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Displaying 20 of 20 results for "PSRC1"
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  1. Plasma autoantibody associated with basal-like breast cancer-GST3 Array ArrayExpress

    ID: E-GEOD-68116

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  2. Plasma autoantibody associated with basal-like breast cancer-GST2 Array ArrayExpress

    ID: E-GEOD-68115

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  3. PSRC1_BOVIN UniProt:Swiss-Prot

    ID: Q29RJ9

    Description: Proline/serine-rich coiled-coil protein 1 1 2 3 4 5 6 6 X 4 AA repeats of P-X-X-P Pro/Ser-rich Phosphoserine Phosphoserine Phosphoserine Phosphoserine...

    gene.name: PSRC1
  4. Plasma autoantibody associated with basal-like breast cancer-GST4 Array ArrayExpress

    ID: E-GEOD-68117

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  5. Plasma autoantibody associated with basal-like breast cancer-FLAG Array ArrayExpress

    ID: E-GEOD-68118

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  6. Plasma autoantibody associated with basal-like breast cancer-GST1 Array ArrayExpress

    ID: E-GEOD-68114

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  7. Plasma autoantibody associated with basal-like breast cancer-GST4 Array BioProject

    ID: PRJNA282095

    Keywords: Proteome

    Access Type: download

    dataset.description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. Overall design: The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...
  8. Plasma autoantibody associated with basal-like breast cancer-GST3 Array BioProject

    ID: PRJNA282096

    Keywords: Proteome

    Access Type: download

    dataset.description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. Overall design: The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...
  9. Plasma autoantibody associated with basal-like breast cancer-FLAG Array BioProject

    ID: PRJNA282094

    Keywords: Proteome

    Access Type: download

    dataset.description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. Overall design: The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...
  10. Induced Pluripotent Stem Cell Differentiation Provides an Approach for Functional Validation of GWAS Variants in Metabolic Disease BioProject

    ID: PRJNA355845

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: es, in particular expression of SORT1, CELSR2 and PSRC1, consistent with previous analysis of this variant using other approaches. Initial investigation of additional SNPs also highlighted correlations with gene expression. Thus, iPSC-based population studies seem promising for further development as a tool for the functional validation of GWAS variants. Overall design: 68 Induced Pluripotent Stem Cell Lines derived from 34 Participants Differentiated into white adipocytes and hepatocyte like cells...
  11. A protein network of common susceptibility genes provides a link in the genetic architecture of chronic inflammation and cardiovascular disease ArrayExpress

    ID: E-GEOD-54989

    Description: ase phenotype. Interestingly, CDKN2B, and CELSR2/PSRC1/MYBPHL/SORT1, unequivocally replicated CVD loci, are integrated within this network as are several SNPs located in transcription factor recognition sequences, i.e. NFKB1, STAT3, which are key factors in inflammation. Finally, we observed a significant enrichment of inflammatory variants within CVD cluster loci that are targets of selection. Overall, 32 genes exhibit traces of selection, 16 of which are part of the PPI, further suggesting that recent selective sweeps may have affected the genomic architecture underlying CVD. 6 samples, no replicates....

  12. Plasma autoantibody associated with basal-like breast cancer-GST1 Array BioProject

    ID: PRJNA282085

    Keywords: Proteome

    Access Type: download

    dataset.description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. Overall design: The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...
  13. Plasma autoantibody associated with basal-like breast cancer-GST2 Array BioProject

    ID: PRJNA282097

    Keywords: Proteome

    Access Type: download

    dataset.description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. Overall design: The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...
  14. Plasma autoantibody associated with basal-like breast cancer-GST2 Array OmicsDI

    ID: E-GEOD-68115

    Date Released: 04-27-2015

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  15. Plasma autoantibody associated with basal-like breast cancer-GST3 Array OmicsDI

    ID: E-GEOD-68116

    Date Released: 04-27-2015

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  16. Plasma autoantibody associated with basal-like breast cancer-GST4 Array OmicsDI

    ID: E-GEOD-68117

    Date Released: 04-27-2015

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  17. Plasma autoantibody associated with basal-like breast cancer-FLAG Array OmicsDI

    ID: E-GEOD-68118

    Date Released: 04-27-2015

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  18. Plasma autoantibody associated with basal-like breast cancer-GST1 Array OmicsDI

    ID: E-GEOD-68114

    Date Released: 04-27-2015

    Description: 6, PPHLN1, PIP4K2C, ZBTB16, TAS2R8, WBP2NL, DOK2, PSRC1, MN1, TRIM21) that distinguished BLBC from controls with 33% sensitivity and 98% specificity. We also discovered a strong association of TP53 AAb with its protein expression (p=0.009) in BLBC patients. Conclusions: These AAbs warrant further investigation in clinical studies to determine their value for further understanding the biology of BLBC and possible detection. The immunoreactivity was compared between 45 BLBC cases and 45 controls against 10,000 human proteins that printed on microscopic slides...

  19. A protein network of common susceptibility genes provides a link in the genetic architecture of chronic inflammation and cardiovascular disease BioProject

    ID: PRJNA238216

    Keywords: Transcriptome or Gene expression

    Access Type: download

    dataset.description: ase phenotype. Interestingly, CDKN2B, and CELSR2/PSRC1/MYBPHL/SORT1, unequivocally replicated CVD loci, are integrated within this network as are several SNPs located in transcription factor recognition sequences, i.e. NFKB1, STAT3, which are key factors in inflammation. Finally, we observed a significant enrichment of inflammatory variants within CVD cluster loci that are targets of selection. Overall, 32 genes exhibit traces of selection, 16 of which are part of the PPI, further suggesting that recent selective sweeps may have affected the genomic architecture underlying CVD. Overall design: 6 samples, no replicates....
  20. A protein network of common susceptibility genes provides a link in the genetic architecture of chronic inflammation and cardiovascular disease OmicsDI

    ID: E-GEOD-54989

    Date Released: 09-05-2015

    Description: ase phenotype. Interestingly, CDKN2B, and CELSR2/PSRC1/MYBPHL/SORT1, unequivocally replicated CVD loci, are integrated within this network as are several SNPs located in transcription factor recognition sequences, i.e. NFKB1, STAT3, which are key factors in inflammation. Finally, we observed a significant enrichment of inflammatory variants within CVD cluster loci that are targets of selection. Overall, 32 genes exhibit traces of selection, 16 of which are part of the PPI, further suggesting that recent selective sweeps may have affected the genomic architecture underlying CVD. 6 samples, no replicates....


Displaying 20 of 20 results for "PSRC1"