S100A7 | bioCADDIE Data Discovery Index
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Displaying 20 of 36 results for "S100A7"
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  1. STRUCTURE OF HUMAN S100A7 IN COMPLEX WITH 2,6 ANS PDB

    ID: PDB:2WOS

    Description: PROTEIN S100-A7

  2. STRUCTURE OF AN S100A7 TRIPLE MUTANT PDB

    ID: PDB:2WND

    Description: PROTEIN S100-A7

  3. CO-STRUCTURE OF S100A7 WITH 1,8 ANS PDB

    ID: PDB:2WOR

    Description: PROTEIN S100-A7

  4. S10A7_HORSE UniProt:Swiss-Prot

    ID: Q14ST5

    Description: Removed Protein S100-A7 EF-hand 1 EF-hand 2 2; high affinity Zinc Zinc Zinc Zinc N-acetylserine...

  5. Structure of human S100A7 D24G bound to zinc and calcium PDB

    ID: PDB:4AQJ

    Description: PROTEIN S100-A7

  6. Role of S100A7 in regulating inflammatory pathways during mammary tumorigenesis BioProject

    ID: PRJNA147669

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Role of S100A7 in regulating inflammatory pathways during mammary tumorigenesis OmicsDI

    ID: E-GEOD-32052

    Date Released: 11-14-2011

    Description: Psoriasin (S100A7) has been shown to be highly expressed in invasive estrogen receptor negative breast cancers. Expression of

  8. Role of S100A7 in regulating inflammatory pathways during mammary tumorigenesis ArrayExpress

    ID: E-GEOD-32052

    Description: Psoriasin (S100A7) has been shown to be highly expressed in invasive estrogen receptor negative breast cancers. Expression of

  9. HUMAN PSORIASIN (S100A7) PDB

    ID: PDB:1PSR

    Description: PSORIASIN, HOLMIUM ATOM

  10. HUMAN PSORIASIN (S100A7) CA2+ AND ZN2+ BOUND FORM (CRYSTAL FORM II) PDB

    ID: PDB:2PSR

    Description: PSORIASIN

  11. S1A7B_HUMAN UniProt:Swiss-Prot

    ID: Q5SY68

    Description: Protein S100-A7-like 2 EF-hand 1 EF-hand 2 2; high affinity Zinc Zinc

  12. HUMAN PSORIASIN (S100A7) CA2+ BOUND FORM (CRYSTAL FORM I) PDB

    ID: PDB:3PSR

    Description: PSORIASIN

  13. Transcription profiling by array of acute and chronic atopic dermatitis compared to normal skin ArrayExpress

    ID: E-GEOD-36842

    Description: iation proteins, specifically the IL-22-modulated S100A7-9. Correspondingly, acute disease is associated with significant increases in gene expression levels of the major Th22- (IL-22) and Th2- (IL-4, IL-31) cytokines and Th17-regulated genes (CCL20, PI3/Elafin), without significant changes in IL-17. A lesser induction of Th1- (IFNγ, MX-1, CXCL9-11) associated genes was detected in acute disease. Chronic skin lesions are characterized by significantly intensified activation of Th22, Th2 and Th1. Our data establish increased expression of S100A7-9 and other epidermal genes at onset of acute AD, with parallel activation of Th2 and Th22 cytokines. Our findings suggest an absence of switch mechanism in chronic disease and instead indicate that progression to chronic lesions is associated with intensified activation of immune axes that initiate onset of acute lesions, partic...

  14. The conjunctival transcriptome in scarring trachoma ArrayExpress

    ID: E-GEOD-23705

    Description: -inflammatory cytokine production (IL-1β, CXCL5, S100A7) and tissue remodelling (MMP7, MMP9, MMP12, HAS3). There was no difference in the level of IFNG between cases and controls. However, cases had increased INDO, NOS2A, and IL13RA2 and reduced IL13. Ct was detected in 1/772. Cases show evidence of ongoing inflammation and tissue remodelling, which were more marked where clinical inflammation was also present. Significantly, these processes appear to be active in the absence of current Ct infection. There was limited evidence of a TH1 response (INDO, NOS2A) and no association between a TH2 response and cases. The epithelium appears actively involved in late cicatricial stages of trachoma through production of pro-inflammatory factors (IL-1β, CXCL5, S100A7). Longitudinal studies are needed to investigate which aetiological factors and pathways are associated with progressive scarring and whether simply controlling chlamydial infection w...

  15. Identification of p130Cas/ErbB2 dependent invasive signatures in transformed mammary epithelial cells ArrayExpress

    ID: E-GEOD-43907

    Description: enes involved in the inflammatory response (SAA1, S100A7) are down-regulated. In parallel, we have shown that the expression of specific miRNAs is altered. Among these, mir-200b, miR-222, miR-221and miR-424 are up-regulated while miR-27a, miR-27b and miR-23b are down-regulated. Overall this study present, for the first time, gene expression changes underlying the invasive behaviour following p130Cas over-expression in an ErbB2 transformed mammary cell model. 12 samples were analyzed: 3 ErbB2, 3 Cas, 3 Cas/ErbB2, 3 Ctr MCF10A.B2...

  16. The conjunctival transcriptome in scarring trachoma BioProject

    ID: PRJNA130903

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: -inflammatory cytokine production (IL-1β, CXCL5, S100A7) and tissue remodelling (MMP7, MMP9, MMP12, HAS3). There was no difference in the level of IFNG between cases and controls. However, cases had increased INDO, NOS2A, and IL13RA2 and reduced IL13. Ct was detected in 1/772. Cases show evidence of ongoing inflammation and tissue remodelling, which were more marked where clinical inflammation was also present. Significantly, these processes appear to be active in the absence of current Ct infection. There was limited evidence of a TH1 response (INDO, NOS2A) and no association between a TH2 response and cases. The epithelium appears actively involved in late cicatricial stages of trachoma through production of pro-inflammatory factors (IL-1β, CXCL5, S100A7). Longitudinal studies are needed to investigate which aetiological factors and pathways are associated with progressive scarring and whether simply controlling chlamydial infection w...
  17. The conjunctival transcriptome in scarring trachoma OmicsDI

    ID: E-GEOD-23705

    Date Released: 08-16-2011

    Description: -inflammatory cytokine production (IL-1β, CXCL5, S100A7) and tissue remodelling (MMP7, MMP9, MMP12, HAS3). There was no difference in the level of IFNG between cases and controls. However, cases had increased INDO, NOS2A, and IL13RA2 and reduced IL13. Ct was detected in 1/772. Cases show evidence of ongoing inflammation and tissue remodelling, which were more marked where clinical inflammation was also present. Significantly, these processes appear to be active in the absence of current Ct infection. There was limited evidence of a TH1 response (INDO, NOS2A) and no association between a TH2 response and cases. The epithelium appears actively involved in late cicatricial stages of trachoma through production of pro-inflammatory factors (IL-1β, CXCL5, S100A7). Longitudinal studies are needed to investigate which aetiological factors and pathways are associated with progressive scarring and whether simply controlling chlamydial infection w...

  18. CEACAM6 is a PDEF induced gene in breast cancer BioProject

    ID: PRJNA162647

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: PDEF. Further analysis of 3 of these genes namely S100A7, CEACAM6 and B7-H4 in primary breast tumors showed CEACAM6 as a frequently elevated and co-exressed gene with PDEF in these tumors. We previously reported a role for PDEF (prostate derived Ets transcription factor) in breast tumor progression and its association with poor clinical outcome in ER+ breast cancer. To gain further insights into PDEF action in breast cancer, we down regulated PDEF expression by shRNA in MCF-7 human breast tumor cell line, and screened the HG-U133A human gene chips with probes from PDEF down-regulated and control MCF-7 cells. This analysis identified CEACAM6 as one of th...
  19. Transcription profiling of lesional and non-lesional skin from acne patients to study the role of inflammation in early acne lesions ArrayExpress

    ID: E-GEOD-53795

    Description: Foxp3, IL-10, TGF-β) and antimicrobial peptides (S100A7, S100A9, LNC2, hBD2, hBD3, hCAP18) were induced. Importantly, immunohistochemistry revealed significantly increased numbers of IL-17A positive T cells and CD83 dendritic cells in the acne lesions. In summary our results demonstrate the presence of IL17A positive T cells and the activation of Th17-related cytokines in acne lesions, indicating that the Th17 pathway may play a pivotal role in the disease process, offering new targets of therapy. Total of 24 chips. 12 patients : 2 biospies per patient: 1 lesional and 1 non lesional....

  20. IL-17A plays a central role in the expression of psoriasis signature genes through induction of IkappaB-zeta in keratinocytes ArrayExpress

    ID: E-GEOD-77719

    Description: te typical psoriasis genes exemplified by DEFB4A, S100A7, IL19 and CSF3, based on differences in the expression profiles of cells stimulated with 6 cytokines versus cells stimulated with only 5 cytokines lacking IL-17A. Furthermore a specific IL-17A-induced gene, NFKBIZ, which encodes IkappaB-zeta, a transcriptional regulator for NF-kappaB, was demonstrated to have a significant role for IL-17A-induced gene expression. Thus, we present novel in vitro data from normal human keratinocytes that would help elucidating the IL-17A-driven keratinocyte activation in psoriasis. Cytokine mixture-induced gene expression in primary normal human epidermal keratinocytes (NHEKs) was measured at 24 hours after exposure. NHEKs were exposed to the combination of selected six cytokines (IL-17A: 100 ng/ml, TNF-a: 10 ng/ml, IFN-g: 10 ng/ml, IL-17C: 100 ng/ml, IL-22: 100 ng/ml, IL-36g: 500 ng/ml) , or to the different combinations of five of the six cytokines (in total, 7 different treatments and one untreated control). No replicate experiments were conducted....


Displaying 20 of 36 results for "S100A7"