SMAD7 | bioCADDIE Data Discovery Index
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Displaying 20 of 64 results for "SMAD7"
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  1. YAP WW1 in complex with a Smad7 derived peptide PDB

    ID: PDB:2LTW

    Description: Yorkie homolog, Smad7 derived peptide

  2. Role of Smad7 in Hematopoietic (M-O7e) and Non-Hematopoietic (PG13) Stem Cells BioProject

    ID: PRJNA93955

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Smurf2 WW3 domain in complex with a Smad7 derived peptide PDB

    ID: PDB:2LTZ

    Description: E3 ubiquitin-protein ligase SMURF2, Smad7 derived peptide

  4. Smurf1 WW2 domain in complex with a Smad7 derived peptide PDB

    ID: PDB:2LTX

    Description: E3 ubiquitin-protein ligase SMURF1, Smad7 derived peptide

  5. Solution structure of Smurf2 WW3 domain-Smad7 PY peptide complex PDB

    ID: PDB:2DJY

    Description: Smad ubiquitination regulatory factor 2 (E.C.6.3.2.-), Mothers against decapentaplegic homolog 7

  6. YAP WW2 in complex with a Smad7 derived peptide PDB

    ID: PDB:2LTV

    Description: Yorkie homolog, Mothers against decapentaplegic homolog 7

  7. NEDD4L WW2 domain in complex with a Smad7 derived peptide PDB

    ID: PDB:2LTY

    Description: E3 ubiquitin-protein ligase NEDD4-like, Mothers against decapentaplegic homolog 7

  8. cell lines that have been transduced with either Smad7 recombinant retroviral vector vs control... ArrayExpress

    ID: E-GEOD-3771

    Description: Smad7 is a member of the TGF-B superfamily that plays a signigicant role in fate determination of hematopoietic ...

  9. SCGB3A2 suppresses bleomycin-induced pulmonary fibrosis through activation of STAT1 and up-regulation of SMAD7  BioProject

    ID: PRJNA126181

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Homo sapiens : Homo sapiens Transcriptome or Gene expression BioProject

    ID: PRJNA326598

    Keywords: transcriptome

    Access Type: download

    dataset.description: RNA-seq analysis to study the effect of SMAD7 in Acute Lymphoblastic Leukaemia.
  11. Solution Structure of Smurf2 WW2 and WW3 bound to Smad7 PY motif containing peptide PDB

    ID: PDB:2KXQ

    Description: E3 ubiquitin-protein ligase SMURF2, S7PY

  12. cell lines that have been transduced with either Smad7 recombinant retroviral vector vs control... OmicsDI

    ID: E-GEOD-3771

    Date Released: 10-12-2011

    Description: Smad7 is a member of the TGF-B superfamily that plays a signigicant role in fate determination of hematopoietic ...

  13. SCGB3A2 suppresses bleomycin-induced pulmonary fibrosis through activation of STAT1 and up-regulation of SMAD7  ArrayExpress

    ID: E-GEOD-21560

    Description: We report for the first time that secretoglobin (SCGB) 3A2, a novel cytokine-like molecule, predominantly expressed in pulmonary airways epithelium, d...

  14. Identification of miR-181a target genes in Epithelial Ovarian Cancer ArrayExpress

    ID: E-GEOD-52077

    Description: gh decreased TGF-β signaling. Our data confirmed Smad7 as a functional target through which TGF-β-mediated EMT occurs; re-expression of Smad7 lacking its 3'UTR was able to rescue miR-181a-mediated phenotypes, deeming Smad7 as a critical mediator of miR-181a-induced EMT. Other recent studies support the crucial role(s) that miRNAs play in mediating EMT and consequent aggressive disease traits. For example, the miR-106b-25 cluster has also been shown to target Smad7 and mediate TGF-β-induced EMT downstream to Six1 in breast cancer34. miR-9 directly targets E-cadherin and inhibition of miR-9 had led to an inhibition of metastasis35. Conversely, the miR-200 and -205 family

  15. Liver expression of Bmp6, Smad7, Id1 and Atoh8 is regulated by iron stores BioProject

    ID: PRJNA108071

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Genome-wide mapping of Olig2 targets in primary oligodendrocytes ArrayExpress

    ID: E-GEOD-40506

    Description: functionally linked by the Olig1/2 common target Smad-interacting protein-1 (Sip1). We demonstrate that Sip1 is an essential modulator of CNS myelination. Sip1 represses differentiation inhibitory signals by antagonizing BMP receptor-activated Smad activity while activating crucial oligodendrocyte-promoting factors. Importantly, a key Sip1-activated target, Smad7, is required for oligodendrocyte differentiation and partially rescues differentiation defects caused by Sip1 loss. Smad7 promotes myelination by blocking the BMP- and β-catenin-negative...

  17. Identification of miR-181a target genes in Epithelial Ovarian Cancer OmicsDI

    ID: E-GEOD-52077

    Date Released: 06-03-2014

    Description: gh decreased TGF-β signaling. Our data confirmed Smad7 as a functional target through which TGF-β-mediated EMT occurs; re-expression of Smad7 lacking its 3'UTR was able to rescue miR-181a-mediated phenotypes, deeming Smad7 as a critical mediator of miR-181a-induced EMT. Other recent studies support the crucial role(s) that miRNAs play in mediating EMT and consequent aggressive disease traits. For example, the miR-106b-25 cluster has also been shown to target Smad7 and mediate TGF-β-induced EMT downstream to Six1 in breast cancer34. miR-9 directly targets E-cadherin and inhibition of miR-9 had led to an inhibition of metastasis35. Conversely, the miR-200 and -205 family

  18. Identification of miR-181a target genes in Epithelial Ovarian Cancer BioProject

    ID: PRJNA226708

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: gh decreased TGF-β signaling. Our data confirmed Smad7 as a functional target through which TGF-β-mediated EMT occurs; re-expression of Smad7 lacking its 3'UTR was able to rescue miR-181a-mediated phenotypes, deeming Smad7 as a critical mediator of miR-181a-induced EMT. Other recent studies support the crucial role(s) that miRNAs play in mediating EMT and consequent aggressive disease traits. For example, the miR-106b-25 cluster has also been shown to target Smad7 and mediate TGF-β-induced EMT downstream to Six1 in breast cancer34. miR-9 directly targets E-cadherin and inhibition of miR-9 had led to an inhibition of metastasis35. Conversely, the miR-200 and -205 family
  19. Induction of cells expressing markers of GABAergic neurons by transcription factors (mRNA) ArrayExpress

    ID: E-GEOD-78949

    Description: . After induction for 6 days four of them (Ascl1, Smad7, Nr2f1, and Ascl2) generated a high proportion (>35%) of cells with neural progenitor marker PSA-NCAM and clear neural morphology on day 14. The capacity of these TFs to induce neural differentiation is inferred to be most likely linked to early activation of the Notch signaling pathway. Among the neuron-like cells, GABA-positive cells were most abundant (32-97% for 4 top TFs), whereas Isl1-positive cells and TH-positive cells were less abundant (<12% and <5%, respectively). Enrichment of cells obtained with the induction of Ascl1, Smad7, and Nr2f1 using beads with anti-PSA-NCAM antibody resulted in essentially pure population of neuron-like cells with expression profiles similar to neural tissues and highly expressed markers of...

  20. Gene expression networks in COPD: microRNA and mRNA regulation ArrayExpress

    ID: E-GEOD-38974

    Description: ressed within GOLD classes of COPD. Expression of SMAD7, which was validated as a target for miR-15b, was decreased in bronchial epithelial cells in COPD. Lung tissue from smokers with no evidence of obstructive lung disease and smokers with COPD was examined for miRNA and mRNA expression followed by validation. We then examined both miRNA and mRNA expression to enrich for relevant biological pathways...


Displaying 20 of 64 results for "SMAD7"