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Displaying 20 of 22 results for "SLC11A1"
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  1. Transcription profiling of liver from wild type and Hfe-/- mice with hereditary hemochromatosis subjected to dietary iron overload and treatment with ... ArrayExpress

    ID: E-MEXP-982

    Description: al iron overload are frequent clinical conditions associated with progressive iron accumulation in parenchymal tissues leading to eventual organ failure. We have discovered a novel mechanism to reverse iron overload by phar...

  2. Gene Expression profiles of colon from VhlF/F, VhlΔIE, VhlF/F/Apcmin/+, VhlΔIE/Apcmin/+ ArrayExpress

    ID: E-GEOD-36091

    Description: ruption of the von Hippel-Lindau tumor suppressor protein (VHL) resulted in constitutive HIF signaling, and increased HIF expression augmented colon tumorigenesis in the Apcmin/+ intestinal tumor model. Intestine-specific disruption of Vhl increased colon tumor multiplicity and progression from adenomas to carcinomas. These effects were ameliorated in mice with double disruption of Vhl and Hif-2α. Activation of HIF signaling resulted in increased cell survival in normal colon tissue, however tumor apoptosis was not affected. Interestingly, a robust activation of cyclin D1 was observed in tumors of Apcmin/+ mice in which HIF-2α was activated in the intestine. Consis...

  3. NRAM1_BISBI UniProt:Swiss-Prot

    ID: Q95102

    Description: Natural resistance-associated macrophage protein

  4. NRAM1_BOVIN UniProt:Swiss-Prot

    ID: Q27981

    Description: Natural resistance-associated macrophage protein

  5. NRAM1_BUBBU UniProt:Swiss-Prot

    ID: Q27946

    Description: Natural resistance-associated macrophage protein

  6. Slc11a1 alignment Dryad

    DateIssued: 02-24-2012

    Description: Sequence alignment files for each gene consist of individual field vole sequences and the consensus sequence uploaded to GenBank. SNPs are designated ...

  7. NRAM1_CHICK UniProt:Swiss-Prot

    ID: P51027

    Description: Natural resistance-associated macrophage protein

  8. NRAM1_CEREL UniProt:Swiss-Prot

    ID: P56436

    Description: Natural resistance-associated macrophage protein

  9. Gene Expression profiles of colon from VhlF/F, VhlΔIE, VhlF/F/Apcmin/+, VhlΔIE/Apcmin/+ BioProject

    ID: PRJNA151791

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ruption of the von Hippel-Lindau tumor suppressor protein (VHL) resulted in constitutive HIF signaling, and increased HIF expression augmented colon tumorigenesis in the Apcmin/+ intestinal tumor model. Intestine-specific disruption of Vhl increased colon tumor multiplicity and progression from adenomas to carcinomas. These effects were ameliorated in mice with double disruption of Vhl and Hif-2α. Activation of HIF signaling resulted in increased cell survival in normal colon tissue, however tumor apoptosis was not affected. Interestingly, a robust activation of cyclin D1 was observed in tumors of Apcmin/+ mice in which HIF-2α was activated in the intestine. Consis...
  10. qRT-PCR of ex vivo Salmonella enterica in NRAMP-1 minus/plus macrophage background BioProject

    ID: PRJNA135887

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. qRT-PCR of ex vivo Salmonella enterica in NRAMP-1 minus/plus macrophage background ArrayExpress

    ID: E-GEOD-26806

    Description: periment was to determine the impact of the NRAMP-1 (natural resistance-associated macrophage protein-1) on expression of Spi2 in S. enterica wild type (WT) an...

  12. Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1 (SeMet labeled) PDB

    ID: PDB:5F0M

    Description: Vacuolar protein sorting-associated protein 35, Vacuolar protein sorting-<

  13. Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1 PDB

    ID: PDB:5F0L

    Description: Vacuolar protein sorting-associated protein 35, Vacuolar protein sorting-<

  14. qRT-PCR of ex vivo Salmonella enterica in NRAMP-1 minus/plus macrophage background OmicsDI

    ID: E-GEOD-26806

    Date Released: 06-10-2014

    Description: periment was to determine the impact of the NRAMP-1 (natural resistance-associated macrophage protein-1) on expression of Spi2 in S. enterica wild type (WT) an...

  15. Crystal structure of Deinococcus radiodurans MntH, an Nramp-family transition metal transporter PDB

    ID: PDB:5KTE

    Description: Divalent metal cation transporter MntH, Fab Heavy Chain, Fab Light Chain

  16. Gene expression profiling of the effects of Cyclophosphamide on peripheral blood mononuclear cells ArrayExpress

    ID: E-GEOD-39324

    Description: lignancies. A single high-dose treatment quickly (1-2 days) induced an extensive transcriptional modulation in peripheral blood mononuclear cells, leading to the reduction of cell cycle and biosynthetic/metabolic processes and to the augmentation of transcripts related to DNA damage and cell death (p53 signaling pathway, CDKN1A, CCND3, BAX, BBC3, BID, DDB2, SESN2), of scavenger receptors involved in the recognition of death (MARCO, CD68, CD163L1, SCARB2), of antigen processing/presentation mediators (CIITA, CTSC, CTSL1, CTSZ, GLA, GAA, TPP1, NEU1, SLC11A1, LAMP-2), of T cell activation markers (CD6...

  17. Transcription profiling by high throughput sequencing of Arabidopsis crt1-1 mutant and in EIN2S645A-YFP-HA transgenic lines ArrayExpress

    ID: E-MTAB-4360

    Description: VE2 (EIN2), an NRAMP-homologous integral membrane protein, plays an essential role in ethylene signaling but its function remains enigmatic. Here we report that phosphorylation-regulated proteolytic processing of EIN2 triggers its endoplasmic reticulum (ER)-nucleus translocation, which is e...

  18. Single Cas9 nickase induced generation of NRAMP1 knockin cattle with reduced off-target effects BioProject

    ID: PRJNA319154

    Keywords: Epigenomics

    Access Type: download

    dataset.description: ding sites of catalytically inactive Cas9 (dCas9) protein in bovine fetal fibroblast cells (BFFs) in an unbiased manner. Overall design: In the present study, chromatin immunoprecipitation was performed on catalytically inactive double mutant (D10A and H840A) Cas9 (dCas9)(Mali et al. 2013a; Yang et a...
  19. Mycobacteria-induced anaemia: a molecular approach reveals the involvement of NRAMP1 and lipocalin-2 but not hepcidin ArrayExpress

    ID: E-GEOD-20024

    Description: ruloplasmin (Cp), hemopexin (Hpx), heme-oxygenase-1 (Hmox1) and lipocalin-2 (Lcn2). Both the anemia and the mRNA expression changes of iron-related genes are largely absent in C.D2 mice which bear a functional allele of the Nramp1 gene. These data suggest that anaemia due to a chronic infection with M. avium develops independently of elevated hepcidin expression and possibly involves ferroportin and/or lipocalin-2. A pool of five mice total RNAs for each condition was used in the experiments. Each two channel chip experiment was done in duplicates with swapped dyes....

  20. Gene expression profiling of the effects of Cyclophosphamide on peripheral blood mononuclear cells BioProject

    ID: PRJNA170604

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: lignancies. A single high-dose treatment quickly (1-2 days) induced an extensive transcriptional modulation in peripheral blood mononuclear cells, leading to the reduction of cell cycle and biosynthetic/metabolic processes and to the augmentation of transcripts related to DNA damage and cell death (p53 signaling pathway, CDKN1A, CCND3, BAX, BBC3, BID, DDB2, SESN2), of scavenger receptors involved in the recognition of death (MARCO, CD68, CD163L1, SCARB2), of antigen processing/presentation mediators (CIITA, CTSC, CTSL1, CTSZ, GLA, GAA, TPP1, NEU1, SLC11A1, LAMP-2), of T cell activation markers (CD6...

Displaying 20 of 22 results for "SLC11A1"