PTP4A3 | bioCADDIE Data Discovery Index
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Displaying 20 of 44 results for "PTP4A3"
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  1. PRL-R alignment Dryad

    DateIssued: 03-25-2013

    Description: PRL-R alignment

  2. Solution Structure of human PRL-3 PDB

    ID: PDB:1R6H

    Description: protein tyrosine phosphatase type IVA,

  3. Solution Structure of human holo-PRL-3 in complex with vanadate PDB

    ID: PDB:2MBC

    Description: Protein tyrosine phosphatase type IVA 3

  4. Receptor-independent ectopic activity of PROLACTIN predicts aggressive lung tumors and indicates HDACi-based therapeutic strategies ArrayExpress

    ID: E-GEOD-49544

    Description: Aim: PROLACTIN (PRL), normally produced by the pituitary gland, acts through its receptor (PRL-R) to initiate...

  5. Crystal structure of PRL-3 phosphatase in complex with the Bateman domain of CNNM3 magnesium transporter PDB

    ID: PDB:5TSR

    Description: Protein tyrosine phosphatase type IVA 3

  6. Receptor-independent ectopic activity of PROLACTIN predicts aggressive lung tumors and indicates HDACi-based therapeutic strategies. BioProject

    ID: PRJNA214224

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: Aim: PROLACTIN (PRL), normally produced by the pituitary gland, acts through its receptor (PRL-R) to initiate...
  7. Investigation of the role of PRL-3 in leukemogenesis BioProject

    ID: PRJNA272424

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Receptor-independent ectopic activity of PROLACTIN predicts aggressive lung tumors and indicates HDACi-based therapeutic strategies. OmicsDI

    ID: E-GEOD-49544

    Date Released: 08-08-2014

    Description: Aim: PROLACTIN (PRL), normally produced by the pituitary gland, acts through its receptor (PRL-R) to initiate...

  9. Retroviral Integration Mutagenesis in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression as a Prognostic Indicator BioProject

    ID: PRJNA121891

    Keywords: Epigenomics

    Access Type: download

  10. Retroviral Integration Mutagenesis in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression as a Prognostic Indicator ArrayExpress

    ID: E-GEOD-19706

    Description: cls1 and Prkrir, were up regulated and one, i.e., Ptp4a3, was down regulated in the affected tumor. Next, we investigated the role of PTP4A3 in human AML and we show that PTP4A3 expression is a negative prognostic indicator, independent of other prognostic parameters. In conclusion, our novel strategy has identified PTP4A3 to potentially have a role in AML, on one hand as a candidate HIG contributing to leukemogenesis in mice and on the other hand as a prognostic indicator in human AML. We designed a new strategy to specifically identify DNA methylated proviral integrations on a large scale by combining methylated DNA immunoprecipitation (MeDIP), inverse PCR and promoter array hybridization. We used 6 murine leukemia samples from a previous screen that were induced by injecting Gr 1.4 MLV into newborn mice....

  11. Retroviral Integration Mutagenesis in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression as a Prognostic Indicator OmicsDI

    ID: E-GEOD-19706

    Date Released: 11-14-2011

    Description: cls1 and Prkrir, were up regulated and one, i.e., Ptp4a3, was down regulated in the affected tumor. Next, we investigated the role of PTP4A3 in human AML and we show that PTP4A3 expression is a negative prognostic indicator, independent of other prognostic parameters. In conclusion, our novel strategy has identified PTP4A3 to potentially have a role in AML, on one hand as a candidate HIG contributing to leukemogenesis in mice and on the other hand as a prognostic indicator in human AML. We designed a new strategy to specifically identify DNA methylated proviral integrations on a large scale by combining methylated DNA immunoprecipitation (MeDIP), inverse PCR and promoter array hybridization. We used 6 murine leukemia samples from a previous screen that were induced by injecting Gr 1.4 MLV into newborn mice....

  12. Structure of human PRL-3, the phosphatase associated with cancer metastasis PDB

    ID: PDB:1V3A

    Description: protein tyrosine phosphatase type IVA(E.C.3.1.3.48)

  13. TP4A3_BOVIN UniProt:Swiss-Prot

    ID: A2VDT1

    Description: Protein tyrosine phosphatase type IVA 3

  14. Expression profile of HEK293 cells stably transfected with PRL-1 (PTP4A1) or empty pcDNA4 vector (control) ArrayExpress

    ID: E-GEOD-42586

    Description: The multifunctional protein tyrosine phosphatase PRL-1 (Gene Symbol: PTP4A1) has been identif...

  15. Expression profile of HEK293 cells stably transfected with PRL-1 (PTP4A1) or empty pcDNA4 vector (control) BioProject

    ID: PRJNA182320

    Keywords: Transcriptome or Gene expression

    Access Type: download

  16. Expression profile of HEK293 cells stably transfected with PRL-1 (PTP4A1) or empty pcDNA4 vector (control) OmicsDI

    ID: E-GEOD-42586

    Date Released: 05-13-2014

    Description: The multifunctional protein tyrosine phosphatase PRL-1 (Gene Symbol: PTP4A1) has been identif...

  17. Overexpression of prl3 in zebrafish embryos OmicsDI

    ID: E-ERAD-455

    Date Released: 07-11-2016

    Description: Over expression of prl3 by use of outcrossed tg(actin:prl3) fish comparing prl3 overexpression to wild type sibl...

  18. Copy number variation analysis of hepatic metastases from uveal melanoma ArrayExpress

    ID: E-GEOD-69614

    Description: on 8q24.3. Interestingly, deletions on chromosome 3 were detected at a lower frequency. Genomic profiles of PUM-MUM pairs varied in their degree of similarity and complexity. No genes were altered being unique to either all PUMs or all MUMs of the pairs, but 135 gene CNVs were consistently shared. Of these genes, 125 were amplifications located on chr. 8q24.3. Five genes in the region 8q24.3 and two genes on chromosome 3 were selected for validation by immunohistochemistry because of their known function in cancer (BCL6, C-MYC, E2F5, PTP4A3, SNAI2, and WISP1), or known importance in UM pathology (BAP1). The functional effect of these CNVs on protein expression was confirmed; amplified genes showed increased expression and deleted genes reduced expression. To conclude, our data demonstrate frequent amplification of chromosome 8q in ...

  19. Overexpression of prl3 in zebrafish embryos ArrayExpress

    ID: E-ERAD-455

    Description: Over expression of prl3 by use of outcrossed tg(actin:prl3) fish comparing prl3 overexpression to wild type sibl...

  20. Crystal Structure of PRL-1 complex with compound analogy 3 PDB

    ID: PDB:5BX1

    Description: Protein tyrosine phosphatase type IVA 1 (E.C.3.1.3.48)


Displaying 20 of 44 results for "PTP4A3"