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Displaying 20 of 31 results for "PPM1D"
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  1. Expression data from Wild type and Wip1 knockout Hematopoietic stem cell BioProject

    ID: PRJNA253355

    Keywords: Transcriptome or Gene expression

    Access Type: download

  2. Expression data from Wild type and Wip1 knockout Hematopoietic stem cell ArrayExpress

    ID: E-GEOD-58754

    Description: ulation of DNA damage is a hallmark of HSC aging. Wild-type p53-induced phosphatase 1 (Wip1) is a homeostatic regulator of DNA damage response. We used microarr...

  3. Expression data from Wild type and Wip1 knockout Hematopoietic stem cell OmicsDI

    ID: E-GEOD-58754

    Date Released: 06-27-2014

    Description: ulation of DNA damage is a hallmark of HSC aging. Wild-type p53-induced phosphatase 1 (Wip1) is a homeostatic regulator of DNA damage response. We used microarr...

  4. Murine liver tissues: WT and Wip1 KO mice after Partial Hepatectomy at 24h and 36 h. BioProject

    ID: PRJNA254162

    Keywords: Transcriptome or Gene expression

    Access Type: download

  5. Homo sapiens : Homo sapiens Exome BioProject

    ID: PRJNA322354

    Keywords: exome

    Access Type: download

    dataset.description: d to the discovery of tumor-specific mutations in PPM1D, encoding wild-type p53-induced protein phosphatase 1D (WIP1), in 37.5% of the BSGs that harbored hallmark H3F3A mutations encoding p.Lys27Met substitutions. PPM1D mutations were mutually exclusive with TP53 mutations in BSG and at...
  6. Gene expression in Wip1+/+ or -/- MEFs after gamma radiation BioProject

    ID: PRJNA101937

    Keywords: Transcriptome or Gene expression

    Access Type: download

  7. Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity BioProject

    ID: PRJNA319792

    Keywords: Transcriptome or Gene expression

    Access Type: download

  8. Transcription profiling of mouse embryonic fibroblasys from Wip1+/+ or -/- animals after gamma radiation ArrayExpress

    ID: E-GEOD-8704

    Description: Assessment of p53 targets by gene expression array analysis in irradiated and nonirradiated Wip1+/+ and Wip1

  9. Murine liver tissues: WT and Wip1 KO mice after Partial Hepatectomy at 24h and 36 h ArrayExpress

    ID: E-GEOD-59023

    Description: tional profiling of mouse liver tissues comparing Wild type liver tissues with Wip1 KO mice liver tissues after Partial Hepatectomy at 24h and 36 h. WT ...

  10. Wip1 regulates adult neurogenesis and Wnt signaling during aging BioProject

    ID: PRJNA245440

    Keywords: Transcriptome or Gene expression

    Access Type: download

  11. WIP1 controls global heterochromatin silencing via ATM/BRCA1-dependent DNA methylation BioProject

    ID: PRJNA197260

    Keywords: Transcriptome or Gene expression

    Access Type: download

  12. Wip1 regulates adult neurogenesis and Wnt signaling during aging ArrayExpress

    ID: E-GEOD-57105

    Description: nt mechanism that contributes to this decline via Wip1-dependent regulation of neuronal differentiation. We found that Wip1 is expressed in neural stem/progenitor cells (NPCs) of the mouse subventricular zone and its upregulation at phy...

  13. WIP1 controls global heterochromatin silencing via ATM/BRCA1-dependent DNA methylation ArrayExpress

    ID: E-GEOD-46103

    Description: WIP1 phosphatase is emerging as an important regulator of tumorigenesis, but no unifying mechanistic network has...

  14. Wip1 regulates adult neurogenesis and Wnt signaling during aging OmicsDI

    ID: E-GEOD-57105

    Date Released: 06-03-2014

    Description: nt mechanism that contributes to this decline via Wip1-dependent regulation of neuronal differentiation. We found that Wip1 is expressed in neural stem/progenitor cells (NPCs) of the mouse subventricular zone and its upregulation at phy...

  15. WIP1 controls global heterochromatin silencing via ATM/BRCA1-dependent DNA methylation OmicsDI

    ID: E-GEOD-46103

    Date Released: 06-03-2014

    Description: WIP1 phosphatase is emerging as an important regulator of tumorigenesis, but no unifying mechanistic network has...

  16. Murine liver tissues: WT and Wip1 KO mice after Partial Hepatectomy at 24h and 36 h. OmicsDI

    ID: E-GEOD-59023

    Date Released: 07-15-2014

    Description: tional profiling of mouse liver tissues comparing Wild type liver tissues with Wip1 KO mice liver tissues after Partial Hepatectomy at 24h and 36 h. WT ...

  17. Effect of ARF on the transcription of p53 target genes in homologous recombination deficient cells ArrayExpress

    ID: E-GEOD-51354

    Description: r activated by oncogenic stress, which stabilizes p53. Although p53 is a key component of the response to DNA damage, a similar function for ARF has not been ascribed. In this work we sho...

  18. IBBWP_MAIZE UniProt:Swiss-Prot

    ID: P31862

    Description: Bowman-Birk type wound-induced proteinase inhibitor WIP1 Reactive bond (in Ref. 2; no nucleotide entry)...

  19. Identification of novel biomarkers associated with poor patient outcome in invasive breast carcinoma ArrayExpress

    ID: E-GEOD-73383

    Description: good and poor prognosis. Up-regulation of B3GNT7, PPM1D, TNKS2, PHB and GTSE1 in patients with poor prognosis was confirmed by quantitative RT-PCR in an independent sample set from patients with BC (47 with good prognosis and 8 that presented metastasis). Expression of BAD protein was investigated by immunohistochemistry in 1276 BC samples and confirmed the reduced expression levels in metastatic cases observed in the oligoarray data. These findings point to novel prognostic markers that can distinguish breast carcinoma samples according to clinical course and progression of the disease. Global expression profiles from 38 ductal breast tumor patient samples were used to search for molecular signatures correlated with current prognostic markers. A subset of 24 cases comprising 15 patients that remained free of disease after surgery and 9 patients that developed metastasis was used to identify candidate biomarkers associated with metastatic progression. Candidates were subsequently validated in additional independent samples by RT-qPCR or immunohistochemistry....

  20. Transcription profiling of mouse embryonic fibroblasys from Wip1+/+ or -/- animals after gamma radiation OmicsDI

    ID: E-GEOD-8704

    Date Released: 06-10-2011

    Description: Assessment of p53 targets by gene expression array analysis in irradiated and nonirradiated Wip1+/+ and Wip1


Displaying 20 of 31 results for "PPM1D"