions: Our study provided a genome-wide CNVR map of the chicken genome, thereby contributing to our understanding of genomic structural variations and their potential roles in abdominal fat content in the chicken. In total, 475 birds (203 and 272 individuals from the lean and fat lines, respectively) from the 11th generation population of Northeast Agricultural University broiler lines divergently selected for abdominal fat content (NEAUHLF)...

  20. Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex BioProject

    ID: PRJNA127649

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ely, genes that implement caudal cortex and layer 5 identity, such as Bhlhb5 and Fezf2, were up-regulated in Tbr1 mutants. Tbr1 implements frontal identity in part by direct promoter binding and activation of Auts2, a frontal cortex gene implicated in autism. Tbr1 regulates laminar identity in part by downstream activation or maintenance of Sox5, an important transcription factor controlling neuronal migration and corticofugal axon projections. Similar to Sox5 mutants, Tbr1 mutants exhibit ectopic axon projections to the hypothalamus and cerebral peduncle. Together, our findings show that Tbr1 coordinately regulates regional and laminar identity of post...

Displaying 20 of 38 results for "SOX5"