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Displaying 20 of 637 results for "SMC3"
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  1. cohesin Smc3-HD:Scc1-N complex from yeast PDB

    ID: PDB:4UX3

    Description: STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3, MITOTIC CHROMOSOME DETERM...

  2. SMC hinge heterodimer (Mouse) PDB

    ID: PDB:2WD5

    Description: STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 1A, STRUCTURAL

  3. The Smc3 deacetylase Hos1 closes the cohesin acetylation cycle BioProject

    ID: PRJNA128727

    Keywords: Epigenomics

    Access Type: download

  4. Releasing activity disengages cohesin’s Smc3/Scc1 interface in a process blocked by acetylation BioProject

    ID: PRJNA308862

    Keywords: Epigenomics

    Access Type: download

  5. Releasing activity disengages cohesin’s Smc3/Scc1 interface in a process blocked by acetylation ArrayExpress

    ID: E-GEOD-76890

    Description: e ring formed between cohesin’s Scc1, Smc1, and Smc3 subunits is generated during S and eventually destroyed at anaphase through cleavage of Scc1 by separase. Throughout the cell cycle, cohesin’s association with chromosomes is controlled by...

  6. SMC3_SCHPO UniProt:Swiss-Prot

    ID: O42649

    Description: Structural maintenance of chromosomes protein 3 ATP Flexible hinge Ala/Asp...

  7. SMC3_PONAB UniProt:Swiss-Prot

    ID: Q5R4K5

    Description: Structural maintenance of chromosomes protein 3 ATP Flexible hinge Ala/Asp...

  8. SMC3_PLAF7 UniProt:Swiss-Prot

    ID: Q8I1U7

    Description: Structural maintenance of chromosomes protein 3 homolog ATP Flexible hinge...

  9. SMC3_BOVIN UniProt:Swiss-Prot

    ID: O97594

    Description: Structural maintenance of chromosomes protein 3 ATP Flexible hinge Ala/Asp...

  10. SMC3_RAT UniProt:Swiss-Prot

    ID: P97690

    Description: Structural maintenance of chromosomes protein 3 ATP Flexible hinge Ala/Asp...

  11. SMC5_SCHPO UniProt:Swiss-Prot

    ID: O13710

    Description: Structural maintenance of chromosomes protein 5 ATP Flexible hinge Ala/Asp-rich (DA-box)

  12. Releasing activity disengages cohesin’s Smc3/Scc1 interface in a process blocked by acetylation OmicsDI

    ID: E-GEOD-76890

    Date Released: 03-24-2016

    Description: e ring formed between cohesin’s Scc1, Smc1, and Smc3 subunits is generated during S and eventually destroyed at anaphase through cleavage of Scc1 by separase. Throughout the cell cycle, cohesin’s association with chromosomes is controlled by...

  13. Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis [ATAC-Seq] BioProject

    ID: PRJNA296386

    Keywords: Epigenomics

    Access Type: download

    dataset.description: progenitors. We investigated the consequences of Smc3 deletion in normal and malignant hematopoiesis. Bi-allelic Smc3 loss induced bone marrow aplasia with premature sister chromatid separation, and revealed an absolute requirement for cohesin in hematopoietic stem cell function. In contrast, Smc3 haploinsufficiency increased self-renewal in vitro and in vivo including competitive transplantation. Smc3 haploinsufficiency reduced coordinated transcriptional output, including reduced express...
  14. Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis [ATAC-Seq] OmicsDI

    ID: E-GEOD-73215

    Date Released: 09-26-2015

    Description: progenitors. We investigated the consequences of Smc3 deletion in normal and malignant hematopoiesis. Bi-allelic Smc3 loss induced bone marrow aplasia with premature sister chromatid separation, and revealed an absolute requirement for cohesin in hematopoietic stem cell function. In contrast, Smc3 haploinsufficiency increased self-renewal in vitro and in vivo including competitive transplantation. Smc3 haploinsufficiency reduced coordinated transcriptional output, including reduced express...

  15. Cohesin is required for expression of the estrogen receptor-alpha (ESR1) gene BioProject

    ID: PRJNA167524

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: udy we show that depletion of the cohesin subunit SMC3 or the Mediator subunit MED12 significantly impairs the ERα-regulated transcriptome. Surprisingly, SMC3 depletion ap...
  16. Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis [RNA-Seq] BioProject

    ID: PRJNA296385

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: progenitors. We investigated the consequences of Smc3 deletion in normal and malignant hematopoiesis. Bi-allelic Smc3 loss induced bone marrow aplasia with premature sister chromatid separation, and revealed an absolute requirement for cohesin in hematopoietic stem cell function. In contrast, Smc3 haploinsufficiency increased self-renewal in vitro and in vivo including competitive transplantation. Smc3 haploinsufficiency reduced coordinated transcriptional output, including reduced express...
  17. ChIP-Seq on Cohesin mutant TF-1 Cell Line BioProject

    ID: PRJNA296372

    Keywords: Epigenomics

    Access Type: download

    dataset.description: Understanding the binding of GATA2, RUNX1 and SMC3 in RAD21 WT vs. mutant TF-1 Cells Overall design: We examined GATA2, RUNX1 and SMC3 using ChIP-seq in TF-1 ...
  18. ChIP-Seq on Cohesin mutant TF-1 Cell Line ArrayExpress

    ID: E-GEOD-73207

    Description: Understanding the binding of GATA2, RUNX1 and SMC3 in RAD21 WT vs. mutant TF-1 Cells We examined GATA2, RUNX1 and SMC3 using ChIP-seq in TF-1 erythroleukemia ...

  19. Dose-dependent role of the cohesin complex in normal and malignant hematopoiesis [ATAC-Seq] ArrayExpress

    ID: E-GEOD-73215

    Description: progenitors. We investigated the consequences of Smc3 deletion in normal and malignant hematopoiesis. Bi-allelic Smc3 loss induced bone marrow aplasia with premature sister chromatid separation, and revealed an absolute requirement for cohesin in hematopoietic stem cell function. In contrast, Smc3 haploinsufficiency increased self-renewal in vitro and in vivo including competitive transplantation. Smc3 haploinsufficiency reduced coordinated transcriptional output, including reduced express...

  20. Using Model Organism Saccharomyces Cerevisiae to Evaluate the Differential Effects of ELF-MF and RF-EMF exposure on Global Gene Expression BioProject

    ID: PRJNA137131

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: n experiments found that only five were affected: structural maintenance of chromosomes 3-gene (SMC3), aquaporin 2 –gene (AQY2), halotolerance protein 9 –gene (HAL9), yet another kinase 1 -gene (YAK1) and one of unknown function gene (open reading frame: YJL171C) (P<0.05). Overall, this study has demonstrated that the yeast cells did not respond to 50 Hz ELF-MF and that the response to RF-EMF is limited to only five genes. The biological consequences of the observed gene expression changes induced by RF-EMF await further investigation. Overall design: The yeast cells were exposed to 0.4 mT 50 Hz ELF-MF or 1800 MHz RF-EMF at a specific absorption rate of 3.5 W/kg for 6 hours....

Displaying 20 of 637 results for "SMC3"