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Displaying 20 of 47 results for "PRKCH"
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  1. PKC eta kinase in complex with a naphthyridine PDB

    ID: PDB:3TXO

    Description: Protein kinase C eta type (E.C.2.7.11.13)

  2. Human protein kinase C, eta PDB

    ID: PDB:2FK9

    Description: protein kinase C, eta type (E.C.2.7.1.37)

  3. Expression data from Prkch-/-Apoe-/- mouse BioProject

    ID: PRJNA164669

    Keywords: Transcriptome or Gene expression

    Access Type: download

  4. OCLN_CANLF UniProt:Swiss-Prot

    ID: Q28269

    Description: sphotyrosine Phosphotyrosine Phosphothreonine; by PKC/PRKCH Phosphothreonine; by PKC/PRKCH Phosphoserine Phosphoserine...

  5. OCLN_PONAB UniProt:Swiss-Prot

    ID: Q5RFS5

    Description: sphotyrosine Phosphotyrosine Phosphothreonine; by PKC/PRKCH Phosphothreonine; by PKC/PRKCH Phosphoserine Phosphoserine...

  6. OCLN_POTTR UniProt:Swiss-Prot

    ID: Q28793

    Description: sphotyrosine Phosphotyrosine Phosphothreonine; by PKC/PRKCH Phosphothreonine; by PKC/PRKCH Phosphoserine Phosphoserine...

  7. Epigenetic signatures of gestational diabetes mellitus on ATP5A1, PRKCH, SLC17A4 and HIF3A cord blood methylation BioProject

    ID: PRJNA349175

    Keywords: Epigenomics

    Access Type: download

  8. KPCL_RAT UniProt:Swiss-Prot

    ID: Q64617

    Description: Protein kinase C eta type C2 Protein kinase

  9. Genome-wide profiling of Argonaute-chromosome interactions [ChIP-Seq] BioProject

    ID: PRJNA174235

    Keywords: Epigenomics

    Access Type: download

    dataset.description: etailed analysis of these genes including PIK3CA, PRKCH, CDC6 and RRM1 verified Ago1-mediated transcriptional gene regulation through Ago1-promoter interactions. We also found a strong correlation between Ago1-bound genes and genes downregulated by Ago1 depletion which, phenotypically, leads to inhibition of proliferation in different cancer cells. Therefore, our findings reveal the first landscape of human Ago1-chromosomal interactions which may drive oncogenic programs in cancer cells Overall design: Examination of Ago-DNA interactions in human cancer cells...
  10. Genome-wide profiling of Argonaute-chromosome interactions [ChIP-Seq] ArrayExpress

    ID: E-GEOD-40536

    Description: etailed analysis of these genes including PIK3CA, PRKCH, CDC6 and RRM1 verified Ago1-mediated transcriptional gene regulation through Ago1-promoter interactions. We also found a strong correlation between Ago1-bound genes and genes downregulated by Ago1 depletion which, phenotypically, leads to inhibition of proliferation in different cancer cells. Therefore, our findings reveal the first landscape of human Ago1-chromosomal interactions which may drive oncogenic programs in cancer cells Examination of Ago-DNA interactions in human cancer cells...

  11. Crystal Structure of PKC-theta complexed with Staurosporine at 2A resolution PDB

    ID: PDB:1XJD

    Description: Crystal Structure of PKC-theta complexed with Staurosporine at 2A resolution

  12. Genome-wide profiling of Argonaute-chromosome interactions [ChIP-Seq] OmicsDI

    ID: E-GEOD-40536

    Date Released: 10-07-2013

    Description: etailed analysis of these genes including PIK3CA, PRKCH, CDC6 and RRM1 verified Ago1-mediated transcriptional gene regulation through Ago1-promoter interactions. We also found a strong correlation between Ago1-bound genes and genes downregulated by Ago1 depletion which, phenotypically, leads to inhibition of proliferation in different cancer cells. Therefore, our findings reveal the first landscape of human Ago1-chromosomal interactions which may drive oncogenic programs in cancer cells Examination of Ago-DNA interactions in human cancer cells...

  13. CDK-2 with indazole inhibitor 9 bound at its active site PDB

    ID: PDB:3EZV

    Description: CDK-2 with indazole inhibitor 9 bound at its active site

    dataset.creators: Xing, L.
  14. four human breast cancer cell lines treated with protein kinase C (PKC)-activator Phorbol 12-myristate 13-acetate (PMA) to study the signalling pathway leadin... OmicsDI

    ID: E-MTAB-3487

    Date Released: 04-10-2015

    Description: binding proteins. Among these, the actin-bundling protein L-plastin, initially detected in leukocytes, is ectopically expressed in several solid tumours and is often considered as a metastatic marker. Phosphorylation of L-plastin on residue serine 5 (Ser5) has been shown to activate L-plastin and to be crucial for invasion and met...

  15. Crystal Structure of Wild Type BRAF kinase domain in complex with organometallic inhibitor CNS292 PDB

    ID: PDB:3Q4C

    Description: Serine/threonine-protein kinase B-raf (E.C.2.7.11.1)

  16. CDK-2 with indazole inhibitor 17 bound at its active site PDB

    ID: PDB:3EZR

    Description: CDK-2 with indazole inhibitor 17 bound at its active site

    dataset.creators: Xing, L.
  17. CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site PDB

    ID: PDB:3F5X

    Description: Cell division protein kinase 2 (E.C.2.7.11.22), Cyclin-A2

  18. four human breast cancer cell lines treated with protein kinase C (PKC)-activator Phorbol 12-myristate 13-acetate (PMA) to study the signalling pathway leadin... ArrayExpress

    ID: E-MTAB-3487

    Description: binding proteins. Among these, the actin-bundling protein L-plastin, initially detected in leukocytes, is ectopically expressed in several solid tumours and is often considered as a metastatic marker. Phosphorylation of L-plastin on residue serine 5 (Ser5) has been shown to activate L-plastin and to be crucial for invasion and met...

  19. 84 colonic adenocarcinoma cells co-incubated with L. fermentum or L. gasseri to study the beneficial effects of probiotic bacteria in enhancing epithelial barrier integrity... ArrayExpress

    ID: E-MEXP-3445

    Description: he effects of four probiotic lactobacilli, namely L. acidophilus, L. fermentum, L. gasseri, and L. rhamnosus in a T84 cell epithelial barrier model. Results of DNA-microarray experiments indicating that lactobacilli modulate the regulation of genes encoding in particular adherence junction proteins such as E-cadherin and b-catenin were confirmed by qRT-PCR. Furthermore, we show that epithelial barrier function is modulated by Gram-positive probiotic lactobacilli via their effect on adherence junction protein expression and complex formation. In addition, incubation with lactobacilli differentially influences the phosphorylation of adherence junction proteins and of PKC isoforms such as PK...

  20. Transcription profiling of human cell lines MCF7, COLO-205 and SK-MEL-5 following treatment with PEP008 ArrayExpress

    ID: E-GEOD-8742

    Description: ensitive cells at 100-1000 ng/ml. Use of the pan-PKC inhibitor bisindolylmaleimide-l demonstrated that activation of PKC was required for growth arrest. Full genome expression profiling revealed that pivotal genes involved in DNA synthesis and cell cycle control were down-regulated by treatment in all three sensitive solid tumor models. At the protein level, prolonged down-regulation of E2F-1 and proliferating cell nuclear antigen (PCNA), sustained expression of p21WAF1/CIP1 and dephosphorylation of retinoblastoma (Rb) occurred in the sensitive cells. Although activation of extracellular signal-related kinase (ERK) 1/...


Displaying 20 of 47 results for "PRKCH"