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Displaying 20 of 143 results for "PTPN1"
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  1. RNA-seq analysis of IL-10 treatment of wildtype and Ptpn1-/- knockout peritoneal macrophages BioProject

    ID: PRJNA213962

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Expression changes induced by PTPN1 knockdown in KM-H2 cells BioProject

    ID: PRJNA235318

    Keywords: Transcriptome or Gene expression

    Access Type: download

  3. Expression changes induced by PTPN1 knockdown in KM-H2 cells ArrayExpress

    ID: E-GEOD-54157

    Description: Gene expression data for shRNA PTPN1 knockdown vs. Non-silencing in the classical Hodgkin lymphoma-derived cell line KM-H2 A total of 4 samples were analyzed (2 K...

  4. RNA-seq analysis of IL-10 treatment of wildtype and Ptpn1-/- knockout peritoneal macrophages ArrayExpress

    ID: E-GEOD-49449

    Description: ate cells (macrophages) purified from wildtype or Ptpn1 (PTP1B) knockout mice, either treated or untreated with IL-10. In periotenal macrophages IL-10 activates the transcription factor STAT3 to execute and anti-inflammatory gene expression program...

  5. Recurrent Somatic Mutations of PTPN1 in Primary Mediastinal B cell lymphoma and Hodgkin Lymphoma OmicsDI

    ID: EGAS00001000554

    Date Released:

    Description: quence mutations of the tyrosine phosphatase gene PTPN1 in the tumor genomes and transcriptomes of these B cell lymphomas (6 of 30 or in 20% of HL cases and 13 of 49 or in 27% of PMBCL cases), consisting of nonsense, missense and frameshift mutations. We demonstrate that PTPN1 mutations lead to reduced phosphatase activity and increased phosphorylation of JAK-S...

  6. RNA-seq analysis of IL-10 treatment of wildtype and Ptpn1-/- knockout peritoneal macrophages OmicsDI

    ID: E-GEOD-49449

    Date Released: 06-19-2014

    Description: ate cells (macrophages) purified from wildtype or Ptpn1 (PTP1B) knockout mice, either treated or untreated with IL-10. In periotenal macrophages IL-10 activates the transcription factor STAT3 to execute and anti-inflammatory gene expression program...

  7. Expression changes induced by PTPN1 knockdown in KM-H2 cells OmicsDI

    ID: E-GEOD-54157

    Date Released: 05-13-2014

    Description: Gene expression data for shRNA PTPN1 knockdown vs. Non-silencing in the classical Hodgkin lymphoma-derived cell line KM-H2 A total of 4 samples were analyzed (2 K...

  8. High-resolution genomic profiling of marginal zone B-cell lymphomas and variants ArrayExpress

    ID: E-GEOD-36311

    Description: fy gains of prominent (proto)oncogenes REL, ETS1, PTPN1, PTEN and KRAS that were associated exclusively with the large cell presentation of MALT lymphoma. Losses of ADAM3A and SCAPER, as well as gains of SIRPB1 occur during progression from small cell to large cell lymphoma. In two case studies, we examined lymphoma progression comparing two different regions of the same tumor and material acquired at two different time points from another lymphoma. Our analyses r...

  9. PRJEB14456 BioProject

    Keywords: Other

    Access Type: download

    dataset.description: alterations of these and other genes (JAK1, JAK2, PTPN1) in 89% of patients, documenting its pivotal role in cHL pathogenesis....
  10. PTP1B deficiency effect on mammary gland development and differentiation ArrayExpress

    ID: E-GEOD-41768

    Description: Analysis of protein tyrosine phosphatase 1B (PTP1B) deficient mammary glands from nulliparous mice at estrous and pregnancy day 3, 7, 10 and 15. We us...

  11. PTP1B deficiency effect on mammary gland development and differentiation BioProject

    ID: PRJNA178146

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Crystal structure of PTP1B with Bicyclic Thiophene inhibitor PDB

    ID: PDB:2AZR

    Description: Tyrosine-protein phosphatase, non-receptor type 1 (E.C.3.1.3.48)

    gene.name: PTPN1, PTP1B
  13. Crystal structure of a complex between PTP1B and the insulin receptor tyrosine kinase PDB

    ID: PDB:2B4S

    Description: Tyrosine-protein phosphatase, non-receptor type 1 (E.C.3.1.3.48), Insulin receptor (E.C.2.7.1.112)

    gene.name: PTPN1, PTP1B
  14. The second sphere residue T263 is important for function and activity of PTP1B through modulating WPD loop PDB

    ID: PDB:4QBW

    Description: Tyrosine-protein phosphatase non-receptor type 1 (E.C.3.1.3.48)

    gene.name: PTPN1, PTP1B
  15. CRYSTAL STRUCTURE OF APO HUMAN PTP1B (C215S) MUTANT PDB

    ID: PDB:1I57

    Description: PHOSPHO-TYROSINE PHOSPHATASE 1B (E.C.3.1.3.48)

  16. Ptp1B R47C Modified at C47 with N-[4-(2-{2-[3-(2-Bromo-acetylamino)-propionylamino]-3-hydroxy-propionylamino}-ethyl)-phenyl]-oxalamic acid PDB

    ID: PDB:1NWE

    Description: Protein-tyrosine phosphatase, non-receptor type 1 (E.C.3.1.3.48)

    gene.name: PTPN1
  17. Crystal structure of PTP1B with monocyclic thiophene inhibitor PDB

    ID: PDB:2H4G

    Description: Tyrosine-protein phosphatase non-receptor type 1 (E.C.3.1.3.48)

    gene.name: PTPN1, PTP1B
  18. Crystal structure of the PTP1B complexed with SP7343-SP7964, a pTyr mimetic PDB

    ID: PDB:1NWL

    Description: protein-tyrosine phosphatase, non-receptor type 1 (E.C.3.1.3.48)

    gene.name: PTPN1
  19. Oxalyl-aryl-Amino Benzoic acid Inhibitors of PTP1B, compound 8b PDB

    ID: PDB:1ONZ

    Description: Protein-tyrosine phosphatase, non-receptor type 1 (E.C.3.1.3.48)

    gene.name: PTPN1 OR PTP1B
  20. Structure of PTP1B inactivated by H2O2/bicarbonate PDB

    ID: PDB:3SME

    Description: Tyrosine-protein phosphatase non-receptor type 1 (E.C.3.1.3.48)

    gene.name: PTP1B, PTPN1

Displaying 20 of 143 results for "PTPN1"