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Displaying 13 of 13 results for "RAB4A"
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  1. Activation of mTOR controls the loss of TCRζ in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation BioProject

    ID: PRJNA110359

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. HIGH RESOLUTION STRUCTURE OF GPPNHP-BOUND HUMAN RAB4A PDB

    ID: PDB:2BME

    Description: RAS-RELATED PROTEIN RAB4A (E.C.3.6.5.2)

  3. HIGH RESOLUTION STRUCTURE OF GDP-BOUND HUMAN RAB4A PDB

    ID: PDB:2BMD

    Description: RAS-RELATED PROTEIN RAB4A (E.C.3.6.5.2)

  4. Transcription profiling by array of human CD3-positive T cells from patients with systemic lupus erythematosus ArrayExpress

    ID: E-GEOD-13887

    Description: r of MHP which in turn enhanced the expression of HRES-1/Rab4, a small GTPase that regulates recycling of surface receptors through early endosomes. Expression of HRES-1/Rab4 was increased in SLE T cells and, in accordance with its dominant impact on the endocytic recycling of CD4, it was inversely correlated with diminished CD4 expression. HRES-1/Rab4 over-expression was also inversely correlated with diminished TCRζ protein levels. Combined with follow up studies, these results suggest that activation of mTOR causes the loss of TCRζ in lupus T cells through HRES-1/Rab4-dependent lysosomal degradation. Experiment Overall Design: 10 replicate T cell samples fro...

  5. GppNHp-Bound Rab4A PDB

    ID: PDB:1YU9

    Description: GTP-binding protein

  6. Activation of mTOR controls the loss of TCR? in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation GEMMA

    ID: 1056

    Keywords: functional genomics

    Description: r of MHP which in turn enhanced the expression of HRES-1/Rab4, a small GTPase that regulates recycling of surface receptors through early endosomes. Expression of HRES-1/Rab4 was increased in SLE T cells and, in accordance with its dominant impact on the endocytic recycling of CD4, it was inversely correlated with diminished CD4 expression. HRES-1/Rab4 over-expression was also inversely correlated with diminished TCR? protein levels. Combined with follow up studies, these results suggest that activation of mTOR causes the loss of TCR? in lupus T cells through HRES-1/Rab4-dependent lysosomal degradation. Last Updated (by provider): Feb 20 2009 Contributers: Sanj...

  7. Transcription profiling by array of human CD3-positive T cells from patients with systemic lupus erythematosus OmicsDI

    ID: E-GEOD-13887

    Date Released: 04-29-2015

    Description: r of MHP which in turn enhanced the expression of HRES-1/Rab4, a small GTPase that regulates recycling of surface receptors through early endosomes. Expression of HRES-1/Rab4 was increased in SLE T cells and, in accordance with its dominant impact on the endocytic recycling of CD4, it was inversely correlated with diminished CD4 expression. HRES-1/Rab4 over-expression was also inversely correlated with diminished TCRζ protein levels. Combined with follow up studies, these results suggest that activation of mTOR causes the loss of TCRζ in lupus T cells through HRES-1/Rab4-dependent lysosomal degradation. Experiment Overall Design: 10 replicate T cell samples fro...

  8. RAB4A_DANRE UniProt:Swiss-Prot

    ID: Q6PHI9

    Description: Ras-related protein Rab-4A GTP GTP GTP GTP Effector region Cysteine methyl ester S-geranylgeranyl cysteine S-geranylgeranyl cystein...

  9. RFIP1_RAT UniProt:Swiss-Prot

    ID: Q3B7T9

    Description: Rab11 family-interacting protein 1 C2 FIP-RBD Necessary for interaction with RAB4A and RAB11A, subc...

  10. RAB4A_BOVIN UniProt:Swiss-Prot

    ID: Q2TBH7

    Description: Ras-related protein Rab-4A GTP GTP GTP GTP Effector region Phosphoserine Phosphoserine; by CDK1 Cysteine methyl ester S-geranylgera...

  11. SC6A4_BOVIN UniProt:Swiss-Prot

    ID: Q9XT49

    Description: t serotonin transporter Cytoplasmic Helical; Name=1 Extracellular Helical; Name=2 Cytoplasmic Helical; Name=3 Extracellular Helical; Name=4 Cytoplasmic Helical; Name=5 Extracellular Helical; Name=...

  12. SC6A4_CAVPO UniProt:Swiss-Prot

    ID: O35899

    Description: t serotonin transporter Cytoplasmic Helical; Name=1 Extracellular Helical; Name=2 Cytoplasmic Helical; Name=3 Extracellular Helical; Name=4 Cytoplasmic Helical; Name=5 Extracellular Helical; Name=...

  13. SC6A4_MACMU UniProt:Swiss-Prot

    ID: Q9MYX0

    Description: t serotonin transporter Cytoplasmic Helical; Name=1 Extracellular Helical; Name=2 Cytoplasmic Helical; Name=3 Extracellular Helical; Name=4 Cytoplasmic Helical; Name=5 Extracellular Helical; Name=...


Displaying 13 of 13 results for "RAB4A"