SIX2 | bioCADDIE Data Discovery Index
Mountain View
biomedical and healthCAre Data Discovery Index Ecosystem
help Advanced Search
Displaying 20 of 56 results for "SIX2"
i
  1. Genome-wide map of SIX2 and SIX1 binding in human embryonic kidney cortex BioProject

    ID: PRJNA298244

    Keywords: Epigenomics

    Access Type: download

  2. Genome-wide maps of Six2 and b-catenin in mesenchymal nephron progenitors BioProject

    ID: PRJNA172117

    Keywords: Epigenomics

    Access Type: download

  3. Gene expression profiling of Six2-positive nephron progenitors from mouse embryo BioProject

    ID: PRJNA314756

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. Homo sapiens, Mus musculus : Comparing SIX2 binding sites in human and mouse nephron progenitors BioProject

    ID: PRJNA298089

    Keywords: epigenomics

    Access Type: download

  5. Genome-wide maps of Six2 and b-catenin in mesenchymal nephron progenitors OmicsDI

    ID: E-GEOD-39837

    Date Released: 05-03-2014

    Description: wing undifferentiated nephron progenitors express Six2, a transcription factor that is required for their maintenance as undifferentiated progenitors. Differentiation of nephron progenitors ...

  6. Gene expression profiling of Six2-positive nephron progenitors from mouse embryo ArrayExpress

    ID: E-GEOD-79024

    Description: d state. To understand how expression profiles of Six2+ cells changed during culture in vitro compared with in vivo, we performed microarray analysis of Six2+ cells at E11.5 (starting material) and P0 (experiencing 8 days in vivo), and cultured Six2+ cells at E11.5 for 8 days or 19 days. Microarray analysis were performed with isolated Six2-positive nephron progenitors from transgenic mice embryo at ...

  7. Genome-wide maps of Six2 and b-catenin in mesenchymal nephron progenitors ArrayExpress

    ID: E-GEOD-39837

    Description: wing undifferentiated nephron progenitors express Six2, a transcription factor that is required for their maintenance as undifferentiated progenitors. Differentiation of nephron progenitors ...

  8. Mus musculus : Sall1 co-operates with Six2 to actively maintain nephron progenitors BioProject

    ID: PRJDB2749

    Keywords: Other

    Access Type: download

  9. Gene expression profiling of Six2-positive nephron progenitors from mouse embryo. OmicsDI

    ID: E-GEOD-79024

    Date Released: 05-24-2016

    Description: d state. To understand how expression profiles of Six2+ cells changed during culture in vitro compared with in vivo, we performed microarray analysis of Six2+ cells at E11.5 (starting material) and P0 (experiencing 8 days in vivo), and cultured Six2+ cells at E11.5 for 8 days or 19 days. Microarray analysis were performed with isolated Six2-positive nephron progenitors from transgenic mice embryo at ...

  10. Genome-wide maps of SIX1, SIX2, and active loci in human fetal kidneys generated from ChIP-seq data. BioProject

    ID: PRJNA305763

    Keywords: Epigenomics

    Access Type: download

  11. The homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression BioProject

    ID: PRJNA247776

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Transcriptional profiling of human and mouse nephron progenitor cells BioProject

    ID: PRJNA298246

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: , the related transcriptional regulators Six1 and Six2 play non-overlapping roles in nephron progenitors. Transient Six1 activity prefigures, and is essential for, active nephrogenesis. In contrast, Six2 maintains later progenitor self-renewal from the onset of nephrogenesis. We compared Six2’s ...
  13. Age-dependent gene expression changes in human islets BioProject

    ID: PRJNA248621

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ic profiling of Endo-ßH1C cells expressing SIX3, SIX2 or GFP. Overall design: Profiling FACS-purified human pancreatic islet cells by RNA-Seq. We analyzed the gene expression changes in Endo-ßH1C cells expressing SIX3, SIX2 or GFP using RNA-Seq....
  14. Dissecting stages of human kidney development and Tumorigenesis with surface markers affords simple prospective Purification of nephron stem cells ArrayExpress

    ID: E-GEOD-78502

    Description: morigenesis; In nephrogenesis, NCAM1+CD133- marks SIX2+ multipotent renal stem cells transiting to NCAM1+CD133+ differentiating segment-specific SIX2- epithelial progenitors and NCAM1-CD133+ differentiated nephron cells. In tumorigenesis, NCAM1+CD133- marks SIX2+ blastema that includes the ALDH1+ WT cancer stem/initiating cells, while NCAM1+CD133+ and NCAM1-CD133+ specifying early and late epithelial differentiation, are severely restricted in tumor initiation capacity and tumor self-renewal. Thus, negative selection for CD133 is required for defining NCAM1+ nephron stem cells in normal and malignant nephrogenesis. Human fetal kidney mRNA profiles of 3 cell populations (NCAM1+/CD133-, NCAM+/CD133+, NCAM-/CD133+) were generated by deep sequencing using ...

  15. Sall1 co-operated with Six2 to actively maintain nephron progenitors in the embryonic kidney ArrayExpress

    ID: E-GEOD-45845

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

  16. Gene expression profiles of E15.5 cap mesenchyme isolated from Six2 transgenic mice using FACS. (GUDMAP Series ID: 23) BioProject

    ID: PRJNA112835

    Keywords: Transcriptome or Gene expression

    Access Type: download

  17. Dissecting stages of human kidney development and Tumorigenesis with surface markers affords simple prospective Purification of nephron stem cells BioProject

    ID: PRJNA313148

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: morigenesis; In nephrogenesis, NCAM1+CD133- marks SIX2+ multipotent renal stem cells transiting to NCAM1+CD133+ differentiating segment-specific SIX2- epithelial progenitors and NCAM1-CD133+ differentiated nephron cells. In tumorigenesis, NCAM1+CD133- marks SIX2+ blastema that includes the ALDH1+ WT cancer stem/initiating cells, while NCAM1+CD133+ and NCAM1-CD133+ specifying early and late epithelial differentiation, are severely restricted in tumor initiation capacity and tumor self-renewal. Thus, negative selection for CD133 is required for defining NCAM1+ nephron stem cells in normal and malignant nephrogenesis. Overall design: Human fetal kidney mRNA profiles of 3 cell populations (NCAM1+/CD133-, NCAM+/CD133+, NCAM-/CD133+) were generated by deep s...
  18. Dissecting stages of human kidney development and Tumorigenesis with surface markers affords simple prospective Purification of nephron stem cells OmicsDI

    ID: E-GEOD-78502

    Date Released: 04-11-2016

    Description: morigenesis; In nephrogenesis, NCAM1+CD133- marks SIX2+ multipotent renal stem cells transiting to NCAM1+CD133+ differentiating segment-specific SIX2- epithelial progenitors and NCAM1-CD133+ differentiated nephron cells. In tumorigenesis, NCAM1+CD133- marks SIX2+ blastema that includes the ALDH1+ WT cancer stem/initiating cells, while NCAM1+CD133+ and NCAM1-CD133+ specifying early and late epithelial differentiation, are severely restricted in tumor initiation capacity and tumor self-renewal. Thus, negative selection for CD133 is required for defining NCAM1+ nephron stem cells in normal and malignant nephrogenesis. Human fetal kidney mRNA profiles of 3 cell populations (NCAM1+/CD133-, NCAM+/CD133+, NCAM-/CD133+) were generated by deep sequencing using ...

  19. The Wilms' tumor blastema propagating cell is a self-renewing committed epithelial stem cell ArrayExpress

    ID: E-GEOD-57269

    Description: enografts composed solely by cells expressing the SIX2 and NCAM1 embryonic renal stem cell markers, we surprisingly show that sorted ALDH1+ WT CSCs are phenotypically not the earliest renal stem cells. Rather, gene expression and proteomic comparative analysis disclose a more differentiated self-renewing epithelial cell type than bulk of the blastema. Thus, WT CSCs do not represent the transformed counterpart of the most primitive renal stem cell being more differentiated than the presumable WT cell of origin and are likely to de-differentiate to propagate the tumor blastema. We used Wilms tumor...

  20. Sall1 co-operated with Six2 to actively maintain nephron progenitors in the embryonic kidney OmicsDI

    ID: E-GEOD-45845

    Date Released: 06-03-2014

    Description: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series


Displaying 20 of 56 results for "SIX2"