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Displaying 18 of 18 results for "RASD2"
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  1. The Crystal Structure of Tumor Endothelial Marker 8 (TEM8) extracellular domain PDB

    ID: PDB:3N2N

    Description: Anthrax toxin receptor 1

  2. Prospective gene expression analysis of human RNA samples from Hepatocellular Carcinoma in relation with growth rate and survival ArrayExpress

    ID: E-GEOD-54236

    Description: C samples that correlates with growth rate of the tumor and survival. This signature could eventually be used as prognostic marker. The samples were prospectively derived from hepatocellular carcinoma tissue as well as non-tumor tissue from the livers of the ...

  3. Prospective gene expression analysis of human RNA samples from Hepatocellular Carcinoma in relation with growth rate and survival BioProject

    ID: PRJNA236016

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: C samples that correlates with growth rate of the tumor and survival. This signature could eventually be used as prognostic marker. The samples were prospectively derived from hepatocellular carcinoma tissue as well as non-tumor tissue from the livers of the ...
  4. Transcription profiling of human PC-3-derived cell lines after transendothelial migration in vitro OmicsDI

    ID: E-GEOD-14405

    Date Released: 05-01-2014

    Description: subpopulation of cells, TEM4-18, that crossed an endothelial barrier more efficiently, but surprisingly, were less invasive than parental PC-3 cells in other contexts in vitro. Importantly, TEM4-18 cells were more aggressive than PC-3 cells in a murine metastatic colonization model. Microarray and FACS analysis of these cells showed that the expression of many genes previously associated with leukocyte trafficking and cancer cell extravasation were either unchanged or down-regulated. TE...

  5. Pituitary tumors contain a (CD31¯/CD45¯ purified) side population with 'tumor stem cell'-associated characteristics [set 2] BioProject

    ID: PRJNA266101

    Keywords: Transcriptome or Gene expression

    Access Type: download

  6. Transcription profiling of human PC-3-derived cell lines after transendothelial migration in vitro ArrayExpress

    ID: E-GEOD-14405

    Description: subpopulation of cells, TEM4-18, that crossed an endothelial barrier more efficiently, but surprisingly, were less invasive than parental PC-3 cells in other contexts in vitro. Importantly, TEM4-18 cells were more aggressive than PC-3 cells in a murine metastatic colonization model. Microarray and FACS analysis of these cells showed that the expression of many genes previously associated with leukocyte trafficking and cancer cell extravasation were either unchanged or down-regulated. TE...

  7. Fibrocyte-like cells mediate acquired resistance to anti-angiogenic therapy with bevacizumab BioProject

    ID: PRJNA255405

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: effect in cancer patients by inhibiting vascular endothelial growth factor (VEGF). However, its use is still limited due to the resistance to the initial response. Such resistance could be regulated by various cell typ...
  8. Pituitary tumors contain a (CD31¯/CD45¯ purified) side population with 'tumor stem cell'-associated characteristics [set 2] ArrayExpress

    ID: E-GEOD-62870

    Description: ch is known about mechanisms underlying pituitary tumor pathogenesis. We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor stem ce...

  9. Gene expression profiles of Wnt-1 overexpressing melanoma ArrayExpress

    ID: E-GEOD-26656

    Description: factors, the amount of VEGF-C was the single best marker to correlate with the amount of lymph-angiogenesis. mRNA expression array of human melanoma orthotopically grown in SCID mice. Comparison includes mRNA expression profile of two melanoma cell-lines (A375 and M24met) stably overexpressing control vector or Wnt-1 treated with or without CsA. Comparison #1 comprised Wnt-1 versus control in A375 and M24met melanoma, respectively. Comparison #2 comprised Wnt-1 + Cyclosporine A (CsA) versus Wnt-1 without CsA....

  10. Pituitary tumors contain a (CD31¯/CD45¯ purified) side population with 'tumor stem cell'-associated characteristics [set 2] OmicsDI

    ID: E-GEOD-62870

    Date Released: 08-19-2015

    Description: ch is known about mechanisms underlying pituitary tumor pathogenesis. We searched for a side population (SP) in pituitary tumor, representing cells with high efflux capacity and potentially enriching for cancer/tumor stem ce...

  11. Gene expression profiles of Wnt-1 overexpressing melanoma BioProject

    ID: PRJNA136395

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: factors, the amount of VEGF-C was the single best marker to correlate with the amount of lymph-angiogenesis. Overall design: mRNA expression array of human melanoma orthotopically grown in SCID mice. Comparison includes mRNA expression profile of two melanoma cell-lines (A375 and M24met) stably overexpressing control vector or Wnt-1 treated with or without CsA. Comparison #1 comprised Wnt-1 versus control in A375 and M24met melanoma, respectively. Comparison #2 comprised Wnt-1 + Cyclosporine A (CsA) versus Wnt-1 without CsA....
  12. Circulating endothelial cells in patients with chronic lymphocytic leukemia: clinical and biological characterization BioProject

    ID: PRJNA112133

    Keywords: Transcriptome or Gene expression

    Access Type: download

  13. Integrated Network and Microarray Analysis to Identify New Biomarkers in Ischemic Heart Disease BioProject

    ID: PRJNA105803

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: analysis alone. These three biomarkers, Vascular Endothelial Growth Factor B, thrombospondin-1 and placental growth factor are all related to angiogenesis, a natural process that favors the revascularization of the heart after MI and prevents the occurrence of HF. Therefore, combined network and microarray analysis allows a systematic and less biased approach to biomarker discovery. Overall design: The 32 patients of this study were divided in 2 groups corresponding to the extreme quartiles of FE values. The first group are the patients with low Ejection fraction and the second group are the patients with high ejection fraction. Blood ...
  14. Expression profile of PC-3-derived cell lines after transendothelial migration BioProject

    ID: PRJNA111795

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: subpopulation of cells, TEM4-18, that crossed an endothelial barrier more efficiently, but surprisingly, were less invasive than parental PC-3 cells in other contexts in vitro. Importantly, TEM4-18 cells were more aggressive than PC-3 cells in a murine metastatic colonization model. Microarray and FACS analysis of these cells showed that the expression of many genes previously associated with leukocyte trafficking and cancer cell extravasation were either unchanged or down-regulated. TE...
  15. Engineering endochondral ossification using Sonic Hedgehog for bone regeneration ArrayExpress

    ID: E-GEOD-22293

    Description: ls and prevascularized using human umbilical vein endothelial cells. We show that Shh induced, in vitro, the maturation of the engineered vascular network along with the expression of collagen type X which resulted, in vivo, in an improved vascularization and the rapid formation of large amounts of osteoids through EO. Osteoids further matured into, currently unmatched, clinically relevant amount of lamellar bone including osteoclasts, bone lining cells and bone marrow-like cavities. This result suggests that Hh is a master regulator of EO allowing for the formation of complex tissues with considerable therapeutic potential for bone regeneration. The effect of Cyclopamine on expression of Hedgehog, angiogenesis and axon guidance marker genes was analyzed by seeding a coculture of 92% hMSCs and ...

  16. Cancer genomics identifies regulatory gene networks associated with the transition from dysplasia to adenocarcinomas BioProject

    ID: PRJNA111245

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: use of laser microdissection we harvested either tumor or transgenic and non-transgenic but otherwise morphologically unaltered cells. We then searched genome wide for regulated genes and validated results by quantitative real-time PCR. Overall, 473 and 541 genes were significantly regulated when cancer versus transgenic and cancer versus non-transgenic cells were compared. Principal component analysis and hierarchical clustering of the data clearly separated the cancer cells from transgenic and non-transgenics and we observed predominately repression...
  17. Primate blood signs of arenavirus hemorrhagic fever BioProject

    ID: PRJNA97149

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: fy genes with altered expression after infection, 2) identify genes that could discriminate between a virulent and non-virulent infection, and 3) identify genes encoding products that could serve as treatment targets for FDA-approved pharmaceuticals. Genes related to all three of these categories have been identified and some have been given preliminary validation by quantitative PCR and proteomic studies. These genes will be valuable candidates for future validation as prognostic biomarkers We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. Keywords: time course Overall design: Rhesus macaqu...
  18. Transcription profiling of primate blood for signs of arenavirus hemorrhagic fever ArrayExpress

    ID: E-GEOD-5790

    Description: fy genes with altered expression after infection, 2) identify genes that could discriminate between a virulent and non-virulent infection, and 3) identify genes encoding products that could serve as treatment targets for FDA-approved pharmaceuticals. Genes related to all three of these categories have been identified and some have been given preliminary validation by quantitative PCR and proteomic studies. These genes will be valuable candidates for future validation as prognostic biomarkers; We used microarrays to detail the global programme of gene expression underlying cellularisation and identified distinct classes of up-regulated genes during this process. Experiment Overall Design: Rhesus macaques inocula...


Displaying 18 of 18 results for "RASD2"