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Displaying 20 of 4,765 results for "RASA1"
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  1. Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution PDB

    ID: PDB:4FSS

    Description: Ras GTPase-activating protein 1

  2. Solution structure of the SH3 domain of human Ras GTPase-activating protein 1 PDB

    ID: PDB:2GQI

    Description: Ras GTPase-activating protein 1

  3. NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1 PDB

    ID: PDB:2M51

    Description: Ras GTPase-activating protein 1

  4. Solution structure of the second SH2 domain of human Ras GTPase-activating protein 1 PDB

    ID: PDB:2GSB

    Description: Ras GTPase-activating protein 1

  5. RAS-GTPASE-ACTIVATING DOMAIN OF HUMAN P120GAP PDB

    ID: PDB:1WER

    Description: P120GAP

  6. RAS-RASGAP COMPLEX PDB

    ID: PDB:1WQ1

    Description: H-RAS, P120GAP, GUANOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE

  7. Crystal Structure of the Shark TBC1D15 GAP Domain PDB

    ID: PDB:5TUB

    Description: Shark TBC1D15 GTPase-activating Protein

  8. p190A GAP domain complex with RhoA PDB

    ID: PDB:5IRC

    Description: Rho GTPase-activating protein 35, Transforming protein RhoA

  9. Limitations of Relative Apparent Synapomorphy Analysis (RASA) for measuring phylogenetic signal. Dryad

    DateIssued: 10-06-2010

  10. PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies [ChIP-seq] ArrayExpress

    ID: E-GEOD-62499

    Description: cooperating with mutations in NF1. NF1 encodes a Ras GTPase-activating protein (RasGAP) and its loss drives cancer by activating Ras4. We show that SUZ12 loss potentiates the effects of NF1 mutations by amplifying Ras-driven transcription through effects on chromatin. Importantly, however, SUZ12 inactivation also triggers an epigenetic switch that sensitizes these cancers to bromodomain inhib- itors. Collectively, these studies not only reveal an unexpected con- nection between the PRC2 complex, NF1 and Ras, but also identify a promising e...

  11. Transcription profiling by array of human malignant peripheral nerve sheath tumour (MPNST) cell line 90-8TL with re-expressed SUZ12 or treated with br... ArrayExpress

    ID: E-GEOD-62500

    Description: cooperating with mutations in NF1. NF1 encodes a Ras GTPase-activating protein (RasGAP) and its loss drives cancer by activating Ras4. We show that SUZ12 loss potentiates the effects of NF1 mutations by amplifying Ras-driven transcription through effects on chromatin. Importantly, however, SUZ12 inactivation also triggers an epigenetic switch that sensitizes these cancers to bromodomain inhib- itors. Collectively, these studies not only reveal an unexpected con- nection between the PRC2 complex, NF1 and Ras, but also identify a promising epi...

  12. Crystal Structure of the C2-GAP Fragment of synGAP PDB

    ID: PDB:3BXJ

    Description: Ras GTPase-activating protein SynGAP

  13. Crystal structure of RhoA.GDP.MgF3 in complex with GAP domain of ArhGAP20 PDB

    ID: PDB:3MSX

    Description: Transforming protein RhoA (E.C.3.6.5.2), Rho GTPase-activating protein 20

  14. Crystal structure of the RasGAP C-terminal (RGC) domain of IQGAP2 PDB

    ID: PDB:3IEZ

    Description: Ras GTPase-activating-like protein IQGAP2

  15. Structure of the Rap-RapGAP complex PDB

    ID: PDB:3BRW

    Description: Rap1 GTPase-activating protein 1, Ras-related

  16. miR-132 mediates renal fibrosis: miRNA profiling of foxd1-derivative interstital cells derived from murine fibrotic kidneys compared to healthy kidney... BioProject

    ID: PRJNA307701

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: well as increased (p-)RB1, Cyclin-A and decreased RASA1, p21 levels in kidney lysates. Taken together, silencing miR-132 counteracts the progression of renal fibrosis by selectively decreasing myofibroblast proliferation and could potentially serve as a novel antifibrotic therapy. Overall design: Total RNA obtained from FACS sorted mouse FoxD1-derivative interstitial cells from healthy or fibrotic kidneys...
  17. Crystal structure of the RhoGAP domain of RICS PDB

    ID: PDB:3IUG

    Description: Rho/Cdc42/Rac GTPase-activating protein RICS

  18. Crystal structure of Ran-GPPNHP-RanBP1-RanGAP complex PDB

    ID: PDB:1K5D

    Description: GTP-binding nuclear protein RAN/Ran-specific GTPase-activating protein/Ran GTPase

  19. THE CRYSTAL STRUCTURE OF RNA1P: A NEW FOLD FOR A GTPASE-ACTIVATING PROTEIN PDB

    ID: PDB:1YRG

    Description: GTPASE-ACTIVATING PROTEIN RNA1_SCHPO

  20. miR-132 mediates renal fibrosis: Genome-wide analysis of gene expression in foxd1-derivative interstital cells derived from fibrotic kidneys from mice... BioProject

    ID: PRJNA307700

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: well as increased (p-)RB1, Cyclin-A and decreased RASA1, p21 levels in kidney lysates. Taken together, silencing miR-132 counteracts the progression of renal fibrosis by selectively decreasing myofibroblast proliferation and could potentially serve as a novel antifibrotic therapy. Overall design: Total RNA obtained from FACS sorted mouse renal FoxD1-derivatve interstitial cells from mice that were treated with antagomir-132 or scramblemir and underwent UUO (n=4)...

Displaying 20 of 4,765 results for "RASA1"