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Displaying 20 of 22 results for "SOX18"
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  1. Sox18 ChIP-seq in HUVECs BioProject

    ID: PRJEB12767

    Keywords: Other

    Access Type: download

  2. Sox18 regulated genes BioProject

    ID: PRJNA102385

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Sox18 ChIP-seq in HUVECs ArrayExpress

    ID: E-MTAB-4481

    Description: We investigated SOX18 binding events on the chromatin under basal conditions in human umbilical vein endothelial cells, upon overexpression of mous...

  4. Structure of SOX18-HMG/PROX1-DNA PDB

    ID: PDB:4Y60

    Description: SOX18/DNA Complex

  5. Sox18 regulated genes ArrayExpress

    ID: E-GEOD-8952

    Description: Study of Sox18 regulated genes: Human umbilical vein endothelial cells (HUVEC) were either transduced with adenoviral vectors expressing

  6. RNA-seq in HUVECs overexpressing Sox18 and treated with Sm4 BioProject

    ID: PRJEB12918

    Keywords: Other

    Access Type: download

  7. RNA-seq in HUVECs overexpressing Sox18 and treated with Sm4 ArrayExpress

    ID: E-MTAB-4511

    Description: VECs under basal conditions and overexpression of Sox18 in presence or absence of small molecule protein-protein disruptor Sm4. Various RNA fractions were prepared and sequenced in order to characterise Sox18

  8. Sox18 regulated genes OmicsDI

    ID: E-GEOD-8952

    Date Released: 01-30-2012

    Description: Study of Sox18 regulated genes: Human umbilical vein endothelial cells (HUVEC) were either transduced with adenoviral vectors expressing

  9. SOX18_XENTR UniProt:Swiss-Prot

    ID: B3DLD3

    Description: Transcription factor Sox-18 Sox C-terminal HMG box

  10. Expression data during vascular endothelial cells differentiation from mouse embryonic stem cells OmicsDI

    ID: E-GEOD-76964

    Date Released: 07-18-2016

    Description: h peculiar to ECs. We find Gata2, Fli1, Sox7, and Sox18 are master regulators from genetic and epigenetic data, these genes were induced after Etv2 activation. These genes have specific histone modification pattern which is repressed by H3K27me3 modification at Flk-sorted mesoderm and changed to the bivalent (H3K4me3 and H3K27me3 both positive) state rapidly after vascular endothelial cells growth factor (VEGF) stimuli. Using a previously reported ECs differentiation model, we demonstrate that four transcription factors are critical for ECs specific gene expressions and efficient differentiation. Moreover, from knockdown e...

  11. The persistent milk yield response to frequent milking during early lactation is associated with persistent changes in mammary gene expression ArrayExpress

    ID: E-GEOD-27851

    Description: d that the differential expression (4X vs. 2X) of 18 genes was significantly affected by DIM. Within the group of 18 differentially expressed genes, we identified a cluster of 15 genes with a similar temporal pattern of differential expression. Nine of the genes in the cluster remained differentially expressed at 40 DIM, indicating that they may be involved in the persistent milk yield response. Among the genes in the cluster were chitinase 3-like (CHI3L)-1, clusterin, early growth response (EGR)-1, and sex determining region Y-box (SOX)-4. These genes have been associated with mammary development, differentiation and remodeling; all of which may be functionally related to the increase in milk yield. We conclude that frequent milking during early lactation does not alter mammary growth but is associated with changes in mammary expression of 18 genes. Future experiments will determine the function of these genes in the mammary gland, and will clarify their role in the autocrine regulation of milk production and long-term alteration of mammary function. 36 samples from 6 cows; 3 timepoints...

  12. Expression data during vascular endothelial cells differentiation from mouse embryonic stem cells ArrayExpress

    ID: E-GEOD-76964

    Description: h peculiar to ECs. We find Gata2, Fli1, Sox7, and Sox18 are master regulators from genetic and epigenetic data, these genes were induced after Etv2 activation. These genes have specific histone modification pattern which is repressed by H3K27me3 modification at Flk-sorted mesoderm and changed to the bivalent (H3K4me3 and H3K27me3 both positive) state rapidly after vascular endothelial cells growth factor (VEGF) stimuli. Using a previously reported ECs differentiation model, we demonstrate that four transcription factors are critical for ECs specific gene expressions and efficient differentiation. Moreover, from knockdown e...

  13. e 5: of Methylome analysis for spina bifida shows SOX18 hypomethylation as a risk factor with evidence for a complex (epi)genetic interplay to affect neural tube development... Figshare

    ID: doi:10.6084/M9.FIGSHARE.C.3604349_D2

    Release Date: 12-14-2016

    Description: Table S1รข S10. (XLSX 1175 kb)

  14. Analysis of Gene Expression in the Chicken Otocyst ArrayExpress

    ID: E-GEOD-27176

    Description: genes, such as Sox4, Sox5, Sox7, Sox8, Sox11, and Sox18, which previously were not known to be expressed in the developing inner ear. Despite its obvious limitation of not being all-inclusive, the generated otocyst SAGE library is a practical bioinformatics tool to study otocyst gene expression and to identify candidate genes for developmental studies. Otocysts were dissected from HH stage 18-19 chicken embryos, total RNA was extracted, and subjected to a commercial long-SAGE protocol, resulting in a library of concatemerized tags. 3,512 individual clones of SAGE concatemers were sequenced resulting in 39,326 17-bp tags with tag counts up to 718 for the most abundant tag; 3,292 tags that were represented between two and five times, whereas the majority of tags (11,717) were only found once. Overall, we identified 16,008 unique sequence tags....

  15. Analysis of Gene Expression in the Chicken Otocyst BioProject

    ID: PRJNA137363

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: genes, such as Sox4, Sox5, Sox7, Sox8, Sox11, and Sox18, which previously were not known to be expressed in the developing inner ear. Despite its obvious limitation of not being all-inclusive, the generated otocyst SAGE library is a practical bioinformatics tool to study otocyst gene expression and to identify candidate genes for developmental studies. Overall design: Otocysts were dissected from HH stage 18-19 chicken embryos, total RNA was extracted, and subjected to a commercial long-SAGE protocol, resulting in a library of concatemerized tags. 3,512 individual clones of SAGE concatemers were sequenced resulting in 39,326 17-bp tags with tag counts up to 718 for the most abundant tag; 3,292 tags that were represented between two and five times, whereas the majority of tags (11,717) were only found once. Overall, we identified 16,008 unique sequence tags....
  16. Expression data during vascular endothelial cells differentiation from mouse embryonic stem cells BioProject

    ID: PRJNA309159

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: h peculiar to ECs. We find Gata2, Fli1, Sox7, and Sox18 are master regulators from genetic and epigenetic data, these genes were induced after Etv2 activation. These genes have specific histone modification pattern which is repressed by H3K27me3 modification at Flk-sorted mesoderm and changed to the bivalent (H3K4me3 and H3K27me3 both positive) state rapidly after vascular endothelial cells growth factor (VEGF) stimuli. Using a previously reported ECs differentiation model, we demonstrate that four transcription factors are critical for ECs specific gene expressions and efficient differentiation. Moreover, from knockdown e...
  17. Analysis of Gene Expression in the Chicken Otocyst OmicsDI

    ID: E-GEOD-27176

    Date Released: 03-01-2011

    Description: genes, such as Sox4, Sox5, Sox7, Sox8, Sox11, and Sox18, which previously were not known to be expressed in the developing inner ear. Despite its obvious limitation of not being all-inclusive, the generated otocyst SAGE library is a practical bioinformatics tool to study otocyst gene expression and to identify candidate genes for developmental studies. Otocysts were dissected from HH stage 18-19 chicken embryos, total RNA was extracted, and subjected to a commercial long-SAGE protocol, resulting in a library of concatemerized tags. 3,512 individual clones of SAGE concatemers were sequenced resulting in 39,326 17-bp tags with tag counts up to 718 for the most abundant tag; 3,292 tags that were represented between two and five times, whereas the majority of tags (11,717) were only found once. Overall, we identified 16,008 unique sequence tags....

  18. Using Oligo Array Analysis to Determine Genes of Importance in the Meninges and Associated Vasculature Function and their Sensitivity to Amphetamine T... ArrayExpress

    ID: E-GEOD-23093

    Description: ction and damage than EIH. The BBB-related genes Sox18 and Cldn5 expression decreased more with AMPH than EIH, and Cldn 9 and Esam were increase only by AMPH. It is not known how these changes affect BBB function and integrity. Gene expression patterns in MAV were compared to two regions of brain (striatum and parietal cortex) to identify genes important to MAV function and determine whether their expressions were sensitive to a neurotoxic exposure to amphetamine....

  19. Using Oligo Array Analysis to Determine Genes of Importance in the Meninges and Associated Vasculature Function and their Sensitivity to Amphetamine T... OmicsDI

    ID: E-GEOD-23093

    Date Released: 06-10-2011

    Description: ction and damage than EIH. The BBB-related genes Sox18 and Cldn5 expression decreased more with AMPH than EIH, and Cldn 9 and Esam were increase only by AMPH. It is not known how these changes affect BBB function and integrity. Gene expression patterns in MAV were compared to two regions of brain (striatum and parietal cortex) to identify genes important to MAV function and determine whether their expressions were sensitive to a neurotoxic exposure to amphetamine....

  20. Histone modification (H3K4me3 and H3K27me3) during vascular endothelial cell differentiation from mouse embryonic stem cells BioProject

    ID: PRJNA374538

    Keywords: Epigenomics

    Access Type: download

    dataset.description: to ECs. We determined that Gata2, Fli1, Sox7, and Sox18 are master regulators of EC induced following expression of the hemangioblast commitment pioneer factor, Etv2. These master regulator gene loci were repressed by H3K27me3 under the mesoderm period, but rapidly transitioned to the histone modification switching from H3K27me3 to H3K4me3 after treatment with vascular endothelial growth factor (VEGF). SiRNA knockdown experiments indicated that these regulators are indispensable not only for proper EC differentiation but also for blocking the commitment to other closely aligned lineages. Collectively, our detailed epigenetic analysis might provide an advanced model for understanding temporal regulation of...

Displaying 20 of 22 results for "SOX18"