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Displaying 20 of 4,865 results for "RXFP2"
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  1. Solution NMR structure of the RXFP2 LDLa module PDB

    ID: PDB:2M96

    Description: Relaxin receptor 2

  2. Solution structure of human relaxin-3 PDB

    ID: PDB:2FHW

    Description: Relaxin 3 (Prorelaxin H3) (Insulin-like peptide INSL7) (Insulin

  3. Suppression of insulin like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development ArrayExpress

    ID: E-GEOD-25222

    Description: age of testicular descent is controlled by INSL3, insulin like3 hormone, produced in testicular Leydig cells. Deletion of Insl3 or its receptor, Rxfp2, in mice causes cryptorchidism. We produced Cre/loxP regulated shRNA transgenic mice targeting RXFP2 expression. We have shown that the transgene was able to reduce Rxfp2 gene expression and thus behaved as a hypomo...

  4. Suppression of insulin like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development OmicsDI

    ID: E-GEOD-25222

    Date Released: 06-10-2011

    Description: age of testicular descent is controlled by INSL3, insulin like3 hormone, produced in testicular Leydig cells. Deletion of Insl3 or its receptor, Rxfp2, in mice causes cryptorchidism. We produced Cre/loxP regulated shRNA transgenic mice targeting RXFP2 expression. We have shown that the transgene was able to reduce Rxfp2 gene expression and thus behaved as a hypomo...

  5. Suppression of insulin like3 receptor reveals the role of β-catenin and Notch signaling in gubernaculum development BioProject

    ID: PRJNA134459

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Data from: Whole-genome resequencing uncovers molecular signatures of natural and sexual selection in wild bighorn sheep Dryad

    DateIssued: 03-08-2016

    Description: ctive sweep shared across multiple populations at RXFP2, a gene that strongly affects horn size in domestic ungulates. The massive horns carried by bighorn rams appear to have evolved in part via strong positive selection at RXFP2. We identified evidence for selection within individual populations at genes affecting early body growth and cellular response to hypoxia; however, these must be interpreted more cautiously as genetic drift is strong within local populations and may have caused false positives. These results represent a rare example of strong genomic signatures of selection identified at genes with known function in wild populations of a nonmodel species. Our results also showcase the value of reference genome assemblies from agricultural or model species for studies of the genomic basis of adaptation in closely related wild taxa....

  7. Expression data from bovine ovarian theca cells in primary culture ArrayExpress

    ID: E-GEOD-44704

    Description: njamini-Hochberg correction. BMP6 significantly (>2-fold; P<0.01) up- or down-regulated expression of 445 genes. Insulin-like peptide 3 (INSL3) was the most heavily down-regulated gene (-43-fold) with CYP17A1 and other key transcripts involved in TC steroidogenesis including LHCGR, INHA, STAR, CYP11A1 and HSD3B1 also down-regulated. BMP6 also reduced expression of NR5A1 encoding steroidogenic factor-1 known to target the promoter regions of the aforementioned genes. Real-time PCR confirmed these findings and also revealed a marked reduction in expression of INSL3 receptor (RXFP2). Secretion of INSL3 p...

  8. UPPS_MICLU UniProt:Swiss-Prot

    ID: O82827

    Description: Substrate Substrate Substrate Substrate Substrate Great decrease in activity Great decrease in activity. Decrease in activity; when associated with G-42 Decrease in affinity for decaprenyl diphosphate substrate analog Great decrease in activity. Decrease in activity; when associated with R-32 Decrease in activity; reduced affinity ...

  9. HUTP_BACSU UniProt:Swiss-Prot

    ID: P10943

    Description: Removed Hut operon positive regulatory protein Great decrease in binding affinity for mRNA Great decrease in binding affinity for mRNA Decrease in binding affi...

  10. Expression data from bovine ovarian theca cells in primary culture BioProject

    ID: PRJNA191062

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: njamini-Hochberg correction. BMP6 significantly (>2-fold; P<0.01) up- or down-regulated expression of 445 genes. Insulin-like peptide 3 (INSL3) was the most heavily down-regulated gene (-43-fold) with CYP17A1 and other key transcripts involved in TC steroidogenesis including LHCGR, INHA, STAR, CYP11A1 and HSD3B1 also down-regulated. BMP6 also reduced expression of NR5A1 encoding steroidogenic factor-1 known to target the promoter regions of the aforementioned genes. Real-time PCR confirmed these findings and also revealed a marked reduction in expression of INSL3 receptor (RXFP2). Secretion of INSL3 p...
  11. freshwater metagenome : Freshwater lentic microbial communities from great Laurentian Lakes, MI, USA - Great Lakes metaG MI27MSRF metagenome BioProject

    ID: PRJNA365766

    Keywords: metagenome

    Access Type: download

  12. freshwater metagenome : Freshwater lentic microbial communities from great Laurentian Lakes, MI, USA - Great Lakes metaG ER78MSRF metagenome BioProject

    ID: PRJNA365764

    Keywords: metagenome

    Access Type: download

  13. freshwater metagenome : Freshwater lentic microbial communities from great Laurentian Lakes, MI, USA - Great Lakes metaG HU45MSRF metagenome BioProject

    ID: PRJNA365765

    Keywords: metagenome

    Access Type: download

  14. freshwater metagenome : Freshwater lentic microbial communities from great Laurentian Lakes, MI, USA - Great Lakes metaG ER15MSRF metagenome BioProject

    ID: PRJNA365763

    Keywords: metagenome

    Access Type: download

  15. THE ARG7LYS MUTANT OF HEAT-LABILE ENTEROTOXIN EXHIBITS GREAT FLEXIBILITY OF ACTIVE SITE LOOP 47-56 OF THE A SUBUNIT PDB

    ID: PDB:1LTG

    Description: HEAT-LABILE ENTEROTOXIN

  16. freshwater metagenome : Freshwater lentic microbial communities from great Laurentian Lakes, MI, USA - Great Lakes metaG SU08MSRF metagenome BioProject

    ID: PRJNA365768

    Keywords: metagenome

    Access Type: download

  17. Male great apes : Great-ape Y-chromosome diversity BioProject

    ID: PRJEB12247

    Keywords: Other

    Access Type: download

  18. freshwater metagenome : Freshwater lentic microbial communities from great Laurentian Lakes, MI, USA - Great Lakes metaG ON33MSRF metagenome BioProject

    ID: PRJNA365767

    Keywords: metagenome

    Access Type: download

  19. Genotyping of 22 Great Danes with Ichthyosis BioProject

    ID: PRJNA296892

    Keywords: Epigenomics

    Access Type: download

  20. The transcriptome of Lymnaea stagnalis, the great pond snail BioProject

    ID: PRJEB7773

    Keywords: Other

    Access Type: download


Displaying 20 of 4,865 results for "RXFP2"