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  1. Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia BioProject

    ID: PRJNA169151

    Keywords: Epigenomics

    Access Type: download

    dataset.description: (NHLH1), and solute carrier family 16, member 7 (SLC16A7) in psychotic patients (p < 0.05, FDR q < 0.2). Additional expression and methylation datasets were used to validate the relationship between DNA methylation, gene expression, and neuropsychiatric diseases. These results suggest that the identiļ¬ed differentially expressed genes with an aberrant methylation pattern may represent novel candidate factors in the etiology and pathology of neuropsychiatric disorders. Overall design: A total of 155 postmortem cerebellum brains were used in this study, including 47 bipolar disorder, 46 schizophrenia, 15 depression patients and 47 normal controls. All were of European Ancestry. We also designed 13 random replicates in our experiment. Illumina Infinium HumanMethylation27 BeadChip was used for DNA methylation profiling. The assay was performed at the Genomics Core Facility at Northwestern University....

Displaying 1 of 1 results for "SLC16A7"