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Displaying 20 of 541 results for "PTPRA"
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  1. Crystal structure of the D2 domain of RPTPa PDB

    ID: PDB:1P15

    Description: Protein-tyrosine phosphatase alpha (E.C.3.1.3.48)

  2. Protein Tyrosine Phosphatase UBASH3B is Overexpressed in Triple-Negative Breast Cancer and Promotes Invasion and Metastasis BioProject

    ID: PRJNA153615

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Data from: Genome-wide association study identifies novel loci associated with resistance to bovine tuberculosis Dryad

    DateIssued: 04-17-2014

    Description: Tuberculosis caused by Mycobacterium bovis is a re- emerging disease of livestock which is of major economic importance world-wide, as well as being a zoonoti...

  4. PTP1B deficiency effect on mammary gland development and differentiation BioProject

    ID: PRJNA178146

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Analysis of protein tyrosine phosphatase 1B (PTP1B) deficient mammary glands from nulliparous mice at est...
  5. Gene Expression Profile of Motheaten Mice (meb2) with novel mutation in Ptpn6 gene ArrayExpress

    ID: E-GEOD-17161

    Description: unknown etiology. Motheaten mice with mutation in protein tyrosine phosphatase Ptpn6 have massive neutrophilic infiltration within the skin followed by autoinflammatory and autoimmune systemic pathology resembling similarity to neutrophilic dermatoses in human. Keywords: genetic modification We performed microarray study on motheaten mice with novel mutation (meb2) in protein tyrosine phosphatase

  6. Expression data from Shp2f/f and SCSKO mice testis ArrayExpress

    ID: E-GEOD-68829

    Description: ity of Sertoli cells remained largely unexplored. Tyrosine phosphatase protein Shp2 is expressed in germ, Leydig and Sertoli cells of mice testes. But the physiological role of Shp2 in the spermatogenesis was not fully understood. Thus, we conditionally deleted Shp2 gene ...

  7. RNA-seq Analysis of Wild Type and Ptpn11-deficient cerebellar Transcriptomes BioProject

    ID: PRJNA343552

    Access Type: download

  8. PTP1B deficiency effect on mammary gland development and differentiation ArrayExpress

    ID: E-GEOD-41768

    Description: Analysis of protein tyrosine phosphatase 1B (PTP1B) deficient mammary glands from nulliparous mice at est...

  9. Progression from actinic keratosis to cutaneous squamous cell carcinoma involves miR-204 silencing and a switch towards STAT3 activation BioProject

    ID: PRJNA292560

    Keywords: Transcriptome or Gene expression

    Access Type: download

  10. Expression data of hepatic iNKT cells from pLck-hCD1d transgenic mice BioProject

    ID: PRJNA183540

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ck-CD1d tg mice express significantly less SHP-1, a tyrosine phosphatase negatively regulating TCR signaling, than WT cells. iNKT cells from heterozygous SHP-1-mutated motheaten mice, displaying similar SHP-1 reduction as pLck-CD1d tg iNKT cells, are antigen-hyperresponsive. Restoring normal CD1d expression in pLck-CD1d tg mice normalizes SHP-1 expression and responsiveness of iNKT cells. In WT mice, iNKT cells upregulate SHP-1 and decrease responsiveness upon emigration from thymus to periphery. This depends on contacts with CD1d-expressing DCs. iNKT cell fun...
  11. Transcription profiling of sogenic Lrp(+) and Lrp(-) strains in cells growing in steady state in glucose minimal medium, either in the presence or ... ArrayExpress

    ID: E-SMDB-1726

    Description: s evidence that the leucine-responsive regulatory protein (Lrp) may play an important role in stationary phase, so this study used microarrays representing >98% of E. coli genes to more comprehensively identify those controlled by Lrp. The primary analysis compared isogenic Lrp(+) and Lrp(-) strains in cells growing in steady sta...

  12. Crystal structure of a C-terminal phosphatase domain of Rattus norvegicus ortholog of human protein tyrosine phosphatase, receptor type, D (PTPRD) PDB

    ID: PDB:2NV5

    Description: PTPRD, PHOSPHATASE

  13. Gene regulation following MIF stimulation ArrayExpress

    ID: E-GEOD-33352

    Description: uced by cell surface receptors. Here, we describe a novel biological mechanism essential for survival and homeostasis of normal peripheral mature B cells and chronic lymphocytic leukemia (CLL) cells, regulated by the heparin-binding cytokine, midkine ...

  14. Transcription profiling of sogenic Lrp(+) and Lrp(-) strains in cells growing in steady state in glucose minimal medium, either in the presence or ... OmicsDI

    ID: E-SMDB-1726

    Date Released: 03-27-2012

    Description: s evidence that the leucine-responsive regulatory protein (Lrp) may play an important role in stationary phase, so this study used microarrays representing >98% of E. coli genes to more comprehensively identify those controlled by Lrp. The primary analysis compared isogenic Lrp(+) and Lrp(-) strains in cells growing in steady sta...

  15. Gene regulation following MIF stimulation. BioProject

    ID: PRJNA149027

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: uced by cell surface receptors. Here, we describe a novel biological mechanism essential for survival and homeostasis of normal peripheral mature B cells and chronic lymphocytic leukemia (CLL) cells, regulated by the heparin-binding cytokine, midkine ...
  16. CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 4, PDZ DOMAIN PDB

    ID: PDB:2VPH

    Description: TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 4 (E.C.3...

  17. Expression data of hepatic iNKT cells from pLck-hCD1d transgenic mice ArrayExpress

    ID: E-GEOD-42835

    Description: ck-CD1d tg mice express significantly less SHP-1, a tyrosine phosphatase negatively regulating TCR signaling, than WT cells. iNKT cells from heterozygous SHP-1-mutated motheaten mice, displaying similar SHP-1 reduction as pLck-CD1d tg iNKT cells, are antigen-hyperresponsive. Restoring normal CD1d expression in pLck-CD1d tg mice normalizes SHP-1 expression and responsiveness of iNKT cells. In WT mice, iNKT cells upregulate SHP-1 and decrease responsiveness upon emigration from thymus to periphery. This depends on contacts with CD1d-expressing DCs. iNKT cell fun...

  18. Microarray of wild type, Shp2 knock-out, Pten knock-out and double knock-out erythroblasts ArrayExpress

    ID: E-GEOD-48477

    Description: ythroblasts isolated from the bone marrow of wide type, Shp2 knock-out, Pten knock-out and double knock-out mice...

  19. MCF10A-HER2/3 cells grown in 3D cultures in the presence or absence of SHP2 BioProject

    ID: PRJNA156321

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: oncogene was the Src-homology 2 domain-containing phosphatase SHP2 (encoded by PTPN11), an ubiquitously expressed PTP that transduces mitogenic, pro-survival, cell fate and/or pro-migratory signals from numerous...
  20. Genome wide expression analysis of FACS-isolated Shp2 mutant neonatal myogenic progenitor cells BioProject

    ID: PRJNA381774

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ure appropriate muscle growth and repair. The non-receptor tyrosine phosphatase Shp2 (Ptpn11) is an important transducer of growth factor and cytokine signaling. Here we combined complex genetic analyses, biochemical studies and pharmacological interference to ...

Displaying 20 of 541 results for "PTPRA"