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Displaying 17 of 17 results for "SLC39A3"
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  1. The conserved SUMO ligase Zip3 protein associates differentially with meiotic double-strand break sites and reveals regional variations in the outcome of mei... BioProject

    ID: PRJNA174310

    Keywords: Epigenomics

    Access Type: download

  2. The conserved SUMO ligase Zip3 protein associates differentially with meiotic double-strand break sites and reveals regional variations in the outcome of mei... OmicsDI

    ID: E-GEOD-40563

    Date Released: 06-02-2014

    Description: o, we have established the genome-wide map of the Zip3 protein binding sites in budding yeast meiosis. We show that Zip3 associates with DSB sites when these are engaged into repair by crossing over, and that Zip3 binding frequency at DSB reflects its tendency to be repaired as a crossover. We further show that the relative amount of Zip3 per DSB varies with the chromosomal location and identify chromosomal features associated with high or low Zip3 per DSB ratio. Among these is the negative regulation by proximity to a centromere and positive by the proximity to axis-asso...

  3. The conserved SUMO ligase Zip3 protein associates differentially with meiotic double-strand break sites and reveals regional variations in the outcome of mei... ArrayExpress

    ID: E-GEOD-40563

    Description: o, we have established the genome-wide map of the Zip3 protein binding sites in budding yeast meiosis. We show that Zip3 associates with DSB sites when these are engaged into repair by crossing over, and that Zip3 binding frequency at DSB reflects its tendency to be repaired as a crossover. We further show that the relative amount of Zip3 per DSB varies with the chromosomal location and identify chromosomal features associated with high or low Zip3 per DSB ratio. Among these is the negative regulation by proximity to a centromere and positive by the proximity to axis-asso...

  4. PGENETICS_TEL1_ReCombine_data Dryad

    DateIssued: 08-28-2015

    Description: ae. Genotypes analyzed are wild type, tel1, sgs1, zip3, msh4, tel1 zip3, and sgs1 zip3....

  5. Spo11-oligo mapping in zip3 mutants BioProject

    ID: PRJNA209592

    Keywords: Other

    Access Type: download

  6. S39A3_RAT UniProt:Swiss-Prot

    ID: Q5U1X7

    Description: Zinc transporter ZIP3 Extracellular Helical Cytoplasmic Helical Extracellular Helical Cytopla...

  7. S39A3_MOUSE UniProt:Swiss-Prot

    ID: Q99K24

    Description: Zinc transporter ZIP3 Extracellular Helical Cytoplasmic Helical Extracellular Helical Cytopla...

  8. S39A3_XENTR UniProt:Swiss-Prot

    ID: A4IIC5

    Description: Zinc transporter ZIP3 Extracellular Helical Cytoplasmic Helical Extracellular Helical Cytopla...

  9. Spo11-oligo mapping in zip3 mutants OmicsDI

    ID: E-GEOD-48299

    Date Released: 06-01-2014

    Description: dscape. Four samples total: two wild type and two zip3 mutant (each an independent culture)...

  10. Spo11-oligo mapping in zip3 mutants ArrayExpress

    ID: E-GEOD-48299

    Description: dscape. Four samples total: two wild type and two zip3 mutant (each an independent culture)...

  11. Data from: Reduced crossover interference and increased ZMM-independent recombination in the absence of Tel1/ATM Dryad

    DateIssued: 08-28-2015

    Description: ugh a pathway dependent on the ZMM proteins (Zip2-Zip3-Zip4-Spo16, Msh4-Msh5, Mer3), which form foci at CO-committed sites. Here we show that the DNA-damage-response kinase Tel1/ATM limits ZMM-independent recombination. By whole-genome mapping of recombination products, we find that lack of Tel1 results in higher recombination and reduced CO interference. Yet the number of Zip3 foci in tel1Δ cells is similar to wild type, and these foci show normal interfer...

  12. Simulation scripts Dryad

    DateIssued: 08-28-2015

    Description: Python scripts used to simulate crossover and DSB interference in Figure 6B.

    dataset.keywords: Zip3
  13. Numerical and Spatial Patterning of Yeast Meiotic DNA Breaks by Tel1 ArrayExpress

    ID: E-GEOD-84696

    Description: ibed contributions of the recombination regulator Zip3. Finally, we uncover a context-dependent role for Tel1 in hotspot competition, in which an artificial DSB hotspot inhibits nearby hotspots. Evidence for Tel1-dependent competition involving strong natural hotspots is also provided. Sixteen samples total: The first 12 are two biological replicate Spo11-oligo maps from each of the following: wild type and tel1 each collected at 4, 5, and 6 hours after meiotic induction; the next 4 are one biological replicate Spo11-oligo map from each of the following: wild type and tel1 bearing an artificial hotspot insertion either on Chr III or on Chr IX....

  14. Numerical and Spatial Patterning of Yeast Meiotic DNA Breaks by Tel1 OmicsDI

    ID: E-GEOD-84696

    Date Released: 07-22-2016

    Description: ibed contributions of the recombination regulator Zip3. Finally, we uncover a context-dependent role for Tel1 in hotspot competition, in which an artificial DSB hotspot inhibits nearby hotspots. Evidence for Tel1-dependent competition involving strong natural hotspots is also provided. Sixteen samples total: The first 12 are two biological replicate Spo11-oligo maps from each of the following: wild type and tel1 each collected at 4, 5, and 6 hours after meiotic induction; the next 4 are one biological replicate Spo11-oligo map from each of the following: wild type and tel1 bearing an artificial hotspot insertion either on Chr III or on Chr IX....

  15. Data from: Controlling meiotic recombinational repair: specifying the roles of ZMMs, Sgs1 and Mus81/Mms4 in crossover formation Dryad

    DateIssued: 10-27-2014

    Description: g over in distinct ways. Our results suggest that Zip3 (RNF212) promotes biased cutting of the double Holliday-junction (dHJ) intermediate whereas surprisingly Msh4 does not. Moreover, detailed examination of conversion tracts in sgs1 and mms4-md mutants reveal distinct aberrant recombination events involving multiple chromatid invasions. In sgs1 mutants, these multiple invasions are generally multichromatid involving 3–4 chromatids; in mms4-md mutants the multiple invasions preferentially resolve into one or two chromatids. Our analysis suggests that Mus81/Mms4 (Eme1), rather than just being a minor resolvase for COs is crucial for both COs and NCOs in prevent...

  16. Saccharomyces cerevisiae strain:S96 X YJM879 hybrid : Controlling Meiotic Recombinational Repair – Specifying the roles of ZMMs, Sgs1 and Mms4 in Cr... BioProject

    ID: PRJNA244749

    Keywords: genome sequencing

    Access Type: download

    dataset.description: synapsis promote crossing over in distinct ways. Zip3 (RNF212) promotes asymmetric cutting of the double Holliday-junction intermediate whereas Msh4 does not. Moreover, our analysis suggests that Mms4 (Eme1), rather than just being a minor resolvase for crossovers is crucial in preventing chromosome entanglements by removing 3’- flaps to promote second-end capture for both crossovers and noncrossovers. Recombination signature analysis opens a new window into the function of Holliday Junction-associated proteins....
  17. Numerical and Spatial Patterning of Yeast Meiotic DNA Breaks by Tel1 BioProject

    ID: PRJNA330852

    Keywords: Other

    Access Type: download

    dataset.description: ibed contributions of the recombination regulator Zip3. Finally, we uncover a context-dependent role for Tel1 in hotspot competition, in which an artificial DSB hotspot inhibits nearby hotspots. Evidence for Tel1-dependent competition involving strong natural hotspots is also provided. Overall design: Eighteen samples total: The first 14 are two biological replicate Spo11-oligo maps from each of the following: wild type and tel1 each collected at 4, 5, and 6 hours after meiotic induction; the next 4 are one biological replicate Spo11-oligo map from each of the following: wild type and tel1 bearing an artificial hotspot insertion either on Chr III or on Chr IX....

Displaying 17 of 17 results for "SLC39A3"