SLC45A2 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 5,205 results for "SLC45A2"
i
  1. Data from: A missense mutation in SLC45A2 is associated with albinism in several small long haired dog breeds Dryad

    DateIssued: 04-27-2015

    Description: Homozygosity for a large deletion in the solute carrier family 45, member 2 (...

  2. Supplemental Figure 1-A topology prediction comparison for SLC45A2 Dryad

    DateIssued: 03-20-2015

    Description: A topology prediction comparison for SLC45A2 was carried out using TMHMM (v. 2.0; http://www.cbs.dtu.dk/services/ TMHMM-2.0/). a) The topology prediction for a cream Po...

  3. SLC45A2 genotypes and phenotypes of albino and control drogs Dryad

    DateIssued: 03-20-2015

    Description: lbino dog: P250L in exon 3 and G493D in exon 7 of SLC45A2. The genotypes of all the tested albino and control dogs for these two mutations and their coat colours are included in the file....

  4. Supplemental Table 1:Primers, annealing temperatures and the fragment of the SLC45A2 gene amplified. Dryad

    DateIssued: 03-20-2015

  5. Dynamic changes in the functions of Klf5 in maturing mouse corneas revealed by the changes in its target genes at postnatal days 11 and 56 ArrayExpress

    ID: E-GEOD-36229

    Description: n WT corneas between PN11 and PN56, while that of solute carrier family members increased. Conclusions: Differences in PN11 and PN56 corneal Klf5-target genes reveal dynamic changes in Klf5 functions during corneal maturation. Klf4- and Klf5-target genes do not overlap, consistent with their non-redundant roles in the mouse cornea. Wild type and Klf5-conditional null mouse corneal gene expression at postnatal day-11 and -56 was compared by Affymetrix mouse whole genome 430 2 arrays. Four age-matched PN56 WT and Klf5CN mice, and 3 age-matched PN11 WT and Klf5CN mice each were used for comparison of corneal gene expression by microarrays. Two dissected corneas from each mouse were pooled for isolation of total RNA using the RNeasy Mini kit (Qiagen, Germantown, MD). The quality and integrity of the isolated total RNA was confirmed using an Agilent Bioanalyzer. Total RNAs were amplified and labeled using a 3' IVT Express Kit (Affymetrix Inc., Santa Clara, CA), and hybridized to Affymetrix MG 430 2 chips following the protocol suggested by the manufacturer....

  6. DNA microarray reveals novel genes induced by mechanical forces in fetal lung type II epithelial cells BioProject

    ID: PRJNA93603

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: by strain. Interestingly, several members of the solute carrier family of amino acid transporters, genes involved in amino acid synthesis and development, and amiloride-sensitive epithelial sodium channel gene were induced by strain. These results were confirmed by quantitative real-time polymerase chain reaction (qRT-PCR). Thus, this study identifies genes induced by strain that may be important for amino acid signaling pathways, protein synthesis and development in fetal type II cells. In addition, these data suggest that mechanical forces may contribute to facilitate lung fluid reabsorption in preparation for birth. Ta...
  7. Directed evolution of a B3 metallo-beta-lactamase AIM-1 PDB

    ID: PDB:4P62

    Description: AIM-1 mutant (L55Q F114L F230Y)

  8. Trans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene ArrayExpress

    ID: E-GEOD-10163

    Description: set contains Tyr, Tyrp1, Dct, Si, Melna, Slc24a5, Slc45a2, Slc24a4, Mitf, and Sox10, in addition to genes not previously attributed to pigmentation and genes with unknown function. Further evaluation of one gene in this cohort, Gpnmb, demonstrated an expression pattern similar to Dct, Si and Mitf. This expression is vastly reduced in MitfMi mutants embryos, indicating that it is dependent on Mitf for in vivo expression. Consistent with this notion, a highly-conserved MITF binding site resides directly upstream of human GPNMB, and deletion of this sequence dramatically reduces in vitro enhancer activity. Keywords: NIH embryo fibroblast cell line, melanocyte cell line, Ink4a, Tyrp1b, Rab38 A 32k expression arrays were generated by printing Oligo nucleotides from Operon Mouse oligo set (MV3) onto epoxy slides. Total RNA from immortalized melanocyte cell lines derived from C57BL/6J Ink4a-/- (melan-Ink4a-1), C57BL/6J Ink4a-/-; T...

  9. al Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157... PDB

    ID: PDB:4AX0

    Description: METALLO-BETA-LACTAMASE AIM-1

  10. ATG11_ARATH UniProt:Swiss-Prot

    ID: Q9SUG7

    Description: Autophagy-related protein 11 AIM (Atg8-family-interacting motif) AIM (Atg8-family-interacting motif) Ph...

  11. al Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157... PDB

    ID: PDB:4AX1

    Description: METALLO-BETA-LACTAMASE AIM-1

  12. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 PDB

    ID: PDB:4AWY

    Description: METALLO-BETA-LACTAMASE AIM-1

  13. Gene Expression profiles of colon from VhlF/F, VhlΔIE, VhlF/F/Apcmin/+, VhlΔIE/Apcmin/+ ArrayExpress

    ID: E-GEOD-36091

    Description: absorption transporter divalent metal transporter-1 (DMT-1) was a critical event in HIF-2α-mediated colon carcinogenesis. These data provide a mechanistic basis for the widely reported link between iron accumulation and colon cancer risk. Together, our findings demonstrate that a chronic increase in HIF-2α in the colon initiates pro-tumorigenic signaling which may have important implications in developing preventive and therapeutic strategies for colon cancer. Global gene expression profiling in colon RNAs isolated from 5-week-old VhlF/F (n=4, Shah 001), VhlF/F/Apcmin/+(n=3, Shah 003), VhlΔIE (n=3, Shah 002) and VhlΔIE/Apcmin/+ mice (n=5, Shah 004)....

  14. Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157 PDB

    ID: PDB:4AWZ

    Description: METALLO-BETA-LACTAMASE AIM-1

  15. Data from: Detecting genomic signatures of natural selection with principal component analysis: application to the 1000 Genomes data Dryad

    DateIssued: 03-03-2016

    Description: pproach, we consider the 1000 Genomes data (phase 1) considering 850 individuals coming from Africa, Asia, and Europe. The number of genetic variants is of the order of 36 millions obtained with a low-coverage sequencing depth (3×). The correlations between genetic variation and each principal component provide well-known targets for positive selection (EDAR, SLC24A5, SLC45A2, DARC), and also new candidate genes (APPBPP2, TP1A1, RTTN, KCNMA, MYO5C) and noncoding RNAs. In addition to identifying genes involved in biological adaptation, we identify two biological pathways involved in polygenic adaptation that are related to the innate immune system (beta defensins) and to lipid metabolism (fatty acid omega oxidation). An additional analysis of European data shows that a genome scan bas...

  16. Data from: MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration Dryad

    DateIssued: 01-27-2017

    Description: The melanocortin-1 receptor (MC1R) gene influences coloration by altering the expression of genes acting downstream in the melanin synthesis. MC1R b...

  17. Trans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene BioProject

    ID: PRJNA108359

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: set contains Tyr, Tyrp1, Dct, Si, Melna, Slc24a5, Slc45a2, Slc24a4, Mitf, and Sox10, in addition to genes not previously attributed to pigmentation and genes with unknown function. Further evaluation of one gene in this cohort, Gpnmb, demonstrated an expression pattern similar to Dct, Si and Mitf. This expression is vastly reduced in MitfMi mutants embryos, indicating that it is dependent on Mitf for in vivo expression. Consistent with this notion, a highly-conserved MITF binding site resides directly upstream of human GPNMB, and deletion of this sequence dramatically reduces in vitro enhancer activity. Keywords: NIH embryo fibroblast cell line, melanocyte cell line, Ink4a, Tyrp1b, Rab38 Overall design: A 32k expression arrays were generated by printing Oligo nucleotides from Operon Mouse oligo set (MV3) onto epoxy slides. Total RNA from immortalized melanocyte cell lines derived from C57BL/6J Ink4a-/- (melan-Ink4a-1), C57B...
  18. Trans. Profiling of Immortalized Melanocyte Cell Lines Identifies GPNMB as a Melanoblast-Expressed, MITF-Dependent Gene OmicsDI

    ID: E-GEOD-10163

    Date Released: 05-01-2014

    Description: set contains Tyr, Tyrp1, Dct, Si, Melna, Slc24a5, Slc45a2, Slc24a4, Mitf, and Sox10, in addition to genes not previously attributed to pigmentation and genes with unknown function. Further evaluation of one gene in this cohort, Gpnmb, demonstrated an expression pattern similar to Dct, Si and Mitf. This expression is vastly reduced in MitfMi mutants embryos, indicating that it is dependent on Mitf for in vivo expression. Consistent with this notion, a highly-conserved MITF binding site resides directly upstream of human GPNMB, and deletion of this sequence dramatically reduces in vitro enhancer activity. Keywords: NIH embryo fibroblast cell line, melanocyte cell line, Ink4a, Tyrp1b, Rab38 A 32k expression arrays were generated by printing Oligo nucleotides from Operon Mouse oligo set (MV3) onto epoxy slides. Total RNA from immortalized melanocyte cell lines derived from C57BL/6J Ink4a-/- (melan-Ink4a-1), C57BL/6J Ink4a-/-; T...

  19. Crystal structure of Saccharomyces cerevisiae Atg8 complexed with Atg32 AIM PDB

    ID: PDB:3VXW

    Description: Autophagy-related protein 8, Peptide from Autophagy-related protein 32

  20. Affect Intensity Measure (CAPS-AIM module) Dataverse

    Description: ly experiences his or her emotions. Items for the AIM were based on a definition which emphasized the distinction between frequency and intensity of experienced emotion. It is assumed that individuals who experience strong positive affect will also experience strong negative affect. Rs respond to the items on a six-point s...

    Release Date: 12-07-2007


Displaying 20 of 5,205 results for "SLC45A2"