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Displaying 15 of 15 results for "RBM44"
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  1. RBM44_RAT UniProt:Swiss-Prot

    ID: D3Z987

    Description: RNA-binding protein 44 RRM Phosphoserine Phosphoserine Phosphoserine Phosp...

  2. RBM44_BOVIN UniProt:Swiss-Prot

    ID: E1BC15

    Description: RNA-binding protein 44 RRM Phosphoserine Phosphoserine Phosphoserine Phosp...

  3. Global Analysis of Glucocorticoid Receptor-Associated Transcripts and Identification of a Target RNA Motif BioProject

    ID: PRJNA132147

    Keywords: Other

    Access Type: download

  4. Global Analysis of Glucocorticoid Receptor-Associated Transcripts and Identification of a Target RNA Motif ArrayExpress

    ID: E-GEOD-24748

    Description: e of the human glucocorticoid receptor (GR) as an RNA-binding protein and its effect on mRNA turnover in human airway epithelial cells. Cell treatment with the potent GC budesonide accelerated the decay of CCL2 mRNA (t1/2=8±1 min vs. 62±17 min in DMSO-treated cells) and C...

  5. Global Analysis of Glucocorticoid Receptor-Associated Transcripts and Identification of a Target RNA Motif OmicsDI

    ID: E-GEOD-24748

    Date Released: 03-27-2012

    Description: e of the human glucocorticoid receptor (GR) as an RNA-binding protein and its effect on mRNA turnover in human airway epithelial cells. Cell treatment with the potent GC budesonide accelerated the decay of CCL2 mRNA (t1/2=8±1 min vs. 62±17 min in DMSO-treated cells) and C...

  6. shRNA knockdown of the transcription factor NF-YA (NFYA) ArrayExpress

    ID: E-GEOD-40215

    Description: ence-specific subunit (NF-YA), binds to the CCAAT motif, a common promoter element. Genome-wide mapping reveals 5,000-15,000 NF-Y binding sites depending on the cell type, with the NF-YA and NF-YB subunits binding asymmetrically with respect to the CCAAT

  7. Transcription profiling of human colon biopsy samples from healthy individuals and patients with colon adenomas, colorectal cancer or inflammatory bow... ArrayExpress

    ID: E-GEOD-4183

    Description: chemokine ligand-12, ADAM-like decysin-1 and ATP-binding casette A8 discriminatory genes. In IBD samples significantly increased lipocalin-2, interferon induced transmembrane protein 1 and 3 mRNA levels, decreased zinc finger protein 91 and transient receptor potential cation channel M6 mRNA levels were found. Ulcerative colitis and Crohn’s disease can be distinguished according to the top five genes: cyclin-G2; tripartite motif-containing-31; TNFR shedding aminopeptidase regulator-1; C-type lectin superfamily member-14 and AMICA. 88.3-97.8% of the cases was correctly classified according to discriminatory genes. Conclusions: Our whole genomic microarray analysis of biopsy samples provides discriminative signatures, and an insight into pathophysiological background of colonic disea...

  8. Transcription profiling of human LNCaP cell line ArrayExpress

    ID: E-GEOD-7868

    Description: ostate cancer. Surprisingly little is known of AR binding sites and collaborating transcription factors in the human genome. Here we have identified the DNA sequence motifs that are significantly enriched within the authentic 90 AR target regions found on chromosomes 21 and 22 in human prostate cancer ...

  9. Gene expression data from Wilms tumor samples ArrayExpress

    ID: E-GEOD-53224

    Description: DGCR8 exhibits stereotypic E518K mutations in the RNA binding domain - both may skew miRNA representation. SIX1 and SIX2 mutations affect a single hotspot (Q177R) in the homeodomain indicative of a dominant effect. In larger cohorts, these mutations cluster in blastemal and chemotherapy-induced regressive tumors that likely derive from blastemal cells and these are characterized by generally higher SIX1/2 expression. These findings broaden the spectrum of human cancer genes and may open new avenues for stratification and therapeutic leads for Wilms tumors. 53 Wilms tumor samples were selected for RNA extraction and hybridization on Affymetrix Affymetrix Human Genome U133 Plus 2.0 A...

  10. Control of Somatic Tissue Differentiation by the Long Non-Coding RNA TINCR (array) ArrayExpress

    ID: E-GEOD-40122

    Description: granules and intact lamellar bodies. Genome-scale RNA interactome analysis revealed that TINCR interacts with a suite of differentiation mRNAs. TINCR-mRNA interaction occurs through a 25 nucleotide “TINCR box” motif which is strongly enriched in interacting mRNAs \and required for TINCR binding. A high-throughput screen to analyze TINCR binding capacity to ~9,400 human recombinant proteins revealed direct binding of TINCR RNA to the Staufen1 (STAU1) protein. STAU1-deficient tissue recapitulated the impaired differentiation seen with TINCR depletion. Loss of UPF1 and UPF2, both of which are required for STAU1-mediated RNA decay (SMD), however, lacked differentiation impacts. Instead,...

  11. ZNF750 Drives Terminal Epidermal Differentiation via Induction of Klf4 ArrayExpress

    ID: E-GEOD-32685

    Description: , we defined a requirement for the ZNF750 nuclear protein in terminal epidermal differentiation. ZNF750 controlled genes mutated in numerous human skin diseases, including FLG, LOR, LCE3B, ALOXE3, and SPINK5. ZNF750 potently induced progenitor differentiation via an evolutionarily conserved C2H2 zinc finger motif. The epidermal mas...

  12. GAG_HV1H2 UniProt:Swiss-Prot

    ID: P04591

    Description: Removed; by host Gag polyprotein Matrix protein p17 Capsid protein p24 Spacer peptide 1 Nucleocapsid protein p7 Spacer peptide 2 p6-g...

  13. Transcription profiling of human monocytes after treatment vehicle, isotype control antibody, TREM1 antibody, LPS, isotype control antibody plus LPS a... ArrayExpress

    ID: E-GEOD-9988

    Description: REM-1 associates with and signals via the adapter protein DAP12/TYROBP, which contains an immunoreceptor tyrosine-based activation motif (ITAM). TREM-1 activation by receptor cross-linking is pro-inflammatory, and can amplify cellular responses to Toll...

  14. VIF_HV1N5 UniProt:Swiss-Prot

    ID: P12504

    Description: 3G; FG-box Interaction with host APOBEC3F; F2-box RNA-binding Multimerization Membrane association HCCH motif BC-box-like motif Cleavage in virion (by viral protease) Phosphothreonine; by host MAP4K1 Phosphoserine; by host Phosphoserine; by host MAP4K1 Phosphothreonine; by host In strain: Clinical isolate; from an asymptomati...

  15. Transcripts expression of Infliximab therapy for patients with Kawasaki disease ArrayExpress

    ID: E-GEOD-48498

    Description: These transcripts abundance in IFX had Nucleotide-binding oligomerization domain pathway that play a role in activation of NFκB and IL-1 signaling pathway outside the field of TNF-α signaling pathway. Fifty transcripts including Peptidase inhibitor-3 (PI3), Matrix metalloproteinase-8 (MMP8), Chemokine (C-C motif) receptor-2 (CCR2) and Pentraxin-3 (PTX3) were significantly down-regulated in IFX. Conclusion: We demonstrated that the inhibition of TNF-α by IFX have affected various molecular mechanism materially for IVIG-resistant KD patients. 28 samples of pre- and post-treatment in IFX-responsive patients (n=8) and IVIG-responsive patients (n=6)....


Displaying 15 of 15 results for "RBM44"