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Displaying 9 of 9 results for "SEC16A"
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  1. MAG5_ARATH UniProt:Swiss-Prot

    ID: Q9FGK9

    Description: Protein transport protein SEC16A homolog Ser-rich Phosphoserine

  2. Patterns of microRNA Expression in Non-Human Primate ArrayExpress

    ID: E-GEOD-22920

    Description: gene expression post-transcriptionally. They play a critical role in developmental and physiological processes and have been implicated in the pathogenesis of several diseases including cancer. To identify miRNA signatures associated with different s...

  3. Deficiency in the 15 kDa Selenoprotein Inhibits Tumorigenicity and Metastasis of Colon Cancer Cells ArrayExpress

    ID: E-GEOD-20390

    Description: these observations, subsequent analyses revealed a G2/M cell cycle arrest in Sep15 CT26 knockdown cells. In contrast, to CT26 cells Sep15 knockdown in Lewis Lung Carcinoma (LLC1) cells did not affect anchorage-dependent or –independent cell growth. These data suggest tissue specificity in the cancer protective effects of Sep15 knockdown, which are mediated, at least in part, by influencing the cell cycle. mRNA was isolated from plasmid-transfected control and shSep15 knockdown CT26 cells (three replicates of each). Microarray analysis was performed on Affymetrix Mouse 430_2 gene chips. Three arrays were analyzed from different mRNA samples for each construct....

  4. Patterns of microRNA Expression in Non-Human Primate BioProject

    ID: PRJNA127979

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: gene expression post-transcriptionally. They play a critical role in developmental and physiological processes and have been implicated in the pathogenesis of several diseases including cancer. To identify miRNA signatures associated with different s...
  5. Deficiency in the 15 kDa Selenoprotein Inhibits Tumorigenicity and Metastasis of Colon Cancer Cells BioProject

    ID: PRJNA125515

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: resulting Sep15-deficient CT26 cells was reduced (p250 lung metastases/mouse; however, mice injected with the Sep15 knockdown cells only had 7.8 +/- 5.4 metastases. To investigate molecular targets affected by Sep15 status, gene expression patterns between control and knockdown CT26 cells were compared. Ingenuity Pathways Analysis was used to analyze the 1045 genes that were significantly (p<0.001) affected by Sep15 deficiency. The highest scored biological functions were cancer and cellular growth and proliferation. Consistent with these observations, subsequent analyses rev...
  6. Gene profile of breast cancers with immunohistochemical phenotypes of ER+/- and/or HER2+/- BioProject

    ID: PRJNA99585

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: cancers and ER(-)/HER2(-) cancers tended to form a tumor cluster, but HER2 positive breast cancers were split into different tumor clusters. Significant differential expression between IHC-ER(-)/HER2(-) and other tumors was defined as having an expression level at least 2-fold higher or 2-fold lower, and analyzed by multi-step two-way ANOVA. Genes overexpressed differently in IHC-ER(-)/HER2(-) breast cancers compared to other all three types were 8 genes (FABP7, GABRP, GAL, CXCL13, CDC42EP4, C2F, FOXM1, CSDA), and underexpressed genes were nine including ITGB5, KIAA0310, MAGED2, PRSS11, SORL1, TGFB3, KRT18, CPE, BCAS1. No gene was directly related to cell proliferation such as cyclins, cyclin-dependent kinase, p53, p16, and the pRb and p21 families. We had a particular focus on a transcriptional factor E2F-5 from a list of genes overexpressed in ER negative breast cancers...
  7. Gene profile of breast cancers with immunohistochemical phenotypes of ER+/- and/or HER2+/- GEMMA

    ID: 2649

    Keywords: functional genomics

    Description: cancers and ER(-)/HER2(-) cancers tended to form a tumor cluster, but HER2 positive breast cancers were split into different tumor clusters. Significant differential expression between IHC-ER(-)/HER2(-) and other tumors was defined as having an expression level at least 2-fold higher or 2-fold lower, and analyzed by multi-step two-way ANOVA. Genes overexpressed differently in IHC-ER(-)/HER2(-) breast cancers compared to other all three types were 8 genes (FABP7, GABRP, GAL, CXCL13, CDC42EP4, C2F, FOXM1, CSDA), and underexpressed genes were nine including ITGB5, KIAA0310, MAGED2, PRSS11, SORL1, TGFB3, KRT18, CPE, BCAS1. No gene was directly related to cell proliferation such as cyclins, cyclin-dependent kinase, p53, p16, and the pRb and p21 families. We had a particular focus on a transcriptional factor E2F-5 from a list of genes overexpressed in ER negative breast cancers...

  8. Patterns of microRNA Expression in Non-Human Primate OmicsDI

    ID: E-GEOD-22920

    Date Released: 05-01-2014

    Description: gene expression post-transcriptionally. They play a critical role in developmental and physiological processes and have been implicated in the pathogenesis of several diseases including cancer. To identify miRNA signatures associated with different s...

  9. 99 Metabolomics

    Study Name: Metabolomics in Sarcoidosis

    Grant ID: U01 DK097430-01

    dataRepository.description: The Metabolomics Workbench serves as a national and international repository for metabolomics data and metadata and provides analysis tools and access to metabolite sta...

Displaying 9 of 9 results for "SEC16A"