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Displaying 20 of 109 results for "SIN3A"
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  1. Fam60a defines a embryonic stem cell specific Sin3a/Hdac complex. BioProject

    ID: PRJNA320432

    Keywords: Epigenomics

    Access Type: download

  2. Solution structure of Sds3 in complex with Sin3A PDB

    ID: PDB:2N2H

    Description: Sin3 histone deacetylase corepressor complex component SDS3, Paired amphipathic helix protein Sin3a

  3. The Sin3a/HDAC co-repressor complex cooperates with Nanog in promoting stem cell pluripotency and somatic cell reprogramming [Microarray Expression] BioProject

    ID: PRJNA356573

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. The Sin3a/HDAC co-repressor complex cooperates with Nanog in promoting stem cell pluripotency and somatic cell reprogramming [ChIP-Seq] BioProject

    ID: PRJNA356691

    Keywords: Epigenomics

    Access Type: download

  5. Genome-wide maps of Sin3A and Sin3B binding in C2C12 myoblasts and differentiated myotubes BioProject

    ID: PRJNA128453

    Keywords: Epigenomics

    Access Type: download

  6. The Sin3a/HDAC co-repressor complex cooperates with Nanog in promoting stem cell pluripotency and somatic cell reprogramming BioProject

    ID: PRJNA356688

    Access Type: download

  7. Murine Testes: Germ Cell-Specific Sin3a Knockout vs. Hemizygous vs. Wild Type at Postnatal Day 0 BioProject

    ID: PRJNA167202

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. SIN3A-regulated LIF-responsive genes in MCF7 cells BioProject

    ID: PRJNA152031

    Keywords: Transcriptome or Gene expression

    Access Type: download

  9. SIN3A-regulated LIF-responsive genes in MCF7 cells ArrayExpress

    ID: E-GEOD-35696

    Description: wing a genome-wide RNAi screen, we identified the Sin3a complex as an important mediator of this STAT3 transcriptional repression. Sin3a directly interacts with the DNA-binding domain of STAT3 and alters its acetylation status. SIN3A silencing enhances recruitment of STAT3 and enhanceosome components to the SOCS3 promoter, resulting in histone hyperacetylation and enhanced transcription. Conversely, Sin3a is required for ISGF3-dependent gene transcription and for an efficient IFN-mediated antiviral protection...

  10. Genome-wide maps of Sin3A and Sin3B binding in C2C12 myoblasts and differentiated myotubes ArrayExpress

    ID: E-GEOD-22554

    Description: Sin3A and Sin3B bind to distinct and overlapping target sites. Sin3 proteins bind to distinct sites in cycling myoblasts whereas th...

  11. Murine Testes: Germ Cell-Specific Sin3a Knockout vs. Hemizygous vs. Wild Type at Postnatal Day 0 OmicsDI

    ID: E-GEOD-38096

    Date Released: 10-18-2012

    Description: Chromatin modifier Swi-independent 3a (SIN3A), together with associated histone deacetylases, influences gene expression during development and differentiation through mu...

  12. SIN3A-regulated LIF-responsive genes in MCF7 cells OmicsDI

    ID: E-GEOD-35696

    Date Released: 08-17-2015

    Description: wing a genome-wide RNAi screen, we identified the Sin3a complex as an important mediator of this STAT3 transcriptional repression. Sin3a directly interacts with the DNA-binding domain of STAT3 and alters its acetylation status. SIN3A silencing enhances recruitment of STAT3 and enhanceosome components to the SOCS3 promoter, resulting in histone hyperacetylation and enhanced transcription. Conversely, Sin3a is required for ISGF3-dependent gene transcription and for an efficient IFN-mediated antiviral protection...

  13. Targeting the SIN3A-PF1 Interaction inhibits Epithelial to Mesenchymal Transition and Maintenance of a Stem Cell Phenotype in Triple Negative Bre... BioProject

    ID: PRJNA298252

    Access Type: download

  14. Murine Testes: Germ Cell-Specific Sin3a Knockout vs. Hemizygous vs. Wild Type at Postnatal Day 0 ArrayExpress

    ID: E-GEOD-38096

    Description: Chromatin modifier Swi-independent 3a (SIN3A), together with associated histone deacetylases, influences gene expression during development and differentiation through mu...

  15. Chip-chip from THP1 cells with H3K4me3, H3K9me2 , H3K27me3, JARIDIA, LSD1, JHDM1A, JHDM2A, JHDM3A, SIN3A, SNF2H, BRG1 BioProject

    ID: PRJNA187980

    Keywords: Epigenomics

    Access Type: download

  16. Epigenetic and transcriptional regulation of starvation-induced atrophy and autophagy programs by Foxk1 and Sin3A BioProject

    ID: PRJNA244979

    Keywords: Other

    Access Type: download

  17. NMR STRUCTURE OF THE HUMAN MAD1 TRANSREPRESSION DOMAIN SID IN COMPLEX WITH MAMMALIAN SIN3A PAH2 DOMAIN PDB

    ID: PDB:1G1E

    Description: MAD1 PROTEIN/SIN3A

  18. Tet1 and hydroxymethylcytosine in transcription and DNA methylation fidelity (ChIP/DIP-Seq data) ArrayExpress

    ID: E-GEOD-24841

    Description: l repression. We showed that Tet1 associates with Sin3A co-repressor complex, and by performing ChIP-sequencing of Sin3A, we find co-localisation of Tet1 and Sin3a throughout the genome Examination of Tet1 and Sin3A binding as well as hmC and mC localization in mouse ES cells...

  19. Chip-chip from THP1 cells with H3K4me3, H3K9me2 , H3K27me3, JARIDIA, LSD1, JHDM1A, JHDM2A, JHDM3A, SIN3A, SNF2H, BRG1 ArrayExpress

    ID: E-GEOD-43869

    Description: THP1 cells were ChIPed with indicated antibodies. Comparison of selected chromatin marks in THP1 cells

  20. Epigenetic and transcriptional regulation of starvation-induced atrophy and autophagy programs by Foxk1 and Sin3A ArrayExpress

    ID: E-GEOD-56932

    Description: targets in muscle. Foxk1/2 specifically recruits Sin3A-HDAC complexes to restrict acetylation of histone H4 and expression of critical autophagy genes. Remarkably, mTOR promotes the transcriptional activity of Foxk1 by facilitating nuclear entry to specifically limit basal levels of autophagy in nutrient-rich conditions. Our study highlights an ancient, conserved mechanism whereby nutritional status is interpreted by mTOR to restrict autophagy by repressing essential autophagy genes via Foxk-Sin3-mediated transcriptional control. Examination of (1) chromatin binding of Foxk1 and Sin3A in non-starved myoblasts and (2) gene expression profiling upon either starvation or siRNA-mediated depletion of Foxk1 relative to a non-starved control....


Displaying 20 of 109 results for "SIN3A"